A5023879591- Phytochemistry and biological activity of medicinal plants
- Ion Channels and Receptors
- Ferroptosis and cancer prognosis
- Lung Cancer Treatments and Mutations
- Radioactivity and Radon Measurements
- Inflammatory Biomarkers in Disease Prognosis
- Epigenetics and DNA Methylation
- Phytochemicals and Antioxidant Activities
- Genomics, phytochemicals, and oxidative stress
- Airway Management and Intubation Techniques
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Antenna Design and Analysis
- Cancer Cells and Metastasis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Diet, Metabolism, and Disease
- Inflammasome and immune disorders
- Cancer therapeutics and mechanisms
- Cancer-related Molecular Pathways
- Muscle and Compartmental Disorders
- Electrospun Nanofibers in Biomedical Applications
- Muscle Physiology and Disorders
- Metal-Organic Frameworks: Synthesis and Applications
- Developmental Biology and Gene Regulation
- Fungal and yeast genetics research
First Affiliated Hospital of GuangXi Medical University
2018-2024
Guangxi Medical University
2018-2024
Shanghai Institute of Geological Survey
2023
Yunnan Metallurgical Group (China)
2023
Air Force Medical University
2019-2021
82th Hospital of Pla
2021
Nanjing University
2021
Central South University
2010-2019
Xiangya Hospital Central South University
2010-2019
Chengdu Medical College
2019
Increasing evidence has shown the effectiveness of surgery for stage IV non-small cell lung cancer (NSCLC). Present study aims to summarize experience our institution in dealing with advanced NSCLC context multimodality therapy including surgery.Patients underwent surgical resection diagnosed before or during from January 2014 June 2017 at Tangdu Hospital were included this study.There 88 patients enrolled study. Among them, 35 pleural metastases, 18 brain oligometastases, 25 extra-brain...
The landscape of cellular plasticity and sources with relevant niche signals in hepatocellular carcinoma is still obscure. Transient receptor potential vanilloid 1 (TRPV1), a non-selective cation channel, involved variety malignancies overexpressed (HCC). We have investigated the role TRPV1 HCC from different angles by various experimental techniques, such as vivo vitro experiments, bioinformatics analysis data genetic models induced diethylnitrosamine (DEN), mice samples human samples. find...
In our previous study, we reported that the cannabinoid receptors CB1 and CB2 are overexpressed in human hepatocellular carcinoma (HCC) tissues. Recently, antitumor potential of endogenous anandamide (AEA) has also been addressed. The present study was conducted to investigate anti-proliferative effects AEA HCC cells. cell line Huh7 used. Cell proliferation measured by MTT assay flow cytometry. Apoptotic analysis investigated TUNEL assay. Real-time PCR western blot were used analyze...
Therapeutic application of unmodified camptothecin (CPT) is severely restricted by its extremely low water solubility and the instability active lactone ring. In this study, a redox-sensitive CPT-OA conjugate containing disulfide bond (CPT-SS-OA) was used to deliver lactone-stabilized CPT for improved antitumor efficacy. A non-sensitive as control illuminate role bond. Both CPT-SS-OA formulated in cremophor EL micelles (CM) displayed multiple therapeutic advantages: small diameter (∼14 nm),...
Injectable hydrogels possess tremendous merits for use in muscle regeneration; however, they still lack intrinsic biological cues (such as the proliferation and differentiation of myogenic cells), thus considerably restricting their potential therapeutic use. Herein, we developed a double cross-linked injectable hydrogel composed methacrylamidated oxidized hyaluronic acid (MOHA) muscular decellularized matrix (MDM). The chemical composition was confirmed using 1H NMR Fourier transform...
With the development of economy and society, environmental problems caused by heavy metals have always been focus attention. Strong concern has recently shown for metal pollution soils in southwestern China. The surface Xinping area Yunnan province, China are surveyed along with some crop samples. There 3312 95 samples collected about 370 square kilometers. Heavy including As, Cd, Cr, Hg, Pb pH analyzed. New single integrated indices (PI PIn) crops (PIc PInc) based on Chinese criteria...
Numb, an endocytic adaptor, is a known cell fate determinant that participates in asymmetric division. The present study aimed to explore the potential roles of Numb hepatocarcinogenesis. expression was investigated hepatocellular carcinomas (HCC) with reverse transcription‑quantitative polymerase chain reaction and immunohistochemical examination; its association prognosis HCC patients analyzed. In addition, effects deletion on proliferation cells relevant molecules were evaluated Huh7...
High metastasis is a leading risk factor for the survival of non-small cell lung cancer (NSCLC) and epithelial-mesenchymal transition (EMT) vital step metastasis. The expression novel oncogene with kinase domain (NOK) has been observed in some human malignancies, including (NSCLC); however, biological function NOK NSCLC remains unclear. In study, we explored NSCLC, an aim to elucidate relevant underlying mechanisms.We investigate NOK, p-Akt, p-GSK-3β, E-cadherin N-cadherin by...
Abstract As the direct entrapment of camptothecin (CPT) into conventionally used polymeric materials is extremely difficult due to its high crystallization property, CPT‐derived prodrugs are widely increase drug‐polymer compatibility. However, rapid CPT conversion from still a challenge steric hindrance around hydroxyl CPT. To address this, we reported here fragile lactyl carbonate (LC) linker, which could be instantly cleaved release LC‐linked lipophilic under physiological conditions....
The trachea is the uppermost respiratory airway element connecting larynx to bronchi Airway reconstructions in humans are often developed from animal models but there limited knowledge comparing tracheal biomechanics between species. We aimed assess structure and of porcine, canine, caprine human airways.Tracheas pigs (n=15), goats (n=9) canines were divided into three groups (4, 6 8-ringswhile left principal brochi (n=12) two (3and-rings). structures compared using histology scanning...
Acute compartment syndrome (ACS) is a life-threatening orthopedic emergency, which can even result in amputation. Ferroptosis an iron-dependent form of nonapoptotic cell death. This study investigated the mechanism ferroptosis ACS, explored candidate markers, and determined effective treatments. identified pathways involved development ACS through gene set enrichment analysis (GSEA), Gene Ontology, Kyoto Encyclopedia Genes Genomes (KEGG), GSEA heme oxygenase 1 (Hmox1). Bioinformatics...
A low profile ultra-wideband tightly coupled dipole array is studied. The antenna elements are fed by Marchand baluns of small size and cost. metasurface based wide-angle impedance matching (MSWAIM) layer introduced to replace the traditional dielectric WAIM, improving beam scan performance reducing profile. simulation shows that proposed can operate over 2.4-12.4 GHz, approximately 5:1 bandwidth with maximum scanning angle 50o for both E plane 45o H plane. above ground only 0.578λH at...
The morphology and surface characteristics of yeast cells have important impacts on a yeast-wastewater treatment system. In this study, the effects supplement Ca2+, Mn2+, Mg2+, NH4 + settle ability, flocculation hydrophobicity Candida tropicalis (O2) lipolytica (G1) were investigated. Result shows that: different nutrient factors cell properties vary with srains, deficiency Mg2+ can induce G1 to transform hyphal which probably deteriorates cell's There is no manifest influence Ca2+ Mn2+...
Extremity compartment syndrome can cause neuromuscular ischemia and deposition of metabolites in the compartment, leading to irreversible lesions which harm limb functions end. It is a great challenge for surgeons make timely accurate diagnosis adults children. The key evaluation clinical symptoms intracompartmental pressure. In this paper we summarize epidemiology, etiology, pathophysiology, current treatment acute extremity upper lower extremities children. Key words: Compartment...