- Advanced Fiber Laser Technologies
- Photonic and Optical Devices
- Antenna Design and Analysis
- Antenna Design and Optimization
- Orbital Angular Momentum in Optics
- Autophagy in Disease and Therapy
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Ferroptosis and cancer prognosis
- Advanced Antenna and Metasurface Technologies
- Photonic Crystal and Fiber Optics
- Acupuncture Treatment Research Studies
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Microwave Engineering and Waveguides
- Renal and Vascular Pathologies
- Advanced Photonic Communication Systems
- Optical Systems and Laser Technology
- Laser Applications in Dentistry and Medicine
- Telomeres, Telomerase, and Senescence
- Renal cell carcinoma treatment
- Radiation Dose and Imaging
- MRI in cancer diagnosis
Wuhan National Laboratory for Optoelectronics
2020-2023
Huazhong University of Science and Technology
2018-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2023
Tongji Hospital
2018-2022
Mitochondria are vital for energy production and redox homeostasis, yet knowledge of relevant mechanisms remains limited. Here, through a genome-wide CRISPR-Cas9 knockout screening, we have identified DMT1 as major regulator mitochondria membrane potential. Our findings demonstrate that deficiency increases the activity mitochondrial complex I reduces III. Enhanced leads to increased NAD+ production, which activates IDH2 by promoting its deacetylation via SIRT3. This results in higher levels...
Explosive growth in demand for data traffic has prompted exploration of the spatial dimension light waves, which provides a degree freedom to expand transmission capacity. Various techniques based on bulky optical devices have been proposed tailor waves dimension. However, their inherent large size, extra loss, and precise alignment requirements make these relatively difficult implement compact flexible way. In contrast, three-dimensional (3D) photonic chips with size low loss provide...
In this letter, a broadband low-profile dual circularly polarized reflectarray (dual-CP RA) for Ku-band satellite communications is proposed. A novel single-layer metasurface unit cell consisting of functional layer, an air layer and metal plate investigated first. The structure printed on the F4B substrate. can effectively extend bandwidth, overall profile only 0.12λ0, where λ0 represents wavelength at 11.725 GHz. To independently control phase left-handed (LHCP) right-handed (RHCP) waves,...
To investigate the subjective and quantitative image quality radiation exposure of CT enterography (CTE) examination performed at low tube voltage concentration contrast agent with adaptive statistical iterative reconstruction (ASIR) algorithm, compared conventional CTE.One hundred thirty-seven patients suspected or proved gastrointestinal diseases underwent enhanced CTE in a multidetector computed tomography (MDCT) scanner. All cases were assigned to 2 groups. Group A (n = 79) based on...
DNA damage is the major cause of senescence and apoptosis; however, manner by which DNA-damaged cells become senescent remains unclear. We demonstrate that leads to a greater level rather than apoptosis in DBC1-deficient cells. In addition, we show BLM becomes degraded during damage, induces p21 expression senescence. DBC1 binds shields from degradation, thus suppressing ML216 promotes DBC1–BLM interaction, aids preservation following suppresses enhances pulmonary function lowering levels...
Renal tumors are very common in the urinary system, and preoperative differential diagnosis of homogeneous renal remains a challenge. This study aimed to evaluate feasibility whole-lesion CT texture analysis for identification including clear cell carcinoma (ccRCC), chromophobe RCC (chRCC), oncocytoma (RO). retrospective was approved by our local IRB. Contrast-enhanced examination performed 128 patients histopathologically confirmed ccRCC, chRCC, RO. The one-way ANOVA test with Bonferroni...
Objective To design a laser acupuncture instrument with dual wavelength and multi-channel, under the guidance of traditional Chinese medicine theory according to low-level induced effect in bio-tissues compatibility characteristics points. Methods Using SCM semiconductor laser, hardware circuitry was designed achieve basic functions instrument, corresponding PC software developed. Results The treatment for several points could be carried out at same time or different parameters...
We demonstrate on-chip monolithically integrated hybrid (de)multiplexer with 4x32 channels for simultaneous mode- and wavelength-division multiplexing ultra-large capacity optical interconnect link. The chip consists of 4-channel mode 32-channel arrayed waveguide grating.
We demonstrate an all-fiber wavelength-switchable orbital angular momentum (OAM) laser assisted by fiber Bragg grating (FBG) and Fabry-Perot interferometer (FPI), which are directly inscribed femtosecond in ring-core erbium-doped fiber.