A5101694227- Cardiac Arrest and Resuscitation
- Acute Myocardial Infarction Research
- Cardiac Ischemia and Reperfusion
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Anesthesia and Neurotoxicity Research
- Sepsis Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Thermal Regulation in Medicine
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Traumatic Brain Injury and Neurovascular Disturbances
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Anesthesia and Pain Management
- Angiogenesis and VEGF in Cancer
- Cardiac Valve Diseases and Treatments
- Simulation-Based Education in Healthcare
- Apelin-related biomedical research
- Macrophage Migration Inhibitory Factor
- Neonatal and fetal brain pathology
- Infectious Aortic and Vascular Conditions
- Online and Blended Learning
Women's Hospital, School of Medicine, Zhejiang University
2025
The First Affiliated Hospital, Sun Yat-sen University
2013-2024
Sun Yat-sen University
2013-2024
Changzhou University
2024
Guangzhou Medical University
2008-2022
Third Affiliated Hospital of Guangzhou Medical University
2008-2022
First Affiliated Hospital of Anhui Medical University
2017
Anhui Medical University
2017
Key Laboratory of Guangdong Province
2015
Beijing Chao-Yang Hospital
2012
Supervised Teaching Clinics (STCs) have emerged as an innovative approach to medical education, particularly in specialties like gynecology, where hands-on experience is crucial. Traditional clinical rotations often leave students passive roles, limiting their active participation and the development of essential skills. This study aimed evaluate impact STCs on competencies professional within a gynecological clinic, comparing outcomes with those traditional clinic shadowing. A total 144...
Tight junctions (TJs) are a critical component in maintaining the intestinal mucosal barrier function and gastrointestinal health of animals. Gut dysfunction contributes to initiation development sepsis which induces an uncontrollable systemic inflammatory response gives rise life‑threatening clinical conditions. Excretory‑secretary antigens from Trichimella spiralis (T. spiralis) have been reported protect mouse model, however mechanism remains be elucidated. Mice were treated with...
Dexmedetomidine (DEX) is an α 2-adrenergic agonist. It decreases the levels of norepinephrine release, resulting in a reduction postsynaptic adrenergic activity. In present study, effects DEX on postpartum bleeding-induced multiple organ dysfunction syndrome (BMODS) were studied rats which BMODS was induced by combination hypotension and clamping superior mesenteric artery. We evaluated role dexmedetomidine cytokine release during rats. summary, study demonstrated that administration reduced...
Abstract Background Atherosclerosis, the underlying cause of majority cardiovascular diseases, is a lipid-driven, inflammatory disease large arteries. Atherosclerotic (ASCVD) threatens human lives due to high morbidity and mortality. Many studies have demonstrated that atherosclerosis accelerated via activation NLRP3 inflammasome. The inflammasome plays critical role in development vascular inflammation atherosclerosis. In atherosclerotic plaques, excessive generation reactive oxygen species...
Abstract Background: Cost-impact models have indicated that in the USA, use of antibiotic stewardship protocols based on procalcitonin (PCT) levels for patients with suspected acute respiratory tract infection results cost savings. Our objective was to assess impact adopting PCT testing among infections (ARI) from perspective a typical hospital system urban China. Methods: To conduct an economic evaluation versus usual care we built cost-impact model previously published patient-level...
To explore the correlation between a septal angle measured on computed tomographic pulmonary angiography (CTPA) and vascular resistance (PVR) determined by right heart catheterization in patients with chronic thromboembolic hypertension (CTEPH).Eighty-six CTEPH (54 men, mean age: 53.08±12.43 y) were retrospectively reviewed, 86 sex-matched age-matched individuals without artery embolism used as control group. All underwent CTPA before catheterization. Septal was transverse images...
