A5036013889- Sperm and Testicular Function
- Reproductive Health and Technologies
- Hormonal and reproductive studies
- Sexual function and dysfunction studies
- Male Reproductive Health Studies
- Reproductive Biology and Fertility
- Prostate Cancer Diagnosis and Treatment
- Testicular diseases and treatments
- Sexual Differentiation and Disorders
- Urinary Bladder and Prostate Research
- Genital Health and Disease
- Urologic and reproductive health conditions
- Ovarian function and disorders
- Prostate Cancer Treatment and Research
- Renal cell carcinoma treatment
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Anesthesia and Pain Management
- Renal and related cancers
- Bladder and Urothelial Cancer Treatments
- Nonmelanoma Skin Cancer Studies
- Cancer and Skin Lesions
- Inflammatory Biomarkers in Disease Prognosis
- Vascular Malformations and Hemangiomas
- Urological Disorders and Treatments
- Eating Disorders and Behaviors
Kaiser Permanente Oakland Medical Center
2014-2020
Kaiser Permanente
2015-2019
Cornell University
2010-2018
Howard Hughes Medical Institute
2018
Emory University
2006-2014
Morehouse School of Medicine
2014
Population Council
2010-2013
Foundation for Reproductive Medicine
2011
New York Hospital Queens
2010-2011
NewYork–Presbyterian Hospital
2010-2011
Purpose Advances in chemotherapy have led to greater longevity and paternity may be an important consideration for postchemotherapy survivors of childhood cancers. While traditionally considered sterile, men who are azoospermic after can treated with microdissection testicular sperm extraction (TESE) intracytoplasmic injection (ICSI). Patients Methods Oncologic data, pretreatment hormone profiles, histology, outcomes TESE-ICSI were reviewed. ICSI was performed a programmed vitro...
Maintenance of adult tissues depends on stem cell self-renewal in local niches. Spermatogonial cells (SSC) are germline necessary for spermatogenesis and fertility. We show that testicular endothelial (TECs) part the SSC niche producing glial line-derived neurotrophic factor (GDNF) other factors to support human mouse SSCs long-term culture. demonstrate FGF-2 binding FGFR1 TECs activates calcineurin pathway produce GDNF. Comparison TEC secretome lung liver identified 5 sufficient maintenance...
It is generally accepted that men with clinically palpable varicocele are at high risk for a progressive decrease in fertility and testosterone levels time. Varicocelectomy thought to improve testicular function or least halt the accelerated associated varicocele. Substantial controversy exists as whether varicocelectomy effective older men, possibly due irreversible damage limited potential recovery from induced damage.We retrospectively reviewed records of who underwent microsurgical...
European Urological Association guidelines recommend potentially curative inguinal lymphadenectomy for certain cases of penile cancer such as grade 3 and pT2-4 lesions, among others. Anecdotally, the authors have noticed that few patients undergo lymphadenectomy. Therefore, they assessed frequency impact dissection extent on survival using Surveillance, Epidemiology, End Results (SEER) database.The queried 17 SEER registries from 1988 through 2005 without distant metastases. Univariate...
Study Type – Outcomes (cohort) Level of Evidence 2b What's known on the subject? and What does study add? Modern surgical techniques have allowed preservation fertility in most patients after post‐chemotherapy retroperitoneal lymph node dissection (PC‐RPLND), but some still infertility surgery. We reviewed our experience treating 26 men PC‐RPLND. Using a structured clinical pathway we obtained sperm 81% for use assisted reproduction. OBJECTIVE To evaluate effectiveness retrieval outcomes...
In the prostate specific antigen era most cancer presents at an early stage. However, a significant number of patients have advanced disease, including those with stage IV disease. Assignment to may occur by different modes, namely as T4N0M0 vs N1 M1 We hypothesize that clinical T4 disease better outcomes than or disease.A total 17 SEER registries were queried from 1995 through 2003. Multivariate and univariate analyses examined overall survival across subcategories while controlling for...
After undergoing vasectomy up to 6% of men will elect undergo reversal. For these paternity can be achieved with reversal or surgical sperm retrieval coupled assisted reproduction. Nevertheless, it remains difficult for surgeons accurately counsel on the chance patency after reversal.A retrospective review was conducted 548 patients who underwent microsurgical Surgery considered successful if concentration 100,000 more per ml, total count ejaculate, motile were present and there no evidence...
Introduction: Laparoscopic radical nephrectomy has quickly evolved as an oncologic standard of care. The "Simple" implies easier procedure than perhaps its counterpart and one that budding laparoscopists may approach with more confidence. Though, strict indications for simple are few, these cases tend to have infectious or inflammatory pathology sometimes making the difficult counterpart. Methods: A retrospective review our experience laparoscopic (LSN) over a 7-year period was performed....
We originally discovered TERE1 as a potential tumor suppressor protein based upon reduced expression in bladder and prostate cancer specimens growth inhibition of cell lines/xenografts ectopic expression. Analysis (aka UBIAD1) has shown it is prenyltransferase enzyme the natural bio-synthetic pathways for both vitamin K-2 COQ10 production exhibits multiple subcellular localizations including mitochondria, endoplasmic reticulum, golgi. Vitamin involved mitochondrial electron transport, SXR...
Purpose. Intracavernosal self-injection (ICI) was first described in 1982, and remains a viable therapy for erectile dysfunction. However, intracorporal needle breakage can be rare complication of therapy. We report retention 30-gauge 42-year-old paraplegic man. discuss our experience using portable high-frequency ultrasound intraoperatively to visualize guide removal retained ICI needle. Materials Methods. Review case technique are presented. Results. Using intraoperative imaging, the...
No AccessJournal of UrologyAdult Urology1 Nov 2013Perioperative Celecoxib Decreases Opioid Use in Patients Undergoing Testicular Surgery: A Randomized, Double-Blind, Placebo Controlled Trial Akanksha Mehta, Wayland Hsiao, Peggy King, and Peter N. Schlegel MehtaAkanksha Mehta More articles by this author , HsiaoWayland Hsiao KingPeggy King SchlegelPeter View All Author Informationhttps://doi.org/10.1016/j.juro.2013.04.058AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack...
Differences in prostate cancer incidence, grade and stage at diagnosis, survival black vs nonblack men are well documented. Recent studies indicate that lipids may have a role oncogenesis, including of cancer. We investigated the relationship between circulating patients, newly diagnosed cancer.The study population included consecutive patients who underwent biopsy for increased specific antigen and/or abnormal digital rectal examination Atlanta Veterans Affairs Medical Center. Age, race,...