Yaochen Xie

ORCID: 0000-0002-3779-8971
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About
Contact & Profiles
Research Areas
  • Pharmacology and Obesity Treatment
  • Diabetes Treatment and Management
  • Medicinal Plants and Bioactive Compounds
  • Cancer-related Molecular Pathways
  • RNA modifications and cancer
  • Renal and related cancers
  • Lanthanide and Transition Metal Complexes
  • Antimicrobial Peptides and Activities
  • Luminescence and Fluorescent Materials
  • Cancer, Lipids, and Metabolism
  • Metabolomics and Mass Spectrometry Studies
  • Immune cells in cancer
  • Glycosylation and Glycoproteins Research
  • Immune Response and Inflammation
  • Alcohol Consumption and Health Effects
  • Drug-Induced Hepatotoxicity and Protection
  • Pharmacological Effects of Natural Compounds
  • Polydiacetylene-based materials and applications
  • Traditional Chinese Medicine Studies
  • Metal-Organic Frameworks: Synthesis and Applications
  • Sulfur Compounds in Biology
  • Liver Disease and Transplantation
  • Advanced Biosensing Techniques and Applications
  • Peroxisome Proliferator-Activated Receptors
  • Diabetes Management and Research

Hainan University
2024-2025

ZheJiang Institute For Food and Drug Control
2022-2024

Zhejiang University
2022-2024

Nanjing University of Chinese Medicine
2019-2020

Salmonella infections can lead to intestinal inflammation and metabolic disorders in birds. However, whether arachidonic acid (ARA) metabolism is involved -induced remains unclear. This experiment investigated the changes cecal flora ARA Hainan Wenchang chickens infected with S. Typhimurium using 16s rDNA sequencing targeted metabolomics. The results showed that levels of metabolites were increased cecum tissue after infection , including prostaglandin E2 (PGE 2 ), F2α (PGF 2α lipoxin A4...

10.3389/fmicb.2025.1514115 article EN cc-by Frontiers in Microbiology 2025-01-24

Abstract Background In recent years, copper complexes have gradually become the focus of potential anticancer drugs due to their available redox properties and low toxicity. this study, a novel mitochondrion-targeting (II) complex, [Cu (ttpy-tpp)Br 2 ] Br (simplified as CTB), is first synthesized by our group. CTB with tri-phenyl-phosphine (TPP), targeting lipophilic group, can cross cytoplasmic mitochondrial membranes tumor cells. The present study aims investigate how affects functions...

10.1186/s12964-019-0468-6 article EN cc-by Cell Communication and Signaling 2019-11-19

Salmonella infections can lead to intestinal inflammation and metabolic disorders in birds. However, whether ARA metabolism is involved Salmonella-induced remains unclear. This experiment investigated the changes cecal flora arachidonic acid (ARA) Hainan Wenchang chickens infected with S. Typhimurium using 16s rDNA sequencing targeted metabolomics. The results showed that levels of metabolites were increased cecum tissue after infection Typhimurium, including prostaglandin E2, F2α, lipoxin...

10.20944/preprints202404.1170.v1 preprint EN 2024-04-17

Herein we synthesize a DNA-sensitized Tb-MOF conjugate (DNA-Tb-MOF) as time-resolved luminescent probe to sensitively and selectively assay SO<sub>2</sub> their derivatives (<italic>i.e.</italic>, HSO<sub>3</sub><sup>−</sup>) through photoluminescence off–on effect.

10.1039/d0an00861c article EN The Analyst 2020-01-01

The treatment on patients with T2DM who suffered from defective in insulin secretion and inability of tissues responding to properly have been studied for decades. Currently, incretins-based hypoglycemic agents become a focus treating this kind drugs could be classified as GLP-1 receptor agonists which mimic the function DPP-4 antagonists avoid being degraded. Both them focused polypeptide. Since are widely used, physiological disposition is great significance discovering more effective...

10.22541/au.170670903.33408087/v1 preprint EN Authorea (Authorea) 2024-01-31

Abstract Huanglian Jiedu Decoction (HJD) is a well-known Traditional Chinese Medicine formula that has been used for liver protection in thousands of years. However, the therapeutic effects and mechanisms HJD treating drug-induced injury (DILI) remain unknown. In this study, total 26 genes related to both DILI were identified, which are corresponding 41 potential active compounds HJD. KEGG analysis revealed Tryptophan metabolism pathway particularly important. The overlapped from GO...

10.1186/s12906-024-04517-y article EN cc-by BMC Complementary Medicine and Therapies 2024-06-07
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