Vikram V. Holla

ORCID: 0000-0002-3634-2219
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About
Contact & Profiles
Research Areas
  • Neurological disorders and treatments
  • Genetic Neurodegenerative Diseases
  • Parkinson's Disease Mechanisms and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Neurological diseases and metabolism
  • Autoimmune Neurological Disorders and Treatments
  • Mitochondrial Function and Pathology
  • Neurological and metabolic disorders
  • Glycogen Storage Diseases and Myoclonus
  • Genetics and Neurodevelopmental Disorders
  • RNA regulation and disease
  • Hereditary Neurological Disorders
  • Metabolism and Genetic Disorders
  • Autism Spectrum Disorder Research
  • Genomics and Rare Diseases
  • Peripheral Neuropathies and Disorders
  • Long-Term Effects of COVID-19
  • Infectious Encephalopathies and Encephalitis
  • Lysosomal Storage Disorders Research
  • Epilepsy research and treatment
  • Restless Legs Syndrome Research
  • Mosquito-borne diseases and control
  • Trigeminal Neuralgia and Treatments
  • Fetal and Pediatric Neurological Disorders
  • Facial Nerve Paralysis Treatment and Research

National Institute of Mental Health and Neurosciences
2019-2025

Universidade Federal da Integração Latino-Americana
2025

Creative Commons
2023

John Wiley & Sons (United States)
2021-2023

All India Institute of Medical Sciences Bhubaneswar
2022

King George's Medical University
2014-2021

Narayana Health
2020

University College of Medical Sciences
2012

Community Medical Center
1990

ABSTRACT: Background: Early-onset Parkinson’s disease (EOPD) refers to patients with (PD) whose age at onset is less than 50 years. Literature on the non-motor symptoms (NMS) in these very limited Indian context. We aimed study NMS EOPD and its impact quality of life (QoL). Methods: included 124 a mean between 21 45 years 60 healthy controls (HC). were assessed using validated scales, QoL domains evaluated PD QoL–39 scale (PDQ-39). Results: The was 37.33 ± 6.36 Majority male (66.12%)....

10.1017/cjn.2023.336 article EN Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2024-01-05

Infections are important treatable causes of secondary movement disorders (MD) that can have heterogeneous presentations. According to various studies, infection-related (IRMD) account for around 10-20% MD. Certain infections a predilection causing MD, and some MD phenomenologies, such as acute cerebellar ataxia opsoclonus-myoclonus-ataxia syndromes (OMAS), suggest strong possibility an underlying infectious cause. The pathophysiology is multifaceted, including direct neuronal damage due...

10.1016/j.prdoa.2024.100233 article EN cc-by-nc-nd Clinical Parkinsonism & Related Disorders 2024-01-01

The chronic and degenerative nature of Parkinson's' Disease (PD) can have significant impact on Persons with Parkinson's disease (PwPD). Non-pharmacological interventions contribute substantially to enhance their well-being. Dance movement therapy (DMT) is a psychotherapeutic intervention that involves coordinated movement, which improves Little known about the multidisciplinary professionals' perceptions DMT in PD management. This qualitative inquiry attempted explore perspectives...

10.1080/17432979.2024.2446159 article EN Body Movement and Dance in Psychotherapy 2025-01-03

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10.1017/cjn.2024.366 article EN Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2025-01-16

Introduction Parkinson’s disease (PD) is mainly characterized by motor symptoms including muscle rigidity, resting tremor and bradykinesia. However, the management of non-motor represent a relevant clinical challenger in PD. These include cognitive sleep disturbance there evidence that cannabinoids may alternative effective treatments for Methods Therefore, this study addressed effects oral treatment with cannabis extract on cognition, insomnia, daytime sleepiness six patients moderate The...

10.3389/fnhum.2024.1466438 article EN cc-by Frontiers in Human Neuroscience 2025-02-24

Abstract Background No objective biomarkers exist for diagnosing and classifying tremor syndromes. Objective The aim was to develop validate a deep learning (DL) algorithm tremors from hand‐drawn pen‐on‐paper spirals. Methods We recruited participants with dystonic (DT), essential (ET), plus (ETP), Parkinson's disease (PD), cerebellar ataxia (AT), healthy volunteers (HV). Participants drew free‐hand spirals on paper, which were used train DL based transfer using InceptionResNetV2 Keras...

10.1002/mds.30176 article EN Movement Disorders 2025-03-17

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10.1017/cjn.2025.50 article EN other-oa Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2025-03-19
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