To explore the application value of computed tomography (CT) texture analysis in differentiating atypical pancreatic neuroendocrine tumors (pNET) from ductal adenocarcinomas (PDAC). This single-center retrospective study was approved by local institutional review board, and requirement for informed consent waived. We retrospectively analyzed 127 patients with 50 PDACs 77 pNETs pathology database between January 2012 May 2017.These successfully finished preoperative contrast-enhanced CT test....

Purpose To determine the utility of various diffusion parameters obtained from monoexponential, biexponential, and stretched exponential diffusion-weighted imaging (DWI) models in differentiating between minimal fat angiomyolipoma (MFAML) clear cell renal carcinoma (ccRCC). Materials Methods One hundred thirty-one patients with pathologically confirmed MFAML (n = 27) or ccRCC 104) underwent multi-b value DWI (0∼1700 s/mm2) at 3.0 Tesla MRI. An isotropic apparent coefficient (ADC) was...

The purpose of this article is to evaluate the utility volumetric histogram analysis apparent diffusion coefficient (ADC) derived from reduced-FOV DWI for small (≤ 4 cm) solid renal mass subtypes at 3-T MRI.This retrospective study included 38 clear cell carcinomas (RCCs), 16 papillary RCCs, 18 chromophobe 13 minimal fat angiomyolipomas (AMLs), and seven oncocytomas evaluated with preoperative MRI. Volumetric ADC maps were generated using all slices DW images obtain parameters, including...

To explore whether volumetric CT texture analysis (CTTA) can serve as a potential imaging biomarker for risk stratification of small bowel gastrointestinal stromal tumors (small bowel-GISTs).A total 90 patients with bowel-GISTs were retrospectively reviewed, these, 26 rated high risk, 13 intermediate and 51 low or very risk. Histogram parameters extracted from images compared among different levels by using one-way variance. Receiver operating characteristics (ROCs) areas under the curve...

To evaluate the application value of diffusion kurtosis imaging (DKI) for monitoring renal function and interstitial fibrosis.Forty-two patients suspected having primary nephropathy, hypertension or diabetes with impaired were examined DKI. DKI metrics cortex medulla on both sides each patient measured, including mean (MK), axial (Ka), radial (Kr), diffusivity (MD) fractional anisotropy (FA). The differences in between stable estimated glomerular filtration rate (eGFR) as well mild severe...

To quantitatively compare the monoexponential, biexponential, and stretched-exponential diffusion-weighted imaging (DWI) models in differentiating benign from malignant solid hepatic lesions. The institutional review board approved this retrospective study waived informed consent requirement. A total of 188 patients with 288 lesions included 202 86 were assessed (confirmed by pathology or clinical follow-up for 6 months). All underwent 3.0-T MRI, including multi-b DWI that used 12 b values....

To investigate the subjective and quantitative image quality radiation exposure of CT enterography (CTE) examination performed at low tube voltage concentration contrast agent with adaptive statistical iterative reconstruction (ASIR) algorithm, compared conventional CTE.One hundred thirty-seven patients suspected or proved gastrointestinal diseases underwent enhanced CTE in a multidetector computed tomography (MDCT) scanner. All cases were assigned to 2 groups. Group A (n = 79) based on...

Background: Altered patterns of bile acids (BAs) are frequently present in liver fibrosis, and BAs function as signaling molecules to initiate inflammatory responses. Silybin meglumine (SLB-M) is widely used treating various diseases including fibrosis. However, research on its effects acid (BA) metabolism limited. This study investigated the therapeutic SLB-M fibrosis BA a CCl4-induced murine model. Methods: A model was induced by CCl4. Fibrosis evaluated using HE, picrosirius red, Masson’s...

To investigate the value of combined chemical exchange saturation transfer (CEST) and conventional magnetization imaging (MT) in detecting metabolic structural changes renal fibrosis rats with unilateral ureteral obstruction (UUO) at 3T MRI. Thirty-five Sprague-Dawley underwent UUO surgery (n = 25) or sham 10). The obstructed contralateral kidneys were evaluated on days 1, 3, 5, 7 after surgery. After CEST MT examinations, 18F-labeled fluoro-2-deoxyglucose positron emission tomography was...

