A5009831869- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Colorectal and Anal Carcinomas
- Chemotherapy-induced organ toxicity mitigation
- Ovarian cancer diagnosis and treatment
- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Cancer Diagnosis and Treatment
- Phonocardiography and Auscultation Techniques
- Cancer Risks and Factors
- Uterine Myomas and Treatments
- Ferroptosis and cancer prognosis
- Epigenetics and DNA Methylation
- Inflammatory Biomarkers in Disease Prognosis
- Maternal and Perinatal Health Interventions
- Immune Response and Inflammation
- IL-33, ST2, and ILC Pathways
- Pancreatic and Hepatic Oncology Research
- Chromatin Remodeling and Cancer
- Nutrition and Health in Aging
- Management of metastatic bone disease
- Childhood Cancer Survivors' Quality of Life
- Endometriosis Research and Treatment
- Inflammasome and immune disorders
Southern Medical University
2019-2024
Nanfang Hospital
2019-2024
First People's Hospital of Foshan
2021-2023
Sun Yat-sen University
2022-2023
Sun Yat-sen University Cancer Center
2022-2023
Fujian Medical University
2023
Gut microbiota has been reported to be disrupted by cisplatin, as well modulate chemotherapy toxicity. However, the precise role of intestinal in pathogenesis cisplatin hepatotoxicity remains unknown.We compared composition and function gut between mice treated with without using 16S rRNA gene sequencing via metabolomic analysis. For understanding causative relationship dysbiosis hepatotoxicity, antibiotics were administered deplete faecal transplantation (FMT) was performed before...
The study aimed to evaluate the accuracy of perineural invasion (PNI) diagnosis in cervical cancer, and analyze impact PNI on prognosis postoperative adjuvant treatment decisions for cancer.
Objective To assess the prognostic nutritional index (PNI) and quality of life (QOL) patients with cervical cancer (CC) who underwent radiotherapy chemotherapy to reveal effect PNI on QOL its value. Methods A total 138 CC in Second Affiliated Hospital Fujian Medical University from January 2020 October 2022 were selected as study subjects via convenient sampling. According cut-off value 48.8, they divided into a high-PNI group low-PNI group, two groups was compared. The Kaplan-Meier method...
The current study was designed to investigate the perinatal risk factors for low 1-min Apgar scores in term neonates. We retrospectively analyzed maternal and neonatal clinical data of 10,550 infants who were born through vaginal delivery from 37 weeks 0 days 41 6 single gestation January 2013 July 2018. Because score reflects status at birth, we (score <7) logistic regression. Among these neonates, 339 (3.2%) had scores. them, 321 (94.7%) admitted neonatology department further observation...
Abstract Objective This study aimed to identify patients with stage IB1‐IIA2 cervical cancer at low risk for lymph node metastasis (LNM) using preoperative magnetic resonance imaging (MRI) parameters. Methods Clinical and MRI data of who underwent radical surgery between 2010 2015 were retrospectively reviewed. was diagnosed according the 2009 International Federation Gynecology Obstetrics staging system. The low‐risk criteria LNM identified logistic regression analysis. performance analysis...
Early-stage cervical cancer rarely extends to the uterine corpus and invades serosal layer. Here, we present a case of extending then penetrating myometrium invade sigmoid colon. Transabdominal type C2 radical hysterectomy, bilateral salpingo-oopherectomy, pelvic lymphadenectomy, resection were performed. The patient underwent chemotherapy as she was unable tolerate chemoradiotherapy. She recovered well followed up for 14 months. Our report reveals that can be route tumor metastasis in cancer.
To explore the effects of bromine domain protein 4 (BRD4) inhibitor JQ1 on expression profile super-enhancer-related genes (SE-genes) in cervical cancer (CC) HeLa cells and construct a prognosis model to potential impact CC. Whole transcriptome sequencing technology was used detect changes gene profiles JQ1-treated control cells. Differentially expressed SE-genes were identified by matching via dbCoRC database Cistrome Data Browser (Cistrome DB). The differentially analyzed Cancer Genome...
We aimed to compare the prognosis of modified no-touch laparoscopic radical hysterectomy (MLRH) and (LRH) on survival in patients with early stage cervical cancer.The clinicopathological data IB1 IIA1 cancer, who underwent surgery between 2014 2019, were retrospectively reviewed. The 5-year disease-free (DFS) overall (OS) compared MLRH LRH groups using Kaplan-Meier method. Independent prognostic factors for DFS OS identified multivariate, forward, stepwise Cox proportional hazards regression...
Objective: This study aimed to identify a subset of patients with stage IA2 IIA2 cervical cancer who are at low risk lymph node metastasis (LNM) using pathological parameters including estrogen receptor alpha (ERα) and progesterone (PR). Methods: The clinical data underwent radical surgery between 2014 2015 were retrospectively reviewed. Immunohistochemical staining was used determine the expression ERα PR. A low-risk criterion for LNM identified logistic regression analysis, its performance...