A5073006277- Extraction and Separation Processes
- Radioactive element chemistry and processing
- Cytokine Signaling Pathways and Interactions
- Chemical Synthesis and Characterization
- Heart Rate Variability and Autonomic Control
- Cancer-related molecular mechanisms research
- Asthma and respiratory diseases
- RNA modifications and cancer
- MicroRNA in disease regulation
- Cancer-related gene regulation
- Phytochemical compounds biological activities
- Cancer Mechanisms and Therapy
- Membrane-based Ion Separation Techniques
- Circular RNAs in diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- HVDC Systems and Fault Protection
Fujian Provincial Cancer Hospital
2024
Fujian Medical University
2024
Central South University
2020-2024
Third Xiangya Hospital
2020-2024
East China Normal University
2020
Abstract N 6 -methyladenosine (m A) regulators are involved in the progression of various cancers via regulating m A modification. However, potential role and mechanism modification osteosarcoma remains obscure. In this study, WTAP was found to be highly expressed tissue it an independent prognostic factor for overall survival osteosarcoma. Functionally, WTAP, as oncogene, proliferation metastasis vitro vivo. Mechanistically, M dot blot, RNA-seq MeRIP-seq, MeRIP-qRT-PCR luciferase reporter...
The switch between osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays a key role in aging-induced osteoporosis. In this study, miR-19a-3p was obviously downregulated BMSCs from aged humans mice. Overexpressed evidently reduced loss mice promoted BMSCs, while silenced manifestly increased repressed BMSCs. Hoxa5 significantly the contribute to miR-19a-3p-induced osteoblast as direct target gene miR-19a-3p. Furthermore, lncRNA Xist found sponge repress...
Abstract Bruceantinol (BOL) is a quassinoid compound found in the fruits of Brucea javanica. Previous research has highlighted manifold physiological and pharmacological activities BOL. Notably, BOL demonstrated antitumor cytotoxic antibacterial effects, lending support to its potential as promising therapeutic agent for various diseases. Despite being recognized potent inhibitor multiple cancer types, efficacy against osteosarcoma (OS) not been elucidated. In this work, we investigated...
We compared pulmonary function indices and quantitative CT parameters of airway remodeling, air trapping, emphysema in asthmatic patients with COPD asthma-COPD overlap (ACO) explored their relationships airflow limitation.