A5043397075- Burn Injury Management and Outcomes
- Wound Healing and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Organ and Tissue Transplantation Research
- Injury Epidemiology and Prevention
- Reconstructive Facial Surgery Techniques
- Organ Donation and Transplantation
- Surgical Sutures and Adhesives
- Dermatologic Treatments and Research
- Disaster Response and Management
- Pressure Ulcer Prevention and Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Arrest and Resuscitation
- Laser Applications in Dentistry and Medicine
- Planarian Biology and Electrostimulation
- Traumatic Ocular and Foreign Body Injuries
- Restraint-Related Deaths
- Facial Nerve Paralysis Treatment and Research
- Head and Neck Surgical Oncology
- Body Contouring and Surgery
- Social Robot Interaction and HRI
- Pediatric Pain Management Techniques
- Diagnosis and Treatment of Venous Diseases
- Nonmelanoma Skin Cancer Studies
- Hernia repair and management
Universitat Autònoma de Barcelona
2016-2025
Vall d'Hebron Hospital Universitari
2016-2025
Vall d'Hebron Institut de Recerca
2013-2025
Hospital Sant Joan de Déu Barcelona
2025
Hebron University
2014-2024
Hospital Clínico Universitario Lozano Blesa
2001-2016
Instituto de Investigación Sanitaria Aragón
2016
Hospital Quirón Teknon
2009
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2009
Instituto Aragonés de Ciencias de la Salud
2008
Rates of survival after thermal injury have improved in the past two decades, and rates wound infections sepsis decreased during same period. Early excision has been advocated as one major factors, but its safety efficacy exact timing burn are still under debate. It was hypothesized that acute (in first 24 hours burning) would be superior to conservative treatment delayed preventing bacterial colonization invasion. Twenty consecutive patients with injuries were studied. Twelve underwent...
Objective To determine the effects of recombinant human insulin-like growth factor-1 (IGF-1) complexed with its principal binding protein, IGFBP-3, on skeletal muscle metabolism in severely burned children. Summary Background Data Severe burns are associated a persistent hypermetabolic response characterized by hyperdynamic circulation and severe catabolism wasting. Previous studies showed that nutritional support pharmacologic intervention anabolic agents such as hormone insulin abrogated...
Since 2005, 11 human face transplants have been performed. In each, varying amounts of tissue transplanted. Herein we report a "full" transplant including all intact aesthetic and functional units.On March 27, 2010, performed full transplant, the soft tissues part underlaying bony structure, at University Hospital Vall d'Hebron, Barcelona, Spain. The donor was 41-year-old male, who died from massive brain hemorrhage. recipient 30-year-old male with severe facial deformity caused by ballistic...
Partial-thickness burns in children have been treated for many years by daily, painful tubbing, washing, and cleansing of the burn wound, followed topical application antimicrobial creams. Pain impaired wound healing are main problems. We hypothesized that treatment second-degree with Biobrane is superior to treatment. Twenty pediatric patients were prospectively randomized two groups compare efficacy versus 1% silver sulfadiazine. The rest routine clinical protocols both groups. Demographic...
Trauma induces hypermetabolic responses that are characterized by the mobilization of all available substrates. The marked increase peripheral lipolysis after a burn can lead to development fatty liver, which has been associated with immunodepression and increased mortality.All autopsies pediatric patients between January 1988 1998 were reviewed. Patient demographics, hospital course, cause death, hepatic septic macroscopic microscopic findings recorded.Thirty-seven (4 +/- 1 years old)...
In 1994, the first Spanish study on patients with self-inflicted burns (SIB) was published, showing a prototypical profile of patient SIB: adult male, unmarried and, in 75% cases, psychiatric background. addition, SIB accounted for 1.98% total admissions Burns Unit between 1983 and 1991, lower percentage than other European studies. The present aims to replicate this work, updating comparing it current profile. We compared clinical socio-demographic characteristics 67 admitted during...
Early burn wound excision modulates the hypermetabolic response in severe pediatric injuries.Before-after trial.A 30-bed referral center a private, university-affiliated hospital.We studied 35 severely burned children who were divided into 2 groups. One group (n = 20) was treated with early within 24 hours after injury. The second 15) conservatively silver sulfadiazine other facilities for 5 days, and wounds surgically excised when patients admitted to our on day 6 Data compiled included...
The clinical significance of timely re-epithelialization is obvious in burn care, since delayed wound closure enhancing the risk site infection and extensive scarring. Topical treatments that accelerate healing are urgently needed to reduce these sequelae. Evidence from preliminary studies suggests betulin can different types wounds, including second degree burns split-thickness skin graft wounds. goal this combined study program consisting two randomized phase III trials parallel evaluate...
Psychrophilic bacteria, also known as cold-loving are microorganisms that thrive in extremely cold environments, typically at temperatures ranging from -5°C to 15°C. These bacteria found habitats such the deep ocean, polar regions, and high-altitude environments. Because of their unique ability survive function low temperatures, psychrophilic becoming increasingly important bioengineering biotechnology. Their potential future include enzyme production for cold-temperature industrial...
Background: Bromelain-based enzymatic debridement is a treatment for deep partial and full thickness burns. It painful procedure that requires anaesthesia techniques. However, there limited information on the best strategy to guarantee adequate pain control. Objective: To describe anaesthetic in patients treated with bromelain-based after burn injury. Methods: We performed an observational retrospective study by recording data from clinical records of burned debridement. Patients admitted...
Background/Objectives: Enzymatic debridement with bromelain is a treatment option for deep partial thickness and full burns. This procedure associated significant pain, necessitating the use of anesthesia techniques. However, there limited evidence on optimal strategy to achieve effective pain control. To detail anesthetic approach in patients undergoing bromelain-based enzymatic burn injuries. Methods: A retrospective observational study was conducted by analysing medical records treated...
Background: Donation after circulatory death (DCD) has emerged as a potential source of transplantable organs. To date, there have been no reports face procurement in AD, and “face first” with ex situ perfusion become the gold standard technique for obtaining facial allografts most centres. Objectives: We report case successful total kidney transplantation from 47-year-old male AD donor. Methods: Immediately confirmation death, “rapid recovery” was performed cannula placed ascending aorta...
Objective To assess the efficacy of cultured epidermal autografts (CEA) for closure burn wounds in pediatric patients with full-thickness burns more than 90% total body surface area. Summary Background Data Paucity donor sites massive makes use expanded skin paramount importance. CEA techniques have been used burned differing and controversial results. The true impact such remain uncertain. Methods Patients area treated between May 1988 1998 were studied. grafted compared conventional meshed...
Face transplantation is a viable reconstructive approach for severe craniofacial defects. Despite the evolution witnessed in field, ethical aspects, clinical and psychosocial implications, public perception, economic sustainability remain subject of debate unanswered questions. Furthermore, poor data reporting sharing, absence standardized metrics outcome evaluation, lack consensus definitions success failure have hampered development "transplantation culture" on global scale. We completed...