A5013076235- Glioma Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- MRI in cancer diagnosis
- Brain Metastases and Treatment
- Advanced MRI Techniques and Applications
- Lung Cancer Research Studies
- Alcoholism and Thiamine Deficiency
- Amino Acid Enzymes and Metabolism
- Neurological and metabolic disorders
- Multiple Sclerosis Research Studies
- Neurological Complications and Syndromes
- Ultrasound and Hyperthermia Applications
- CNS Lymphoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Infectious Encephalopathies and Encephalitis
- Circular RNAs in diseases
- Radiomics and Machine Learning in Medical Imaging
- Advanced Neuroimaging Techniques and Applications
- Polyomavirus and related diseases
Ministry of Health of the Russian Federation
2019-2023
Russian Cancer Research Center NN Blokhin
2018-2019
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, primarily affecting individuals with severe immunosuppression. Its subacute onset, nonspecific clinical manifestations, and MRI findings complicate accurate timely diagnosis. This review provides brief overview etiology fundamental pathogenesis disease, demonstrating through case importance multimodal approach potential challenges in differential diagnosis PML.
Wernicke encephalopathy (WE)is a rareneurologicaldisorderinducedby vitaminB1 deficiency(thiamine), which is associated with high risks of Korsakoff psychosis and death in case untimely initiation ofspecific therapy. In addition to clinical laboratory data, magnetic resonance imaging (MRI) the brain, has fairly specificity, plays an important role detecting this pathology. However, degree awareness ofWE by radiologists necessary for correct interpretation ofMRI data. This publication presents...
The study objective is to assess the possibilities of magnetic resonance imaging (MRI) in SWI (susceptibility weighted imaging) differential diagnosis glial brain tumors and primary lymphomas. Materials methods. Fifty-four patients with were studied (men – 27 (50 %), women %)). Average age 57.9 years. Histological examination surgical material revealed nature 41 (26 them glioblastoma, anaplastic astrocytomas 15), lymphomas 13 patients. Brain MRI was performed using tomographs a field 3 1.5...
Background: Metastatic brain lesions lead to the most unfavorable prognosis for course of an oncological disease. Most often, metastases arise from primary tumors such as lung cancer, breast and melanoma. Of particular interest are groups secondary intracranial without identified focus. Methods non-invasive differential diagnosis based on a possible histological affiliation, including diffusion-kurtosis magnetic resonance imaging, can improve diagnostic search tumor. Aim: The aim this study...
In recent years there has been intensive development and clinical implementation of new techniques noninvasive radiology diagnostics that measure characteristics blood flow in tumors, which is one the most important mechanisms tumor growth contribute to ability tumors respond ongoing systemic therapy. Awareness clinicians about features perfusion characteristics, this context brain an condition for optimizing results use drugs aimed at suppression neoangiogenesis. Established tissue CT MRI...
The aim : to examine the possibility of using dynamic contrast enhanced magnetic resonance imaging (DCE MRI) in clarifying diagnosis glial brain tumors and differentiation between them on basis malignancy degree. In this regard, authors evaluated effectiveness perfusion parameters (Ktrans, Kep, Ve iAUC). Materials methods. study included examination 54 patients with an established presence tumors. Glioma Grade I–II diagnosed 13 (24.1%) glioma III–IV 41 (75.9%) cases. Morphological...
Abstract BACKGROUND Brain metastases (BM) affect 8%-10% of all cancer patients and 40% with metastatic cancer. The majority BM originate from lung (40%-50%), breast (15%-25%), melanoma (5%-20%). Total incidence proportions percentage (IP %) brain was reported as 9.6% for primary sites combined, highest (19.9%). is believed to be increasing, likely resulting longer patient survival due more effective systemic therapies the increased use neuroimaging in neurologically asymptomatic patients....
Modern advances in oncology can achieve significantly better results terms of life expectancy patients with metastatic brain disease. The combination surgery, systemic therapy, whole irradiation and local methods radiation therapy lead to good indicators for controlling the manifestations disease brain. Of course, intensification treatment increases risk iatrogenic complications. use aggressive stereotactic radiotherapy regimens leads not only high control irradiated metastases, but also...
Primary lymphomas of the central nervous system (PCLCS) are relatively rare tumors, usually having a multifocal manifestation in brain and rapid progression. It is not always possible to make correct diagnosis for MRI, since similar radiological manifestations (markers) this disease, when using routine protocols, MRI can occur, example, malignant gliomas. This article presents clinical case refinement — PLCNS sequence (SWI), which was confirmed by data histological examination surgical material.