A5017621482- Advanced Battery Materials and Technologies
- Advancements in Battery Materials
- Supercapacitor Materials and Fabrication
- Spine and Intervertebral Disc Pathology
- Osteoarthritis Treatment and Mechanisms
- Cervical and Thoracic Myelopathy
- Cancer-related molecular mechanisms research
- Spinal Fractures and Fixation Techniques
- Cytokine Signaling Pathways and Interactions
- Advanced Battery Technologies Research
- Forensic Entomology and Diptera Studies
- Nanoparticle-Based Drug Delivery
- Circular RNAs in diseases
- Nanoplatforms for cancer theranostics
- RNA modifications and cancer
- Bone and Joint Diseases
- Extraction and Separation Processes
- Cancer-related gene regulation
- Forensic and Genetic Research
- 3D Printing in Biomedical Research
- Forensic Anthropology and Bioarchaeology Studies
- Extracellular vesicles in disease
- Electrospun Nanofibers in Biomedical Applications
- Erosion and Abrasive Machining
- Thermal Expansion and Ionic Conductivity
Xi'an University of Science and Technology
2024
Third Xiangya Hospital
2018-2024
Central South University
2015-2024
Harbin Institute of Technology
2018-2024
Xiangya Hospital Central South University
2022-2024
FORCE Technology (Norway)
2023
Chinese Academy of Sciences
2023
Hohai University
2021
Shenzhen Institute of Information Technology
2020
Northeastern University
2019
Abstract Li‐rich oxide is a promising candidate for the cathodes of next‐generation lithium‐ion batteries. However, its utilization restricted by cycling instability and inferior rate capability. To tackle these issues, three‐dimensional (3D), hierarchical, cube‐maze‐like assembled from two‐dimensional (2D), thin nanosheets with exposed {010} active planes, are developed facile hydrothermal approach. Benefiting their unique architecture, 3D demonstrate superior reversible capacity (285.3 mAh...
Abstract N 6 -methyladenosine (m A) regulators are involved in the progression of various cancers via regulating m A modification. However, potential role and mechanism modification osteosarcoma remains obscure. In this study, WTAP was found to be highly expressed tissue it an independent prognostic factor for overall survival osteosarcoma. Functionally, WTAP, as oncogene, proliferation metastasis vitro vivo. Mechanistically, M dot blot, RNA-seq MeRIP-seq, MeRIP-qRT-PCR luciferase reporter...
In bone tissue engineering studies, establishing vascular networks plays a crucial role in enhancing graft repair strategies. While most engineered bones rely on host invasion after implantation, this process is often slow. Therefore, exploring highly vascularized strategies may be beneficial to improving the success of repair. This study aimed construct scaffolds with biomimetic using dual-model composite printing promote angiogenic integration and enhance osteogenic First, polycaprolactone...
The switch between osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays a key role in aging-induced osteoporosis. In this study, miR-19a-3p was obviously downregulated BMSCs from aged humans mice. Overexpressed evidently reduced loss mice promoted BMSCs, while silenced manifestly increased repressed BMSCs. Hoxa5 significantly the contribute to miR-19a-3p-induced osteoblast as direct target gene miR-19a-3p. Furthermore, lncRNA Xist found sponge repress...
Lumbar facet joint osteoarthritis (LFJ OA) is regarded as one of the common causes low back pain (LBP). The pathogenesis and underlying mechanism this disease are largely unknown, there still no effective disease-modifying therapy. This study aims to investigate efficacy exosomes derived from bone marrow mesenchymal stem cells (BMSCs) on behavioral signs LBP in LFJ OA mouse model. pathogenetic change cartilage aberrant nerve invasion subchondral a model after treatment with BMSC-exosomes was...
Mesoporous silica nanoparticles (MSNs) carrying gatekeepers that are stimuli-responsive widely investigated for the controlled delivery of drug at target sites. In this study, thioketal (TK) functionalized methoxy poly(ethylene glycol) (mPEG-TK) as ROS-responsive gatekeeper is used to modify MSNs and leads a reactive oxygen species (ROS)-responsive antibacterial drug. Vancomycin (Van) was taken then physically encapsulated into surface amino (N-MSNs). Subsequently, mPEG-TK immobilized. Van...
Three-dimensional (3D) bioprinting is an advanced tissue engineering technique that has received a lot of interest in the past years. We aimed to highlight characteristics articles on 3D bioprinting, especially terms research hotspots and focus. Publications related from 2007 2022 were acquired Web Science Core Collection database. have used VOSviewer, CiteSpace, R-bibliometrix perform various analyses 3,327 published articles. The number annual publications increasing globally, trend...
Abstract Tanshinone I (Tan I) is a widely used diterpene compound derived from the traditional Chinese herb Danshen. Increasing evidence suggests that it exhibits anti‐cancer activity in various human cancers. However, vitro and vivo effects of Tan on osteosarcoma (OS) remain inadequately elucidated, especially those against tumour metastasis. Our results showed significantly inhibited OS cancer cell proliferation, migration invasion induced apoptosis vitro. Moreover, treatment with 10 20...
Iron-based sulfides have been deemed as an appealing anode material for lithium-ion batteries (LIBs) and sodium-ion (SIBs) their high theoretical capacity low cost. However, practical application is limited by drastic volume expansion during cycling low-intrinsic electronic conductivity. In this work, we report a FeS2/Fe7S8-rGO composite synthesized via facile solvothermal method LIB/SIB anode. The exhibits excellent Li-storage of 514 mAh g-1 at 2.0 A after 3000 cycles Na-storage 650 0.2 250...
Chemotherapy is one of the main treatment methods for osteosarcoma. However, conventional chemotherapy lacks targeting properties, and its long-term extensive use will have serious side effects on patients. For this reason, a multifunctional nanodrug system (V-RZCD) osteosarcoma was developed in study. V-RZCD consists two parts: (1) core (ZCD), wherein calcium ions (Ca2+) zoledronic acid (ZA) form metal–organic framework loading doxorubicin (DOX), (2) shell (V-R), vascular endothelial growth...
The heterogeneity of osteoarthritis (OA) significantly limits the effectiveness pharmacological treatments in an unselected patient population. In this context, identification OA subtypes is meaningful for development therapies that target specific types pathogenesis.Expression array profiles 70 and 36 control synovial samples were extracted from GEO database. Unsupervised consensus clustering was performed based on most variable genes to identify subclusters. Next, Joint patients obtained....
Abstract Bruceantinol (BOL) is a quassinoid compound found in the fruits of Brucea javanica. Previous research has highlighted manifold physiological and pharmacological activities BOL. Notably, BOL demonstrated antitumor cytotoxic antibacterial effects, lending support to its potential as promising therapeutic agent for various diseases. Despite being recognized potent inhibitor multiple cancer types, efficacy against osteosarcoma (OS) not been elucidated. In this work, we investigated...