Malissa Mulkey

ORCID: 0000-0002-3686-9539
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About
Contact & Profiles
Research Areas
  • Intensive Care Unit Cognitive Disorders
  • Anesthesia and Sedative Agents
  • Anesthesia and Neurotoxicity Research
  • Family and Patient Care in Intensive Care Units
  • Cardiac Arrest and Resuscitation
  • Respiratory Support and Mechanisms
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Healthcare Decision-Making and Restraints
  • Dementia and Cognitive Impairment Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Health and Lifestyle Studies
  • Healthcare Policy and Management
  • Emergency and Acute Care Studies
  • Sepsis Diagnosis and Treatment
  • Alzheimer's disease research and treatments
  • Mental Health and Psychiatry
  • Quality and Safety in Healthcare
  • Stroke Rehabilitation and Recovery
  • Nursing Diagnosis and Documentation
  • Long-Term Effects of COVID-19
  • Cardiovascular Health and Risk Factors
  • Workplace Violence and Bullying
  • Amyotrophic Lateral Sclerosis Research
  • Primary Care and Health Outcomes
  • Acute Ischemic Stroke Management

University of South Carolina
2022-2024

University of Milano-Bicocca
2024

Indiana University – Purdue University Indianapolis
2020-2023

Rex Hospital
2021-2023

RELX Group (United States)
2023

University School
2023

Indiana University
2023

National Institute of Nursing Research
2022

Louisburg College
2022

Weatherford College
2021

To determine if an early mobilization protocol increased mobility and improved clinical psychological outcomes. Currently, there is minimal research on the effects of in patients with primary neurologic injury.Prospective, two-group pre/post comparative design data collection 4 months pre- postintervention a 4-month run-in period.Twenty-two-bed ICU 1,200-bed urban, quaternary-care, academic hospital Northeast Ohio.Critically ill injury admitted to ICU.An program included progressive...

10.1097/ccm.0000000000000787 article EN Critical Care Medicine 2014-12-17

Delirium is an acute brain dysfunction associated with increased risk of mortality and future dementia. To describe the prevalence clinically documented delirium in United States on World Awareness Day 2023. This a sub-analysis prospective, cross-sectional, online, international survey. All health care settings were eligible, exception operating rooms outpatient clinics. Health clinicians, administrators, researchers completed The primary outcome was at 8:00 a.m. p.m. March 15, Secondary...

10.1016/j.jaclp.2024.06.005 article EN cc-by Journal of the Academy of Consultation-Liaison Psychiatry 2024-06-28

Abstract As many as 80% of critically ill patients develop delirium increasing the need for institutionalization and higher morbidity mortality. Clinicians detect less than 40% when using a validated screening tool. EEG is criterion standard but resource intensive thus not feasible widespread monitoring. This study evaluated use limited-lead rapid-response supervised deep learning methods with vision transformer to predict delirium. proof-of-concept used prospective design evaluate device...

10.1038/s41598-023-35004-y article EN cc-by Scientific Reports 2023-05-16
Alice Margherita Ornago Elena Pinardi Chukwuma Okoye Paolo Mazzola María Cristina Ferrara and 95 more Alberto Finazzi Peter Nydahl Rebecca von Haken Heidi Lindroth Keibun Liu Alessandro Morandi Giuseppe Bellelli Adela Goldberg Gideon A. Caplan Magdalena Hoffmann Ricardo Kenji Nawa Thiago H. Silva Roberta Esteves Vieira de Castro Karla D. Krewulak Tanya Mailhot Kirsten M. Fiest Marie Oexenbull Tej Pandya Metaxia Papanikolaou Julie Benbenishty Shelly Asheknazy Mohan Gurjar Suzanne Timmons Chi Ryang Chung Muhammed Elhadi Mark van den Boogaard Hilde Wøien Maria Carolina Paulino Gabi Heras Abdullah Alhammad Dejan Marković Yie Hui Lau Terry Quinn Gabi Heras Carola Giménez-Esparza Vich Marie‐Madlen Jeitziner Matthias Thomas Exl Bronagh Blackwood Esther S. Oh Mikita Fuchita K. Maya Kimberly Smith Tru Brynes Jessica Palakashappa Seb Cotton Breanna Hetland Natalie S. McAndrew Malissa Mulkey Clara Agostino Yanely Sarduy Alonso Ilaria Bandera Costanza Berti Ceroni Filippo Binda Daniela Mari Maria-Cristina Bragaglia Enrico Brunetti Luca Bucciarelli Stefano Cacciatore Monica Cadei Gianni Casella Martina Cavara Incoronata Chiusolo Antonio Ciambrone Giulia Clericò Alessandra Coin Marika Colacicco Alessandro Di Risio Valter Favero Paola Claudia Fazio Rosa Filippelli Luigi Francioni Alessandro Galazzi Barbara Gamba Giordana Gava Simona Gentile E Giovannini Barbara Guadi Mary Jane Isidro Angela Iurlaro Maria Legierska Silvia LoMele V Maniscalco Michela Marca Valentina Martella Claudia Massaro Marialaura Matacena Elena Merli Giuseppina Migliorino Alessandro Monesi Valeria Nativio Giulia Principato Daniela Quattrocchi Daniela Perelli Ercolini Sabina Perelli Ercolini Francesca Paternoster

