A5025260885- Hidradenitis Suppurativa and Treatments
- Colorectal and Anal Carcinomas
- Anorectal Disease Treatments and Outcomes
- Chemotherapy-related skin toxicity
- Microscopic Colitis
- Dermatology and Skin Diseases
- Cutaneous Melanoma Detection and Management
- Psoriasis: Treatment and Pathogenesis
- Autoimmune and Inflammatory Disorders
- Asthma and respiratory diseases
- Cutaneous lymphoproliferative disorders research
- Medicine and Dermatology Studies History
- Nonmelanoma Skin Cancer Studies
- Infectious Diseases and Mycology
- Genetic and Kidney Cyst Diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Renal cell carcinoma treatment
University Medical Center Groningen
2019-2023
University of Groningen
2019-2023
Massachusetts General Hospital
2017
Harvard University
2017
Erasmus MC
2014-2015
Erasmus University Rotterdam
2014
Abstract Background The effectiveness of available biologics for the treatment hidradenitis suppurativa (HS) is limited. Additional therapeutic options are needed. Objectives To investigate efficacy and mode action guselkumab [an anti-interleukin (IL)-23p19 monoclonal antibody] 200 mg subcutaneously every 4 weeks 16 in patients with HS. Methods An open-label, multicentre, phase IIa trial moderate-to-severe HS was carried out (NCT04061395). pharmacodynamic response skin blood measured after...
Lentigo maligna is a slowly growing melanoma in situ. Current guidelines advise wide local excision with margin of 5 mm as the treatment first choice, which has recurrence rates ranging from 6% to 20%.To determine retrospectively rate lentigo after staged surgical excision.Records all patients treated our method between 2002 and 2011 were retrieved. To identify recurrences we used computer program Sympathy, linked PALGA, nationwide network registry histo- cytopathology Netherlands.We...
Abstract Background Hidradenitis suppurativa (HS) is a chronic debilitating skin disease, frequently located in the groin and anogenital area, leading to substantial impact on quality of life sexual health patients with HS. Skin‐tissue‐sparing excision electrosurgical peeling (STEEP) procedure known low recurrence rates high patient satisfaction retrospective series. However, prospective study investigate any major surgery specific aspects has not yet been performed. Objective To assess...
Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin condition and associated with several comorbidities. Previous studies report variable prevalence rates of HS, depending on the methodology. However, exact remains unknown. To estimate HS in large population‐based cohort Northern Netherlands, to compare patients general population, investigate characteristics identify potential Data were collected through cross‐sectional survey‐based study within Lifelines Cohort Study (n = 167...
Background Biologics are often required for the treatment of hidradenitis suppurativa (HS). However, data on drug survival biologics in daily practice currently lacking. Objectives To assess antitumour necrosis factor a cohort patients with HS and to identify predictors survival. Methods A retrospective multicentre study was performed two academic dermatology centres Netherlands. Adult using between 2008 2020 were included. Drug analysed Kaplan–Meier curves univariate Cox regression...
Psoriasis is a chronic autoimmune disease which affects millions of people worldwide. Not only can psoriasis itself be debilitating and significantly reduce an individual's quality life, but it also risk factor for other systemic disorders, such as metabolic syndrome, cardiovascular disease, malignancy. Tremendous strides were made in the treatment during mid-to-late-20th century, including emergence topical corticosteroids vitamin D analogs, methotrexate, retinoids, phototherapy. However,...
To the Editor: Matusiak et al1Matusiak Ł. Bieniek A. Szepietowski J.C. Hidradenitis suppurativa markedly decreases quality of life and professional activity.J Am Acad Dermatol. 2010; 62: 706-708Abstract Full Text PDF PubMed Scopus (142) Google Scholar showed that hidradenitis (HS) caused absenteeism in 58.1% patients. However, work impairment due to HS is not limited but could also lead presenteeism (reduced productivity while at work) at-work loss (absenteeism plus presenteeism). Knowledge...
Cohort studies on the use of retinoids for hidradenitis suppurativa (HS) have yielded contradicting results. As clinical presentation HS is heterogeneous, with different predilection sites and hallmark features, it can be hypothesized that phenotypes are associated effectiveness specific retinoid treatments.The aim this study was to evaluate drug survival oral in treatment establish predictors longer duration.A retrospective, dual-center conducted Netherlands adult patients treated between...
Abstract Hidradenitis Suppurativa (HS) is a chronic debilitating skin condition that impairs the productivity and quality of patients` lives. HS has recently drawn lots attention among scholars to further expand their knowledge but it still loads with uncertainties gaps be explored. This publication addresses these uncertainties, provides road‐map for researchers, clinicians from different disciplines future studies about HS. proceeding report first Symposium on Advances (SHSA), reviews...
SFH who presented to our outpatient department between 2005 and 2019 underwent cervical cerebral MRI (cMRI) with MRA for the evaluation of CVA anomalies.Infantile haemangioma following characteristics were considered segmental: (i) positive criteria: long plaque-type covering (part of) a cutaneous territory (ii) negative round or oval form, pedunculation.CVA anomalies stratified according Metry et al. 7 Hess 4 as low risk (dysgenetic persistence embryonal vessels, anomalous course and/or...
Background The exact influence of the Body Mass Index (BMI) on outcome laparoscopic donor nephrectomy (LDN) is still under debate. We hypothesized that other parameters, such as fat mass, may have a stronger correlation with perioperative complications and short-term results LDN. Methods A retrospective database search pre-operative imaging review were conducted in cohort live kidney donors who underwent LDN between 2004 2013 our centre. Of 620 donors, compatible was available. volumetric...
Psoriasis ist eine chronische Autoimmunerkrankung, von der weltweit Millionen Menschen betroffen sind. Die Erkrankung nicht nur für sich selbst genommen sehr belastend und kann die Lebensqualität verringern, sondern sie stellt auch einen Risikofaktor weitere systemische Erkrankungen dar, z.B. metabolisches Syndrom, kardiovaskuläre maligne Erkrankungen. In Behandlung wurden im mittleren bis späten 20. Jahrhundert bahnbrechende Fortschritte erzielt, unter anderem durch Entwicklung topischen...