A5051481137- Neonatal Respiratory Health Research
- Asthma and respiratory diseases
- Cystic Fibrosis Research Advances
- Respiratory viral infections research
- Ocular Diseases and Behçet’s Syndrome
- Food Allergy and Anaphylaxis Research
- Ureteral procedures and complications
- Congenital Diaphragmatic Hernia Studies
- Transplantation: Methods and Outcomes
- Yersinia bacterium, plague, ectoparasites research
- Tracheal and airway disorders
- Contact Dermatitis and Allergies
- Neonatal Health and Biochemistry
- Allergic Rhinitis and Sensitization
- Antifungal resistance and susceptibility
- Immunodeficiency and Autoimmune Disorders
- Retinal and Optic Conditions
- Ion Transport and Channel Regulation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Systemic Lupus Erythematosus Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pediatric Urology and Nephrology Studies
- Legionella and Acanthamoeba research
- Pharmaceutical studies and practices
- Connexins and lens biology
Children's Hospital
2016-2024
Faculté de médecine de Tunis
2022-2024
Tunis University
2022-2024
Tunis El Manar University
2017-2024
Hôpital d'Enfants
2014-2024
Hôpital Charles-Nicolle
2022
King Fahd Medical City
2020-2021
Hôpital La Rabta
2021
Hôpital Mongi Slim
2020
Hopital Universitaire Hedi Chaker
2010-2016
Candida albicans chronically colonizes the respiratory tract of patients with Cystic Fibrosis (CF). It competes CF-associated pathogens (e.g. Pseudomonas aeruginosa) and contributes to disease severity. We hypothesize that C. undergoes specific adaptation mechanisms explain its persistence in CF lung environment. To identify underlying genetic phenotypic determinants, we serially recovered 146 clinical isolates over a period 30 months from sputum 25 antifungal-naive patients. Multilocus...
Objective: Our study aimed at assessing the role of flexible bronchoscopy (FB) in improving diagnosis and management children’s respiratory conditions pediatric unit FB, newly created unique Tunisia.Methods: Retrospective including all FB achieved our from 2009 to 2014.Results: We performed 365 333 patients aged 46 months on average (1 month - 15 years), often under conscious anesthesia (81.6%). was for diagnostic purposes 341 cases therapeutic 24 cases. Eight anatomical abnormalities were...
Aim: To establish a preliminary national report on clinical and genetic features of cystic fibrosis (CF) in Tunisian children as first measure for better health care organization.
 Methods: All with CF diagnosed by positive sweat tests between 1996 2015 children’s departments university hospitals were included. Data was recorded at diagnosis during the follow-up from patients’ medical records.
 Results: In 12 departments, 123 collected. The median age 5 months diag- nosis delay 3...
Coronavirus disease 2019 (COVID-19) is a zoonosis that emerged in China December 2019. Understanding the clinical presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and prognosis children major issue. Children often present mild symptoms, some forms require pediatric intensive care, with cases fatal prognosis. We aimed to describe novel children, including patient characteristics, clinical, laboratory, imaging findings, as well management outcomes. Our...
Introduction: Parents’ knowledge is an integral part of healthcare quality, impacting treatment adherence, patient loyalty and utilisation in pediatric asthma. Parental particularly crucial as parents influence decision-making for their child’s healthcare. Aim: To assess parents' perceptions children's asthma to identify areas weakness therapeutic education. Methods: This transversal survey study based on validated translated self-administered questionnaire (Arabic AAKQ). The was conducted 2...
The ingestion of foreign body (FB) is a common problem in paediatrics. Children are curious by nature and tend to explore environment inserting objects into their mouths. To update our epidemiological clinical data adapt management order limit morbidity associated with this fairly frequent accidental pathology. Retrospective descriptive study including children aged less than 15 years, hospitalized the Children's Medicine Department B Tunis Hospital from 1 January 2016 31 December 2021...
The incapacity to synthesize certain components of pulmonary surfactant causes a heterogeneous group rare respiratory diseases called genetic disorders dysfunction. We report female full-term infant with neonatal distress early onset due inherited SP-B deficiency. failed oxygen weaning at multiple trials. Chest computed tomography was performed on the 29th day life revealing ground-glass opacities, regular interlobular septal thickening and fine reticulations. Analysis genomic DNA showed...
Pseudo-Bartter syndrome (PBS) describes an uncommon complication of cystic fibrosis leading to hypochloraemic, hypokalaemic metabolic alkalosis. PBS as the sole manifestation in children is extremely rare and has never been described patients carrying 5T variant. We report a clinical, biochemical genetic study four year-old boy presenting pseudo-Bartter fibrosis. All 27 exons flanking intron regions CFTR gene were analysed by PCR direct sequencing. Direct sequencing was also used analyse...
Introduction: Mediastinal teratomas are rare in children. Nevertheless, they represent the most frequent mediastinal germ cell tumor. Most often, discovered incidentally older children or adolescents on chest X-ray. There other signs of discovery but less frequent: pain, hemoptysis and compression. Rupture into pleural space, pericardium tracheobronchial tree exceptional.
 Case presentation: We report case 7-years old girl admitted for pain. The x-ray showed a mass with calcifications...