A5058591494- Health and Lifestyle Studies
- Diabetes Management and Research
- Obesity, Physical Activity, Diet
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Autophagy in Disease and Therapy
- Birth, Development, and Health
- Diabetes Treatment and Management
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Pharmaceutical studies and practices
- Gestational Diabetes Research and Management
- Diet and metabolism studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes Management and Education
- Adipose Tissue and Metabolism
- Health Systems, Economic Evaluations, Quality of Life
- Pregnancy and preeclampsia studies
- Adipokines, Inflammation, and Metabolic Diseases
- Endoplasmic Reticulum Stress and Disease
- High Altitude and Hypoxia
- Pharmacology and Obesity Treatment
- Inflammatory mediators and NSAID effects
- Vitamin D Research Studies
- Acute Ischemic Stroke Management
- Pharmaceutical Practices and Patient Outcomes
Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno
2013-2025
University of Buenos Aires
2015-2024
Consejo Nacional de Investigaciones Científicas y Técnicas
2007-2024
Argentine Water and Sanitation (Argentina)
2024
Austral University
2010-2023
Favaloro University
2012-2023
MSD (Mexico)
2023
Hospital Barros Luco-Trudeau
2023
Merck & Co., Inc., Rahway, NJ, USA (United States)
2015-2021
Sociedad de Biología de Chile
1970-2021
Abstract. Objective. The major function of the circadian system is internal cycling physiological and metabolic events. present study sought to explore effect rotating shift work schedule on leucocyte count its relationship with risk factors syndrome (MS). Design participants. From a population‐based design, 1351 men self‐reported European ancestry were included in cross‐sectional study: 877 day workers compared 474 workers. Medical history, health examination including anthropometric...
Autophagy has recently elicited significant attention as a mechanism that either protects or promotes cell death, although different autophagy pathways, and the cellular context in which they occur, remain to be elucidated. We report thorough biochemical characterization of novel selective works protective response. This new is activated pancreatic acinar cells during pancreatitis-induced vesicular transport alteration sequester degrade potentially deleterious zymogen granules. have coined...
We explored peroxisome proliferator‐activated receptor‐γ co‐activator 1α gene (PPARGC1A), (PPARG), and transcription factor A mitochondrial ( Tfam ) promoter DNA methylation in newborns between both extremes of abnormal fetal growth: Small (SGA) large for gestational age (LGA) relation to the mother's characteristics. further sought association rs9930506 variant at FTO patterns aforementioned genes, offspring's birth weight. In a cross‐sectional study, 88 healthy pregnant women their babies...
Introduction and Objective Diabetes is characterized by chronic inflammation, endothelial dysfunction, increased risk of infections early cardiovascular disease. By releasing neutrophil extracellular traps (NETs), neutrophils kill bacteria exert pro-inflammatory pro-thrombotic activities. Increased NETosis has been found in cross-sectional studies including treated type 2 diabetes mellitus (T2DM) patients. In this study, we determined whether the ability to form NETs differs diabetic...
Background — Despite the use of heparin, aspirin, and other antiplatelet agents, acute coronary syndrome patients without ST-segment elevation remain at risk cardiovascular thrombotic events. Given role inflammation in pathogenesis arterial thrombosis, we tested hypothesis that combination meloxicam, a preferential COX-2 inhibitor, heparin aspirin would be superior to alone. Methods Results In an open-label, randomized, prospective, single-blind pilot study, with syndromes were randomized...
The present study investigated the role of N , {′ }-dimethylbiguanide metformin (50 mg/100 g body weight in 0.05 ml water, given orally with a canulla) prevention endocrine and immune disorders provoked by hyperandrogenization dehydroepiandrosterone (DHEA) prepuberal BALB/c mice. treatment DHEA (6 0.1 oil) for 20 consecutive days, recreates mouse model that resembles some aspects human polycystic ovary syndrome (PCOS). did not modify either mass index (BMI) or blood glucose levels, but...
Abstract Obesity and hypertension are increasing medical problems in adolescents. Serotonin transporter (5‐HTT) is involved mood eating disturbances. Encoded by the gene SLC6A4 , promoter shows functional insertion/deletion alleles: long (L) short (S). Because individuals who carriers for version known to be at risk higher levels of anxiety, we hypothesized that this variant may associated with overweight. Data blood samples were collected from 172 adolescents out a cross‐sectional,...
The aim of this study was to investigate whether mitochondrial DNA (mtDNA) content is associated with insulin resistance (IR) in a sample adolescents features metabolic syndrome. We further studied the link between polymorphisms three genes involved biogenesis and presence deleted mtDNA content. Data blood samples were collected from 175 out cross-sectional, population-based 934 high school students. On basis median value homeostasis model assessment IR (HOMA-IR) whole (2.2), population...
Abstract Background and purpose Despite enormous advances in identifying genetic variants responsible for many neurological diseases, access to testing may be limited clinical practice. The objective of this study was assess worldwide tests movement disorders factors impacting their utilization. Methods Rare Movement Disorders Study Group the International Parkinson Disorder Society designed an online survey electronically mailed all 7815 members. Results Survey data completed by 1269...