A5055754857- Veterinary Equine Medical Research
- Sports Performance and Training
- Mechanics and Biomechanics Studies
- Burn Injury Management and Outcomes
- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cerebral Palsy and Movement Disorders
- Botulinum Toxin and Related Neurological Disorders
- Wound Healing and Treatments
- Venous Thromboembolism Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- PARP inhibition in cancer therapy
- Sports injuries and prevention
- Infection Control in Healthcare
- Veterinary Pharmacology and Anesthesia
- Ergonomics and Musculoskeletal Disorders
- Lipoproteins and Cardiovascular Health
- Medical Device Sterilization and Disinfection
- Safety Warnings and Signage
- Gastrointestinal motility and disorders
- Atrial Fibrillation Management and Outcomes
- Tendon Structure and Treatment
- Congenital gastrointestinal and neural anomalies
- Intracerebral and Subarachnoid Hemorrhage Research
Ulverscroft (United Kingdom)
2015-2025
Johns Hopkins University
2024-2025
Johns Hopkins Bayview Medical Center
2024
Johns Hopkins Medicine
2024
Duke Raleigh Hospital
2024
Tulane University
2024
Florida Atlantic University
2024
Children's Mercy Hospital
2018-2023
University of Missouri–Kansas City
2023
University of Iowa
2006-2023
BACKGROUND: Conducting an adequately powered survival study in idiopathic pulmonary fibrosis (IPF) is challenging due to the rare nature of disease and need for extended follow-up. Consequently, registration trials IPF treatments have not been designed estimate long-term survival. OBJECTIVE: To predict life expectancy patients with receiving pirfenidone versus best supportive care (BSC) a population that met inclusion criteria enrolled ASCEND CAPACITY trials. METHODS: Kaplan-Meier data BSC...
Gout and rheumatoid arthritis are the 2 most common inflammatory arthritides.As hospitalizations for these conditions incur substantial resource use, hospitalization trends associated costs provide key benchmarks of disease burden.However, relevant long-term data scarce.We evaluated US gout from 1993-2011.We investigated arthritides simultaneously, as we hypothesized opposing (due to improvement in care a worsening epidemiology 1 suboptimal ) each condition would serve an internal comparison other.
<h3>Importance</h3> Surgical site infections increase patient morbidity and health care costs. The Centers for Disease Control Prevention emphasize improved basic preventive measures to reduce bacterial transmission among patients undergoing surgery. <h3>Objective</h3> To assess whether can perioperative<i>Staphylococcus aureus</i>transmission surgical infections. <h3>Design, Setting, Participants</h3> This randomized clinical trial was conducted from September 20, 2018, 2019, 19 surgeons...
Supermicrosurgical lymphaticovenular anastomosis (LVA) is a promising treatment modality for lymphedema. However, its practice restricted by the surgeon/equipment-related factors, and effectiveness limited technical constraints. We conducted pilot study to evaluate feasibility of modified "octopus" LVA technique in addressing above problems.Nine consecutive lymphedema patients underwent procedure using technique. Six had upper extremity disease; three lower disease. Except one patient having...
Summary A saddle that does not fit either a horse or rider correctly has potentially far reaching consequences for both and health. The should be assessed off on the horse, without with rider. of must evaluated. well‐fitted distribute weight evenly via panels to horse's thoracic region, complete clearance spinous processes by gullet. remain fairly still during ridden exercise at all paces. also enable them sit in balance. Signs an ill‐fitting include equine thoracolumbar pain, focal...
The aim was to evaluate the cost-effectiveness of niraparib compared with routine surveillance (RS), olaparib and rucaparib for maintenance treatment patients recurrent ovarian cancer (OC). A decision-analytic model estimated cost per quality-adjusted life-year (QALY) gained versus RS, olaparib, from a US payer perspective. considered OC or without germline BRCA mutations (gBRCAmut non-gBRCAmut), who were responsive their last platinum-based chemotherapy regimen. Model health states were:...
Abstract Background Poor noseband adjustment could create high pressures that may risk pain or tissue damage. Objectives To quantify sub‐noseband dorsally over the nasal bone and ventrally mandibular rami for a Cavesson, Swedish (crank), Drop Flash at five tightness levels (2.0 to 0.0 finger equivalents). Study design In vivo experiments. Methods Eight high‐level dressage horses were ridden trot in straight line by their usual riders. Two small pressure mats, attached rami, collected force...
Introduction: Chronic kidney disease (CKD) is a risk factor for intracerebral hemorrhage (ICH) and worse outcomes following ICH. In this study, we examined the relationship between function, ICH, brain iron deposition, using quantitative susceptibility mapping (QSM) cerebral microbleeds (CMB) as intermediate biomarkers. We hypothesized that function an independent QSM/CMB, high QSM/CMB burden Methods: A retrospective cohort of spontaneous ICH non-ICH patients with CT/MR imaging was...
Measuring tools designed to objectively determine equine noseband tightness are inserted on the dorsal nasal planum in a rostro-caudal direction. The lateral aspect of horse's head has several areas where minimal soft tissue intervenes between skin and underlying bone, which makes them potentially useful sites for measuring tightness. One hundred horses were fitted with snaffle bridle cavesson, Swedish or dropped random order. each type was adjusted sequentially 2.0, 1.5, 1.0, 0.5 0.0...
Information describing forces applied to the horse are needed inform regulatory decisions regarding equine health and wellbeing. This study compares exerted beneath noseband headpiece of a snaffle bridle (SB) double (DB). Horses were fitted with same type SB DB. Forces measured by pressure mats under (nasal/mandibular) (occipital) force sensors inserted bilaterally between bit(s) reins. The was adjusted 2 finger-equivalents using tightness gauge. Data recorded for eleven high-level dressage...
Epibatidine, a newly discovered alkaloid from the skin of Dendrobatidae frogs, has structural similarities to nicotine. We examined effects epibatidine on cardiorespiratory function and ganglionic synaptic transmission. Superior cervical or splanchnic sympathetic nerve discharge (sSND) phrenic (PND) were recorded along with arterial pressure (AP) in urethane-anesthetized, paralyzed artificially ventilated rats. Epibatidine administered i.v. at low doses (0.5-2 micrograms/kg) produced...
Abstract Background Noseband adjustment should avoid discomfort and allow some jaw movement. Objectives To determine pressure beneath a cavesson noseband at five tightness levels during standing chewing. It was hypothesised that increased is associated with increases in nasal mandibular pressures while chewing, accompanied by eye temperature blink rate. Study design Experimental. Methods Eight highly‐trained dressage horses wore snaffle bridle their own bit. Pressure mats over the bones rami...
The horse-rider system is of great interest in understanding the mechanics involved optimising locomotor function and performance ridden horse. Adult riders (n=30) attending a rider conference volunteered to take part study. Riders were asked mimic riding position by positioning themselves symmetrically on their seat bones (ischial tuberosities) sitting (Pliance) pressure mat which was placed static platform. also even rein contact using reins with gauges attached solid wall. When satisfied...