Urapidil is putatively effective for patients with hypertension and acute heart failure, although randomized controlled trials thereon are lacking. We investigated the efficacy safety of intravenous urapidil relative to that nitroglycerin in older failure a trial.Patients (>60 y) were randomly assigned receive (n=89) or (n=91) 7 days. Hemodynamic parameters, cardiac function, outcomes compared.Patients group had significantly lower mean systolic blood pressure (110.1±6.5 mm Hg) than those...
OBJECTIVE:The role of Ulinastatin in neuronal injury after cardiopulmonary resuscitation has not been elucidated.We aim to evaluate the effects on inflammation, oxidation, and cerebral cortex resuscitation.METHODS: Ventricular fibrillation was induced 76 adult male Wistar rats for 6 min, which initiated.After spontaneous circulation returned, were split into two groups: 100,000 unit/kg group or PBS-treated control group.Blood samples obtained compared at 2, 4, 8 h return circulation.The...
ObjectiveTo evaluate the clinical characteristics of acute pancreatitis (AP) concomitant with diabetic ketoacidosis (DKA) in a cohort from South China and identify factors associated early detection DKA AP patients.MethodsInpatient medical records were retrospectively reviewed.ResultsForty-eight patients enrolled this study. The results indicated that comorbidity history diabetes mellitus mental status not alert on admission patients. Compared without DKA, showed significantly higher rates...
Background. Sepsis-induced cardiomyopathy (SIC) is a sort of severe disease in the intensive care unit. This research focuses on exploring influence miR-340-5p SIC and its specific mechanism. Methods. Mice were administered with lipopolysaccharide (LPS) to construct animal model. intramyocardially injected Adenoassociated Virus- (AAV-) 9 containing precursor make overexpression myocardium. The expression level myocardial was evaluated by qRT-PCR. cardiac function measured echocardiography,...
The problem of wellbore leakage is a key challenge in the petroleum industry, limiting drilling progress and increasing costs. Plugging agents play role repairing leaks fractures; however, traditional plugging materials generally have low mechanical strength, poor adaptability to permeable strata, limited water absorption expansion capabilities, temperature salt resistance. To address these limitations, pioneering polyacrylic acid-polyacrylamide (PAA/PAM) double-network hydrogel was...
Dexmedetomidine has significant neuroprotective effects. However, whether its protective effects can reduce neurotoxicity caused by isoflurane in fetal brain during the second trimester of pregnancy remains unclear. In this study, timed-pregnancy rats at gestational day 14 spontaneously inhaled 1.5% for 4 hours, and were intraperitoneally injected with dexmedetomidine dosages 5, 10, 20, 20 μg/kg 15 minutes before inhalation after 2 hours. Our results demonstrate that hours inhaling...
YKL-40 is a novel inflammatory protein. Elevated serum levels of have been reported in patients with atherosclerosis and other cardiovascular diseases, but the circulating profile cerebrovascular disease has less investigated. This prospective observational study aimed to determine different subtypes severities disease. Eighty acute ischemic stroke, 30 hemorrhagic 15 transient attack (TIA) 18 age- gender-matched healthy control subjects were recruited. Blood was sampled. Serum measured by...
Intestinal ischemia-reperfusion (I/R) injury is a devastating complication when the blood supply reflowed in ischemic organs. Gastrin has critical function regulating acid secretion, proliferation, and differentiation gastric mucosa. We aimed to determine whether gastrin an effect on intestinal I/R damage. was induced by 60-min occlusion of superior mesenteric artery followed reperfusion, rats were be hypergastrinemic pretreated with omeprazole or directly injected gastrin. Some...
The aim of this study was to investigate the role miR-410 in regulating proliferation and apoptosis pediatric acute lymphoblastic leukemia (ALL) cells explore possible underlying mechanism.The expression level ALL cases detected by real-time fluorescence quantitative polymerase chain reaction (qRT-PCR). Luciferase reporter gene assay performed evaluate interaction between FKBP5. MTT colony formation were used determine effect on ability cells. cell measured Annexin V-fluorescein...