A5036130199- Lipid Membrane Structure and Behavior
- Erythrocyte Function and Pathophysiology
- Surfactants and Colloidal Systems
- Spectroscopy and Quantum Chemical Studies
- Ionic liquids properties and applications
- Chalcogenide Semiconductor Thin Films
- Protein Structure and Dynamics
- Electrochemical Analysis and Applications
- Electronic and Structural Properties of Oxides
- Polymer Surface Interaction Studies
- Quantum Dots Synthesis And Properties
- Perovskite Materials and Applications
- Graphene and Nanomaterials Applications
- Pickering emulsions and particle stabilization
- Hemoglobin structure and function
- Iron oxide chemistry and applications
- ZnO doping and properties
- Porphyrin and Phthalocyanine Chemistry
- Antimicrobial Peptides and Activities
- Supramolecular Self-Assembly in Materials
- Blood properties and coagulation
- Geophysical and Geoelectrical Methods
- Advanced Photocatalysis Techniques
- Semiconductor materials and devices
- RNA Interference and Gene Delivery
Fachhochschule Kiel
2021-2025
Kiel University
2019-2025
Saha Institute of Nuclear Physics
2016-2024
Homi Bhabha National Institute
2018-2024
Indian Institute of Technology Dhanbad
2024
Osaka University
2019
Murphy Oil Corporation (United States)
2019
Ionic liquids (ILs) are important for their antimicrobial activity and found to be toxic some microorganisms. To shed light on the mechanism of activities, interaction an imidazolium-based IL 1-butyl-3-methylimidazolium tetrfluoroborate ([BMIM][BF4]) with E. coli bacteria cell-membrane-mimicking lipid mono- bilayers has been studied. The survival corresponding growth inhibition observed functions concentration IL. alters pressure–area isotherm monolayer formed at air–water interface by...
The emerging class of hybrid organic-inorganic perovskites (HOIPs) has exhibited fascinating properties for a wide range technological applications. With halide ions, HOIPs have provided novel optoelectronic devices including efficient solar cells and with pseudohalide anions-like formate (HCOO-), enigmatic electromagnetic been obtained in HOIPs. Large-scale synthesis such 2D HOIP films is immense importance the advancement its application as materials. We shown using in-situ X-ray...
Xanthan gum is a biopolymer used in wide range of products the food and cosmetic industries. As ionic liquids (ILs) have emerged as antimicrobial molecules, they can be preservatives for this polymer. Hence, it important to understand interaction with gum. In investigation, polymer self-assembly at air–water interface has been studied presence floating interface. From surface pressure–area isotherm, shown that electrostatic drives interface, resulting viscoelastic film. In-plane dilation...
Lateral and out-of-plane organization of cholesterol its effect on regulating the physicochemical properties zwitterionic phospholipid model membranes have been investigated by a pressure–area isotherm study from Langmuir monolayer, atomic force microscopy (AFM), X-ray reflectivity (XRR) measurements supported binary monolayer films. The systematic studies phospholipids subsequent extraction excess Gibbs free energy (ΔGexc) revealed mechanism interaction molecular cooperativeness for...
Fundamental insights into the interplay and self-assembly of nanoparticles surface-active agents at liquid–liquid interface play a pivotal role in understanding ubiquitous colloidal systems present our natural surroundings, including foods aquatic life, industry for emulsion stabilization, drug delivery, or enhanced oil recovery. Moreover, well-controlled model mixed interfacial adsorption surfactants allow unprecedented nonideal contaminated particle-stabilized emulsions. Here, we...
Luminescent materials possessing both the mechanoluminescence (MCL) and electroluminescence (EL) properties are quest for sensing optoelectronic applications. We report on synthesis of a new tailor-made luminogen, 1,2-bis(4-(1-([1,1′-biphenyl]-4-yl)-2,2-diphenylvinyl)phenyl)-1,2-diphenylethene (TPE 5), using Suzuki coupling reaction with high yield. An aggregation-induced emission (AIE) active complex TPE 5 forms supramolecular spherical aggregates at air–water interface Langmuir trough. As...
Abstract Following the reaction of biological membranes to external stimuli reveals fundamental insights into cellular function. Here, self-assembled lipid monolayers act as model containing photoswitchable azobenzene glycolipids for investigating structural response during isomerization by combining Langmuir isotherms with X-ray scattering. Controlled in-situ trans/cis photoswitching N = double bond alters DPPC monolayer structure, causing reproducible changes in surface pressure and layer...