Abstract Objectives To explore the diagnostic performance of diffusion kurtosis imaging (DKI) in evaluating clinical and pathological characteristics patients with immunoglobulin A nephropathy (IgAN) compared conventional DWI. Materials methods total 28 IgAN 14 healthy volunteers prospectively underwent MRI examinations including coronal T2WI, axial T1WI, DWI sequences from September 2020 to August 2021. We measured mean (MK), diffusivity (MD), apparent coefficient (ADC) by using MR Body...

To investigate the potential of histogram analysis based on diffusion kurtosis imaging (DKI) in evaluating renal function and fibrosis associated with chronic kidney disease (CKD).Thirty-six CKD patients were enrolled, DKI was performed all before biopsy. The parameters diffusivity (D) (K) obtained using FireVoxel. between stable [estimated glomerular filtration rate (eGFR) ≥ 60 ml/min/1.73 m2] impaired (eGFR < m2) eGFR group compared. Besides, classified into mild, moderate, severe a...

Purpose The aim of this study was to investigate the effect using low tube voltage, low-concentration contrast media and adaptive statistical iterative reconstruction (ASIR) for reducing radiation iodine doses in adrenal nephrogenic hypertension patients. Methods materials A total 148 patients who were suspected lesions or renal artery stenoses assigned two groups and. Group (n=74) underwent a molecular weight dextran enhanced multi-detector row spiral CT (MDCT) (80 kVp, 270 mg I/mL agent),...

Abstract As the direct entrapment of camptothecin (CPT) into conventionally used polymeric materials is extremely difficult due to its high crystallization property, CPT‐derived prodrugs are widely increase drug‐polymer compatibility. However, rapid CPT conversion from still a challenge steric hindrance around hydroxyl CPT. To address this, we reported here fragile lactyl carbonate (LC) linker, which could be instantly cleaved release LC‐linked lipophilic under physiological conditions....

Abstract Rationale: Hepatoid adenocarcinoma (HAC) is a rare extrahepatic that histologically resembles hepatocellular carcinoma (HCC). HAC of peritoneal cavity can present as solitary mass or disseminated nodules indicating different treatment. Patient concerns: In this study, we the cases 29-year-old man and 64-year-old woman who suffered from HAC. Diagnosis: The serum alpha-fetoprotein (AFP) both patients ascites 1 patient were markedly elevated. One presented with multiple nodular in...

Abstract Aim To investigate the radiological characteristics of developmental anomalies right hepatic lobe and to systematically compare efficiency CT, MR ultrasound (US) imaging in revealing these disorders. Methods This retrospective study was approved by institutional review board, requirement for informed consent waived. or US clinical data 43 cases with were independently reviewed two experienced radiologists. Systematic comparative analysis MR, indicating main signs aplasia hypoplasia...

To improve understanding of diffusion weighted imaging (DWI) characteristic MRI and clinical variables, further optimize the Bosniak classification for diagnosis cystic renal masses (CRMs). This study retrospectively analyzed 130 CRMs in 125 patients with CT or MRI, including 87 DWI (b = 600, 1000 s/mm2). Clinical variables histopathological results were recorded. Two radiologists consensus images each lesion size, thickness wall, number septum, enhancement wall/septum, wall nodule, signal...

Objective To explore the utility of ADC histogram analysisin differentiation clear cell renal carcinoma(ccRCC)and non-clear carcinoma(non-ccRCC)with r-Fov DWI. Methods Sixty-six tumors(46 patients with 47 ccRCCs and 18 19 non-ccRCCs)in 64 patients, who underwent preoperative routine MRI sequences r-FOV DWI, were retrospectively evaluated. The whole-lesion values derived from anlysis(including mean, median, ADC_5th, ADC_25th, ADC_75th, ADC_95th, skew kurtosis)were measured for each...

With the rapid development of photovoltaic industry, service life and safety array have attracted more attention. If under fault is not diagnosed treated in time, it may cause fire other serious consequences. Therefore, study simulation diagnosis p-v arrays, has very important significance. In this paper, according to output characteristics different environments conditions, M file was written simulate complex light short circuit conditions shadow occlusion conditions. By studying curve...

Background: It is essential to discriminate low-grade (G1), intermediate-grade (G2) and high-grade (G3) rectal neuroendocrine tumors (R-NETs) due the treatment decisions postoperative management are totally different. CT histogram analysis, which a novel method provide objectively quantified assessment of tumor, may be helpful for differentiating grade R-NETs. Methods: A total 61 (35 G1, 12 G2 14 G3) patients who underwent preoperative contrast-enhanced treated with surgery confirmed as...