Abstract Purpose Delirium, a common medical emergency among hospitalized patients, requires effective detection and management protocols. This study aims to evaluate the delirium point prevalence its across Italian hospitals, categorized by literacy levels. Additionally, it seeks identify prevailing barriers future priorities in practice research. Methods We analyzed data from World Delirium Awareness Day (WDAD) on March 15th, 2023, collected participating clinicians hospitals. High (HL) was...

10.1007/s41999-024-01019-5 article EN cc-by European Geriatric Medicine 2024-07-18

Nurses are expected to participate in research and scholarly inquiry; despite ongoing attempts, the practice-research gap continues be fraught with significant barriers. System strategies have not addressed concerns at individual nurse level. Given implications on quality safety, focusing identification of should an important focus attention for nursing leaders researchers. This article seeks describe barriers, potential solutions, leaders.

10.1097/nnd.0000000000000732 article EN Journal for Nurses in Professional Development 2021-03-29

Post-intensive care syndrome is a collection of symptoms that more than half patients who survive critical illness, and their family caregivers, experience after the illness. Those include weakness/ fatigue, sleep disturbances/insomnia, cognitive dysfunction, posttraumatic stress disorder, other mental health conditions, lack effective coping strategies.To minimize risk patient developing post-intensive syndrome, intensive unit nurses must adopt practices reduce severity disability optimize...

10.4037/ccn2022374 article EN Critical Care Nurse 2022-08-01

Patients treated in a neuroscience intensive care unit (NICU) are often viewed as too sick to tolerate physical activity. In this study, mobility status NICU was assessed, and factors outcomes associated with were examined.Using prospective design, daily status, medical history, demographics, Acute Physiology Chronic Health Evaluation (APACHE) III score, clinical collected by records database review. Depression, anxiety, hostility assessed before discharge. Analyses included comparative...

10.1097/jnn.0000000000000053 article EN Journal of Neuroscience Nursing 2014-05-05

Abstract Delirium is an acute disorder affecting up to 80% of intensive care unit (ICU) patients. It associated with a 10‐fold increase in cognitive impairment, triples the rate in‐hospital mortality, and costs $164 billion annually. acutely affects attention global function fluctuating symptoms caused by underlying organic etiologies. Early detection crucial because longer patient experiences delirium worse it becomes harder treat. Currently, identification through intermittent clinical...

10.1002/nur.21953 article EN Research in Nursing & Health 2019-05-30

ABSTRACT In 2018, the Society of Critical Care Medicine published Pain Agitation Delirium Immobility and Sleep Disruption guidelines that recommend protocol assessment-based pain sedation management. Since publication these guidelines, multiple studies meta-analyses have been conducted comparing sedative options in Intensive Unit (ICU) setting including dexmedetomidine propofol. Sedatives are on a continuum when it comes to delirium risk. Propofol, like benzodiazepines, causes changes sleep...

