Compressed sensing (CS) is a promising method for accelerating cardiac perfusion MRI to achieve clinically acceptable image quality with high spatial resolution (1.6 × 1.6 8 mm 3 ) and extensive myocardial coverage (6–8 slices per heartbeat). A major disadvantage of CS its relatively lengthy processing time (~8 min slice 64 frames using graphics unit), thereby making it impractical clinical translation. The purpose this study was implement test whether an reconstruction pipeline including...

Purpose To achieve ultra-high temporal resolution (approximately 20 msec) in free-breathing, real-time cardiac cine MRI using golden-angle radial sparse parallel (GRASP) reconstruction amplified with view sharing (VS) and k-space–weighted image contrast (KWIC) filtering. Materials Methods Fourteen pediatric patients congenital heart disease (mean age [SD], 9 years ± 2; 13 male) 10 adult arrhythmia age, 62 8; nine who underwent both standard breath-hold free-breathing GRASP were...

Abstract Purpose To develop a highly‐accelerated, real‐time phase contrast (rtPC) MRI pulse sequence with 40 fps frame rate (25 ms effective temporal resolution). Methods Highly‐accelerated golden‐angle radial sparse parallel (GRASP) over regularization may result in blurring, which turn causes underestimation of peak velocity. Thus, we amplified GRASP performance by synergistically combining view‐sharing (VS) and k ‐space weighted image (KWIC) filtering. In 17 pediatric patients congenital...

To develop an accelerated wideband cardiac perfusion pulse sequence and test whether it can produce diagnostically acceptable image quality be used to reliably quantify myocardial blood flow (MBF) in patients with a implantable electronic device (CIED).A fivefold-accelerated was developed using compressed sensing sample one arterial input function plane three (MP) planes per heartbeat CIED heart rates as high 102 beats minute. Resting scans were performed 10 no control group. Two clinical...

Left atrial volume and function are associated with recurrence of paroxysmal fibrillation (AF) after radiofrequency ablation. A relationship between left mechanical dyssynchrony AF is presently unclear. The aim this study was to investigate whether volume, function, were in patients normal ventricular or mildly enlarged atrium, if assessed by the Real-time three-dimensional echocardiography (3DE).We included 88 who had their first pulmonary vein isolation. There 67 without 21 3DE performed...

A recent study reported that diffuse left ventricular (LV) fibrosis is a predictor of atrial fibrillation (AF) recurrence following catheter ablation, by measuring postcontrast cardiac T

Purpose To determine whether left ventricular (LV) extracellular volume (ECV) expansion is associated with atrial fibrillation (AF) or AF-mediated LV systolic dysfunction (LVSD) while minimizing the influence of biologic and imaging methodologic confounders. Materials Methods This study examined prevalence ECV in 137 patients AF (mean age, 62 years ± 11 [standard deviation]; 92 male 45 female patients; 83 paroxysmal 54 persistent) who underwent preablation cardiovascular MRI. Biologic...

Conventional thoracic non-contrast magnetic resonance angiography (NC-MRA) often produces suboptimal image quality in pediatric patients with congenital heart disease (CHD) and results lengthy scan times. We recently developed a NC-MRA pulse sequence using stack-of-stars k-space sampling pattern XD-GRASP reconstruction evaluated its performance adults. In this study, we sought to improve our by incorporating view-sharing (VS) weighted contrast (KWIC) filtering reduce blurring, which is...

Late gadolinium enhancement (LGE) is the clinical standard for assessment of myocardial scarring. Current limitations LGE are lengthy scan time, sensitivity to arrhythmia and/or dyspnea, and reliance optimal inversion time (TI), which may be difficult identify patients with subendocardial We propose a free-breathing, single-short, multi-TI approach address aforementioned challenges. Our results show that GRASP-Pro reconstruction view-sharing (VS) k-space weighted image contrast (KWIC)...

Highly-accelerated real-time cine MRI is a rapid technique that particularly useful for patients with arrhythmia, dyspnea, and/or pediatric who may not be able to follow breath-hold instructions. Incorporating view-sharing (VS) and k-space weighted image contrast (KWIC) filtering into compressed sensing (CS) reconstruction framework improves spatio-temporal resolution in our 32-fold accelerated free-breathing using radial sampling. Resulting biventricular volumetric parameters are relatively...

