A5100442905- Respiratory Support and Mechanisms
- Inflammasome and immune disorders
- Tea Polyphenols and Effects
- Phytochemicals and Antioxidant Activities
- Asthma and respiratory diseases
- Phytoestrogen effects and research
- Neonatal Respiratory Health Research
- Protein Hydrolysis and Bioactive Peptides
- Urological Disorders and Treatments
- Marine Sponges and Natural Products
- Neuroinflammation and Neurodegeneration Mechanisms
- Eosinophilic Disorders and Syndromes
- Microbial Natural Products and Biosynthesis
- Medicinal Plant Extracts Effects
- Anesthesia and Neurotoxicity Research
- Sarcoidosis and Beryllium Toxicity Research
- Calcium signaling and nucleotide metabolism
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Tryptophan and brain disorders
- Infant Nutrition and Health
- Pharmacological Effects of Natural Compounds
- Fungal Biology and Applications
- Urinary and Genital Oncology Studies
- Neonatal Health and Biochemistry
- Biochemical effects in animals
Anhui Medical University
2014-2025
Soochow University
2023-2025
Second Affiliated Hospital of Soochow University
2023-2025
First Affiliated Hospital of Anhui Medical University
2014-2025
Second Affiliated Hospital of Nanjing Medical University
2021-2024
Guangdong Pharmaceutical University
2024
Shenzhen Maternity and Child Healthcare Hospital
2024
Jiangsu University
2009-2024
Affiliated Hospital of Jiangsu University
2022-2024
Shanxi Provincial Cancer Hospital
2024
The antioxidant capacity of fermented soy whey (FSW) was investigated in order to find out their nutraceutical potential, and unfermented (USW) used as a control. FSW prepared using Lactobacillus plantarum B1–6 starter. effects fermentation on terms total phenolic content (TPC), activities DNA damage protection were investigated. USW determined by different standard methods. results showed extract compared possessed more TPC isoflavone aglycone contents, had higher ABTS radical scavenging...
The study aimed to evaluate the accuracy of perineural invasion (PNI) diagnosis in cervical cancer, and analyze impact PNI on prognosis postoperative adjuvant treatment decisions for cancer.
Abstract Background: Estrogen has been suggested to play a protective role against airway inflammations, such as asthma. In these processes, the inflammasome nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3 (NLRP3) partly accounts for activation of pro-inflammatory factors. The aim present study was investigate whether NLRP3 involved in effect estrogen allergic inflammation. Methods: An ovariectomy performed on female C57BL/6 mice; some were...
Abstract The highly transmissible severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has caused high rates of breakthrough infections in those previously vaccinated with ancestral strain disease 2019 (COVID-19) vaccines. Here, we demonstrate that a booster dose UB-612 vaccine candidate delivered 7–9 months after primary vaccination increased neutralizing antibody levels by 131-, 61-, and 49-fold against SARS-CoV-2 the BA.1 BA.2 variants, respectively. Based on...
Aim/Purpose of the study: Acute lung injury (ALI) is a severe respiratory disease with high mortality, mainly due to overactivated oxidative stress and subsequent pyroptosis. Mesencephalic astrocyte-derived neurotrophic factor (MANF), an inducible secretory endoplasmic reticulum (ER) protein, inhibits lipopolysaccharide (LPS)-induced acute (ALI). However, exact molecular mechanism remains unclear. Peroxiredoxin 6 (PRDX6), peroxidase dual enzymatic function, essential in regulating stress,...
Introduction: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a severe hypersensitivity reaction rarely documented in patients multiple myeloma (MM). Methods: In our retrospective study of 108 newly diagnosed MM (NDMM) from January 2021 to October 2023, we identified four cases DRESS. The clinical characteristics such as manifestations, laboratory results, treatment outcome were analyzed. Results: These presented fever, persistent recurrent, along widespread red rash...
Early-onset idiopathic scoliosis (EOIS) is a spinal deformity that develops before the age of 10 years with unknown etiology. Scoliosis can lead to respiratory muscle weakness and decreased motor function. Nevertheless, effects mild EOIS on pulmonary function functional exercise capacity remain poorly understood. Early detection crucial mitigate its impact children's health prevent progression. The aim this study was investigate characteristics in children identify influencing factors. 52...
Ulcerative colitis (UC), belonging to inflammatory bowel disease (IBD), is a chronic and relapsing disorder of the gastrointestinal tract, which has not been completely cured in patients so far. Valeriana jatamansi Chinese medicine used clinically treat "diarrhea," closely related UC. This study was elucidate therapeutic effects V. extract (VJE) on dextran sodium sulfate (DSS)-induced UC mice its underlying mechanism. In this work, VJE effectively ameliorates symptoms histopathological...
Background. Our colleagues have demonstrated an impressive therapeutic role of sevoflurane in a murine allergic airway inflammation model, but the mechanisms underlying this effect remain undefined. In study, we tried to investigate on resolution and assess whether NLRP3 or inflammasome is involved process. Methods. Female (C57BL/6) mice were sensitized challenged with ovalbumin (OVA). Then, some received MCC950 (10 mg/kg; i.p.) 3% sevoflurane. Total differential inflammatory cell numbers,...
Non-alcoholic steatohepatitis (NASH) is an inflammatory disorder that characterized by chronic activation of the hepatic response and subsequent liver damage. The regulation macrophage polarization in closely related to progression NASH. orphan nuclear receptor retinoic-acid-related α (RORα) Krüppel-like factor 4 (KLF4) are key regulators which promote macrophages toward M2 phenotype protect against NASH mice. Nobiletin (NOB), a natural polymethoxylated flavone, previously reported as RORα...
Depression associated with low plasma amyloid-β peptide 42 (Aβ42) leading to a high ratio of Aβ40/Aβ42, biomarker Alzheimer disease (AD), may represent unique depression subtype. The relationship between Aβ42 in and the major risk factor AD, apolipoprotein E4 (ApoE4), is unknown. With goal clarifying this relationship, we analyzed 1060 homebound elders ApoE characterization status cross-sectional study. Plasma Aβ40 were measured, cognition evaluated. In absence ApoE4 allele, depressed...
Unresolved inflammation underpins the pathogenesis of allergic airway diseases, such as asthma. Ketamine, accepted a promising therapy for resistant asthma, has been demonstrated to attenuate inflammation. However, anti-inflammatory mechanism by ketamine in this setting is largely unknown. We aimed investigate whether autophagy was involved protective effect on Female C57BL/6 mice were sensitized ovalbumin (OVA) and treated with at 25, 50, or 100 mg/kg prior OVA challenge. In model,...
Objective.—To compare the proportion of patients who prefer rizatriptan orally disintegrating tablet (ODT) 10‐mg to sumatriptan 50‐mg tablet. Background.—Migraineurs express treatment preference based on a variety attributes including speed pain relief and medication formulation. Rizatriptan ODT is an formulation rizatriptan, selective 5‐HT 1B/1D receptor agonist. This study was conducted determine patient between for acute migraine. Methods.—This multicenter, randomized, open‐label,...