10.1097/jxx.0000000000000364 article EN Journal of the American Association of Nurse Practitioners 2020-01-16

Abstract Background Studies suggest Angiotensin‐Converting Enzyme inhibitors (ACEI) and Angiotensin Receptor Blockers (ARB) may slow the decline of memory function in individuals with mild to moderate Alzheimer's disease by regulating migroglial activation oxidative stress within brain's reticular activating system. Therefore, we evaluated relationship between delirium prevalence being prescribed ACEI ARB participants admitted intensive care units (ICU). Methods A secondary analysis data...

10.1111/jgs.18285 article EN cc-by-nc Journal of the American Geriatrics Society 2023-03-11

Topic Assessing functional cognition is a critical need for intensive care unit survivors transitioning to another level of care. Clinical Relevance Up 62% patients discharged from an have significant cognitive impairment that not associated with severity illness, number comorbidities, or length hospital stay. For more than 20 years, researchers published array potentially effective interventions, including case management, patient and informal caregiver education, home health services....

10.4037/ccn2023718 article EN Critical Care Nurse 2023-04-01

Patients with alterations in level of consciousness are among the most difficult to assess, so knowledge how assess these patients is important for tracking trends and identifying changes. This article discusses methods used admitted an altered describes neurological assessment potential causes consciousness. Identifying understanding certain examination findings enable faster recognition intervention life-threatening events, directly impacting outcomes neurologically compromised individuals.

10.4037/ccn2023449 article EN Critical Care Nurse 2023-08-01

Abstract Delirium is defined as a mental disorder characterized by an abnormal state of cognition and awareness. associated with annual cost $350 billion between the United States Europe. Approximately 80% delirium cases are either not identified or misdiagnosed. Older adults have highest incidence due to consequences aging. Hypoactive “quite delirium” most common subtype experienced older adults. delirium, difficult recognize has worse outcomes than other subtypes. If detected, symptoms...

10.21307/ajon-2017-015 article EN cc-by-nc-nd Deleted Journal 2019-03-18

Fronto-temporal dementia, also known as fronto-temporal lobular degeneration, is the second most common form of early-onset dementia with a prevalence equal to Alzheimer's dementia. Behavioural variant primarily involves frontal and temporal lobes brain. Myelination nerve fibres in these areas allow for highly synchronized action potential timing. Diagnosis often significantly delayed because symptoms are insidious appear personality behavioural changes such lack inhibition, apathy,...

10.12968/bjcn.2019.24.11.544 article EN British Journal of Community Nursing 2019-11-01

Caring for patients experiencing alcohol withdrawal syndrome can be challenging. Patients 65 and older are at increased risk related complications. The higher prevalence of co-morbidities, including cognitive impairment, longer drinking history greater sensitivity to treatment the result decreased ability brain adapt stressors such as illness, trauma, or surgery.Symptoms may appear earlier from last drink present with a wide range symptoms. most effective interventions require high-quality...

10.1097/jnn.0000000000000543 article EN Journal of Neuroscience Nursing 2020-10-03

Delirium-related biochemical derangements lead to electrical changes that can be detected in electroencephalographic (EEG) patterns followed by behavioral signs and symptoms. Studies using limited EEG show a large difference between patients with without delirium while discriminating from other causes. Handheld rapid devices may capable of detecting before symptom onset, thus providing an objective physiological method detect when it is most amenable interventions.The aim this study was...

10.1097/dcc.0000000000000502 article EN Dimensions of Critical Care Nursing 2021-11-24

Negative behaviors often are directed toward nursing staff in verbal or physical assaults. Nursing on non-psychiatric units may not be prepared to manage such situations and need additional support. Behavioral Emergency Response Teams (BERTs) have been effective supporting faced with patients exhibiting these behaviors.

10.62116/msj.2021.30.4.229 article EN Medsurg nursing 2021-01-01

Agitation is a symptom of many medical and psychiatric disorders that can manifest along spectrum severity. often delays treatment onset, potentially impacting morbidity mortality, may require emergency interventions. Management acute agitation centers around three main goals: early recognition the underlying etiology, rapid control behavior, prevention harm to patient personnel. Nurses should increase use validated techniques, including frequent sufficient reality orientation, validation...

10.62116/msj.2021.30.1.9 article EN Medsurg nursing 2021-01-01
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