A5034621238- Bone fractures and treatments
- Bone health and osteoporosis research
- Cardiac, Anesthesia and Surgical Outcomes
- Bone and Joint Diseases
- Spinal Fractures and Fixation Techniques
- Anesthesia and Pain Management
- Vascular Malformations Diagnosis and Treatment
- Bone health and treatments
- Pelvic and Acetabular Injuries
- Bone Metabolism and Diseases
- Osteoarthritis Treatment and Mechanisms
- Cervical and Thoracic Myelopathy
- Spine and Intervertebral Disc Pathology
- Trauma and Emergency Care Studies
- Radiology practices and education
Duke Medical Center
2021
Vanderbilt University Medical Center
2018-2021
Vanderbilt University
2018-2019
Bone fractures create five problems that must be resolved: bleeding, risk of infection, hypoxia, disproportionate strain, and inability to bear weight. There have been enormous advancements in our understanding the molecular mechanisms resolve these after fractures, best clinical practices repairing fractures. We put forth a modern, comprehensive model fracture repair synthesizes literature on biology biomechanics address primary This updated is framework for both management future studies...
Background context Pseudarthrosis following spinal fusion remains problematic despite modern surgical and grafting techniques. In fusion, new bone forms via intramembranous endochondral ossification, with ossification occurring in the hypoxic zones of bed. During development fracture healing, key cellular mediator is hypertrophic chondrocyte given its ability to function hypoxia induce neovascularization ossification. We therefore hypothesize that chondrocytes may be an effective graft...
Introduction: Spinal arteriovenous malformations (AVMs) are rare neurologic lesions composed of abnormal blood vessels. The clinical symptoms associated with this pathology extremely variable and may range from diffuse pain to progressive myelopathy subsequent muscle weakness. To inhibit potential disease progression neurological deterioration, early recognition these important. In report we present the case an adolescent male athlete cervical secondary a vertebral artery AVM. We discuss...