Abstract 2D organic–inorganic hybrid lead halide perovskite films are fascinating optoelectronic materials for white‐light emission and lasing applications. Here, it is demonstrated that nano‐meter‐thick of perovskites can be formed at room temperature using Langmuir–Schaefer (LS) deposition technique. In situ X‐ray measurements reveal a self‐assembly process the formation air–water interface. This requires presence stearic acid monolayer on water subphase having solution lead‐perovskite in...
We report intrinsic memory effect in magnetization and dielectricity for the spin-chain compound ${\mathrm{Sm}}_{2}{\mathrm{BaNiO}}_{5}$, pointing cooperative glassy response below $\ensuremath{\sim}8\phantom{\rule{0.16em}{0ex}}\mathrm{K}$. Signature of anomaly around 8 K is verified by magnetization, heat capacity, dielectric permittivity, magnetostriction, structural parameters as obtained from synchrotron diffraction studies. Intriguingly, observed well magnetic ferroelectric ordering...
Drug design and targeted delivery in cells serve as a flourishing area not only for scientific inquiry, owing to numerous clinical applications, but also understanding cell interaction with exogenous materials. The membrane localization of heme its analog hemin, one the most biologically relevant planar organic molecule, is very important understand molecular mechanism intercalation adsorption this cytotoxic molecule after dissociation from proteins such hemoglobin. Herein, we investigate...
The graphene family, especially oxide (GO), has captured increasing prospects in the biomedical field due to its excellent physicochemical properties. Understanding health and environmental impact of GO is great importance for guiding future applications. Although their interactions with living organisms are omnipresent, exact molecular mechanism yet be established. cellular membrane first barrier a foreign molecule interact before entering into cell. In present study, model system...
Liquid-liquid interfaces offer intriguing possibilities for nanomaterials growth. Here, fundamental interface-related mechanisms that control the growth behavior in these systems are studied Pb halide formation at interface between NaX + PbX2 (X = F, Cl, Br) and liquid Hg electrodes using situ X-ray scattering complementary electrochemical microscopy measurements. These studies reveal a decisive role of species nucleation compounds. In Cl- Br-containing solution, deposition starts by rapid...
Room-temperature electrodeposition of Ge crystallites was investigated by the electrochemical liquid–liquid–solid (ec-LLS) process using a family Hg1–xInx alloys. The objective to determine whether different liquid metal alloys with nominally same bulk solubility toward but potentially surface character would yield any differences in resultant crystallites. Variation In fraction these control variable. following details were ascertained from cumulative data. First, accordance thermodynamic...
An effort aimed at replacing the conventional water column by a relative humidity (RH) environment for structural investigation of soft polymer cushion-supported model phospholipid membrane has been reported. RH-responsive well-hydrated cushion layer capable approximately 2-fold swellability under RH 96% employed fabrication. To validate proposed method, supported lipid bilayers (SLBs) phosphocholine and phosphoethanolamine were deposited structurally characterized molecular level X-ray...
Monosialoganglioside (GM1), a ubiquitous component of lipid rafts, and hemin, an integral part heme proteins such as hemoglobin, are essential to the cell membranes brain neurons erythrocyte red blood cells for regulating cellular communication oxygen transport. Protoporphyrin IX (PPIX) its derivative on contrary, show significant cytotoxic effects when in excess causing hematological diseases, thalassemia, anemia, malaria, neurodegeneration. However, in-depth molecular etiology their...
Understanding and controlling the structure function of liquid interfaces is a constant challenge in biology, nanoscience nanotechnology, with applications ranging from molecular electronics to controlled drug release. X-ray reflectivity grazing incidence diffraction provide invaluable probes for studying atomic scale at liquid-air interfaces. The new time-resolved laser system LISA diffractometer situated beamline P08 PETRA III synchrotron radiation source Hamburg provides pump probe....
The functionality and efficiency of proteins within a biological membrane are highly dependent on both the lipid composition physiochemical properties solution. Lipid mesophases directly influenced by changes in temperature, pH, water content or due to individual single lipids such as photoswitchability. In this work, we were able induce light- temperature-driven mesophase transitions model system containing mixture 1,2-dipalmitoyl-phosphatidylcholine phospholipids azobenzene amphiphiles. We...