A5110685864- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Advanced Radiotherapy Techniques
- Inhalation and Respiratory Drug Delivery
- Respiratory and Cough-Related Research
- Regulation of Appetite and Obesity
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Antifungal resistance and susceptibility
- Nail Diseases and Treatments
- Prostate Cancer Diagnosis and Treatment
- Cutaneous Melanoma Detection and Management
- Mast cells and histamine
- Nonmelanoma Skin Cancer Studies
- Contact Dermatitis and Allergies
- Indoor Air Quality and Microbial Exposure
- Prostate Cancer Treatment and Research
- Occupational exposure and asthma
- Biochemical Analysis and Sensing Techniques
- Fungal Plant Pathogen Control
- Brain Metastases and Treatment
- Pharmaceutical studies and practices
- Food Allergy and Anaphylaxis Research
- Mycotoxins in Agriculture and Food
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
University of Twente
2025
Erasmus MC Cancer Institute
2020-2024
Klinikum Osnabrück
2023
Erasmus MC
2012-2023
Erasmus University Rotterdam
2020-2023
New Generation University College
2017
Seoul National University
2017
University Medical Center Groningen
1964-2015
California State University, Stanislaus
2009
Molecular Research Institute
2003-2005
Summary This study was undertaken to confirm the high incidence of ‘late’ bronchial reaction after house dust inhalation and assess whether symptoms signs these reactions were comparable with clinical features classic Type III (Gell Coombs) allergic in lung as shown by extrinsic alveolitis. Although time sequence this late is agreement Ml (Arthus phenomenon), other alveolitis are absent. There no crepitations on physical examination, fever, leucocytes, decrease PaO 2 , abnormal radiological...
We evaluated factors that might influence the course of lung function after 2 to 21 yr follow-up in 81 nonallergic patients with chronic air-flow obstruction (CAO) and considerable impairment (initial forced expiratory volume one second as a percentage inspiratory slow vital capacity (FEV1 % VC) ranging from 40 55% increasing less than 15% administration anticholinergic bronchodilator thiazinamium). A more favorable rate change FEV1 was associated pack-years smoking, nonspecific...
A study was undertaken to see whether the principal airborne fungi in North‐East Netherlands were also found be most reactive skin testing. Atmospheric samples taken weekly with Andersen sampler, from April 1981, up and including, June 1983, At same time tests of 833 patients referred outpatient Departments Pulmonology Allergology, because recurrent bronchial obstructive complaints a suspected allergy, studied for strongly positive reactivity fungi. 4.6% reacted wheal 10 mm diameter or more...
Lentigo maligna is a slowly growing melanoma in situ. Current guidelines advise wide local excision with margin of 5 mm as the treatment first choice, which has recurrence rates ranging from 6% to 20%.To determine retrospectively rate lentigo after staged surgical excision.Records all patients treated our method between 2002 and 2011 were retrieved. To identify recurrences we used computer program Sympathy, linked PALGA, nationwide network registry histo- cytopathology Netherlands.We...
<title>Abstract</title> Background Post-hepatectomy liver failure (PHLF) is a serious complication following hepatic resection and associated with high mortality rate. The risk of PHLF can be estimated pre-resection by assessing the function future remnant (FLR) using hepatobiliary scintigraphy (HBS). Inaccurate estimation have profound consequences, including an incorrect decision whether or not to proceed resection. Therefore, it essential determine reproducibility preoperative assessment...
Three different stages were found during growth of <i>Aspergillus fumigatus</i> as characterized by the changes in pH medium: (1) An acidic phase (phase I); (2) a second II) which rises till values around = 8.5; (3) third III) remains constant or drops slightly. During I fast appearance certain antigenic components was that is ascribed to an active process excretion. Additional appeared culture medium after lysis microorganisms (phases II and III). Lysis are dependent on glucose...
The degree of airway hyperresponsiveness in allergic asthmatic patients may be influenced by changes environmental exposure to inhalant allergens.This study investigates the relationship between seasonal house dust mite (HDM) allergens and non-specific with multiple sensitizations inhaled allergens.In 43 sensitized several allergens, lung function (FEV1), (PC20 histamine), serum total IgE, specific IgE number peripheral blood eosinophils were measured during autumn 1990 (September-November)...
Germline and tumour genetic testing in prostate cancer (PCa) is becoming more broadly accepted, but indications clinical consequences for carriers each disease stage are not yet well defined. To determine the consensus of a Dutch multidisciplinary expert panel on indication application germline PCa. The consisted 39 specialists involved PCa management. We used modified Delphi method consisting two voting rounds virtual meeting. Consensus was reached if ≥75% panellists chose same option....
During cultivation of Aspergillus fumigatus a rapid liberation IgE-binding components was found reaching maximum values during the logarithmic phase growth (phase I). After fall in titers II, appearance additional noted period lysis microorganism III). These latter allergenic are different from I components, as shown by crossed-inhibition studies. The number precipitating antigenic not related with corresponding and showed an increase all phases growth. changes both IgE- IgG-binding...
After radiation therapy for painful bone metastases, up to 44% of patients report a pain flare (PF). Our study compared 2 dose schedules dexamethasone versus placebo prevent PF.This double-blind, randomized, placebo-controlled trial allocated with metastases from solid tumors randomly receive 8 mg before followed by 3 daily doses (group A), B), or 4 C). Patients reported worst scores, medication side effects, and opioid intake treatment thereafter 14 days on day 28. PF was defined as at...
Four allergologically important fungi, viz. Aspergillus Fumigatus, Penicillium notatum, Alternaria alternata, and Cladosporium herbarum were cultured in a liquid synthetic medium, with or without addition of 0.1 % yeast extract (YE). After 10 28 days cultivation, immunochemical properties the fungal extracts, characterised by precipitation pattern IgG– IgE‐binding capacity, studied. In pure medium no large differences observed number precipitates, as measured DID, among four antigenic...
Individual antigenic components of <i>Aspergillus fumigatus </i>were identified by crossed immunoelectrophoresis (CIE) using pooled rabbit hyperimmune antiserum. Patients’ sera with enhanced precipitins against <i>A. </i>showed antibodies identical in CIE. Identification the intermediate gel technique showed high concentrations a small group components. No differences were found indiviual involved precipitation reactions between groups and normal IgE levels fumigatus....