Motivation: While simultaneous multi-slice (SMS) excitation has been proposed to increase the myocardial coverage for cardiac perfusion MRI, its influence on quantification of blood flow (MBF) not evaluated. Goal(s): To determine whether SMS with multiband factor two preserves accuracy in MBF compared corresponding MRI single-slice excitation. Approach: We prospectively enrolled six patients and performed standard back-to-back calculated arterial input function (AIF) resting MBF. Results:...

Motivation: Little is known about the right ventricular (RV) perfusion reserve in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and whether thromboendarterectomy (PTE) surgery improves RV perfusion. Goal(s): This study sought to assess PTE CTEPH correlates invasive hemodynamics. Approach: We prospectively enrolled 6 subjects undergoing PTE, performed stress-rest MRI heart catheterization, calculated myocardial pre post PTE. Results: improved hemodynamics, may serve as a...

Motivation: Radial k-space sampling is preferred over cartesian due to its many advantages. One major drawback of radial the streaking artifacts that arise from non-linear gradients peripheral FOV. Goal(s): The goal this study reduce streaky artifacts. Approach: We developed an algorithm aims detect coils based on post-processing coils’ images and then remove these for a cleaner image. Results: Our results show proposed method precisely predicts improves appearance in CS...

Motivation: Unrolled networks (UN) achieve state-of-the-art performance in undersampled dynamic MRI reconstruction but suffer from long training times and extensive GPU memory cost. Goal(s): To apply an implicit strategy for UNs (IMUNNE) combination with transfer learning to develop efficient versatile technique accelerated cardiac MRI. Approach: We compare IMUNNE a complex denoiser U-Net end-to-end UN on three different highly datasets. Results: For all datasets, we observed that: (1) both...

Abstract While single‐shot late gadolinium enhancement (LGE) is useful for imaging patients with arrhythmia and/or dyspnea, it produces low spatial resolution. One approach to improve resolution accelerate data acquisition using compressed sensing (CS). Our previous work described a single‐shot, multi‐inversion time (TI) LGE pulse sequence radial k ‐space sampling and CS, but over‐regularization resulted in significant image blurring that muted the benefits of acceleration. The purpose...

Purpose The purpose of this study was to determine an optimal saturation‐recovery time (TS) for minimizing the underestimation arterial input function (AIF) in quantitative cardiac perfusion MRI without multiple gadolinium injections per subject. Methods We scanned 18 subjects (mean age = 59 ± 14 years, 9/9 males/females) acquire resting data and 1 additional subject (age 38 male) obtain stress‐rest using a 5‐fold accelerated pulse sequence with radial k‐space sampling applied weighted image...

Purpose To develop and evaluate a flexible, Bloch‐equation based framework for retrospective correction to the arterial input function (AIF) obtained with quantitative cardiac perfusion pulse sequences. Methods Our initially calculates gadolinium concentration [Gd] on T 1 measurements alone. Next, is estimated from this initial calculation of while assuming fast water exchange using literature native 2 static magnetic field variation (ΔB 0 ) values. Finally, recalculated after performing...

Motion correction (MoCo) is an important pre-processing step for pixel-by-pixel myocardial blood flow (MBF) quantification from cardiac perfusion MRI. It may also improve throughput of visual evaluation images. One commonly used method MoCo optical (OF), which requires a moderate level computational demand. In this study, we sought to perform rapid respiratory motion on images using deep learning (DL). Our results show that the proposed DL performs 418-times faster than reference OF approach...

This study evaluates visual scores of image quality (conspicuity, artifact, noise; Likert scale 1[worst]-5[best], 3 acceptable) produced by a wideband cardiac perfusion sequence in patients with CIED and standard matching non-device the setting vasodilated stress imaging. The median conspicuity were not significantly different between (4) (4). While artifact score was worse for than (5), it above acceptable cutoff. noise better standard. Our produces diagnostically patients.

Introduction: This study seeks to determine whether bi-ventricular myocardial perfusion reserve (MPR) is reduced in patients with chronic thromboembolic pulmonary hypertension (CTEPH) compared a control group using quantitative MRI. Methods: We prospectively enrolled 4 CTEPH (55±14 years, males) and performed stress-rest (10 min apart) protocol our 5-fold accelerated radial sequence. In one patient, we repeated acquisition following thromboendarterectomy (PTE). As group, retrospectively...