Xue Fan

ORCID: 0000-0001-6406-7245
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Research Areas
  • Kawasaki Disease and Coronary Complications
  • Cancer-related molecular mechanisms research
  • Abdominal vascular conditions and treatments
  • Dental Health and Care Utilization
  • Immune Cell Function and Interaction
  • Aortic Disease and Treatment Approaches
  • Geomechanics and Mining Engineering
  • Ferroptosis and cancer prognosis
  • Robotics and Sensor-Based Localization
  • Cancer, Lipids, and Metabolism
  • Gut microbiota and health
  • Intermetallics and Advanced Alloy Properties
  • High Temperature Alloys and Creep
  • 3D Surveying and Cultural Heritage
  • Spinal Fractures and Fixation Techniques
  • Systemic Sclerosis and Related Diseases
  • Genomics and Chromatin Dynamics
  • Genetics and Neurodevelopmental Disorders
  • Genomic variations and chromosomal abnormalities
  • Drug-Induced Hepatotoxicity and Protection
  • Circular RNAs in diseases
  • Gastric Cancer Management and Outcomes
  • Drug Transport and Resistance Mechanisms
  • Cervical and Thoracic Myelopathy
  • Osteoarthritis Treatment and Mechanisms

Ningxia Medical University
2025

Southwest Hospital
2024

Ningxia Hui Autonomous Region Peoples Hospital
2024

Shanghai University of Traditional Chinese Medicine
2024

Guangdong Academy of Medical Sciences
2023-2024

Guangdong Provincial People's Hospital
2023-2024

China Pharmaceutical University
2022-2024

Army Medical University
2024

Sichuan University
2023-2024

Southern Medical University
2021-2024

In this work, we report a synthesis approach for catalyst preparation using shape-controlled Al2O3 supports with enriched quantities of coordinatively unsaturated Al3+ centers. These centers can then induce ordering in bimetallic catalysts, even simple impregnation strategy and is shown to be beneficial selective hydrogenation acetylene. Interestingly, nanorod induced highly homogeneous ordered Ni1Cu1 nanoalloy, mainly attributed the coordination effect sites that accelerate atomic diffusion...

10.1021/acscatal.2c06091 article EN ACS Catalysis 2023-01-19

Cisplatin resistance (DDP-resistance) remains one of the major causes poor prognosis in females with ovarian cancer. Long non-coding RNAs (lncRNAs) have been shown to participate regulation cellular processes, including chemoresistance. The aim this study was explore role HOX transcript antisense RNA (HOTAIR) DDP-resistant cancer cells.DDP-resistant cell lines (SKOV3/DDP and A2780/DDP) were established. Real-time PCR, western blot, dual-luciferase reporter assay, flow cytometry then used...

10.1186/s40659-020-00286-3 article EN cc-by Biological Research 2020-04-29

In this paper, an ultra-high sensitive plasmonic sensor is theoretically proposed for refractive index based on D-shaped photonic crystal fiber (PCF) with graphene-coated Ag-grating in mid-infrared region. Surface plasmon polariton at the metal/dielectric interface can be effectively excited by fundamental guiding mode, leading to surrounding medium-dependent loss spectrum. This metallic-grating PCF exhibits a maximum sensitivity of 18612 nm/RIU detection resolution 4.16 × 10-6 RIU range...

10.1016/j.heliyon.2023.e14921 article EN cc-by Heliyon 2023-03-28

Abstract Highly dispersed Pt‐bimetallic sub‐nanometer catalysts are crucial for efficient propane dehydrogenation (PDH), but synthesizing them with cost‐effective Pt precursors is challenging due to Pt's tendency agglomerate, reducing catalytic activity. This study presents a Cs + ‐mediated vacancy‐anchoring strategy fabricate aggregates (CsPtM, M = Sn, V, Cr, Zn, Ga, Mn, Nb, Cu, and In) supported on Al₂O₃. ions selectively occupy cationic vacancies the Al₂O₃ surface, which serves anchor...

10.1002/aic.18756 article EN AIChE Journal 2025-01-31

To investigate the prognostic significance of preoperative albumin to globulin ratio (AGR) in patients with resectable gastric cancer (GC).According inclusion criteria, 269 GC (male:female=127:67; median age: 67 years) a stage I through III who underwent gastrectomy D2 lymphadenectomy and R0 resection were included. These categorized into two groups, namely low AGR group high group, based on cutoff point that was obtained using receiver-operating characteristic curve. The correlations...

10.5152/tjg.2017.17167 article EN The Turkish Journal of Gastroenterology 2017-10-25

Nutrition and energy are essential for poultry growth production performance. Fasting refeeding have been widely used to study the effects of nutrition, energy, related mechanisms in chicken. Previous studies shown that geese a strong capacity fat synthesis storage; thus, changes goose liver transcriptome may be different from those chicken assessed with model fasting refeeding. However, responses not yet addressed. In this study, 36 70-day-old Si Ji similar body weight were randomly...

10.2141/jpsa.0200095 article EN cc-by-nc-sa The Journal of Poultry Science 2021-01-01

Metabolism reprogramming within the tumor microenvironment (TME) can have a profound impact on immune cells. Identifying association between metabolic phenotypes and cells in lung adenocarcinoma (LUAD) may reveal mechanisms of resistance to checkpoint inhibitors (ICIs). Metabolic were classified by expression genes. Somatic mutations transcriptomic features compared across different phenotypes. The phenotype LUAD is predominantly determined reductase-oxidative activity divided into two...

10.1080/2162402x.2024.2340154 article EN cc-by-nc OncoImmunology 2024-04-09

Background: Altered patterns of bile acids (BAs) are frequently present in liver fibrosis, and BAs function as signaling molecules to initiate inflammatory responses. Silybin meglumine (SLB-M) is widely used treating various diseases including fibrosis. However, research on its effects acid (BA) metabolism limited. This study investigated the therapeutic SLB-M fibrosis BA a CCl4-induced murine model. Methods: A model was induced by CCl4. Fibrosis evaluated using HE, picrosirius red, Masson’s...

10.3390/metabo14100556 article EN cc-by Metabolites 2024-10-17

Background: Ovarian cancer (OC) is the most prevalent gynecologic malignancy, with high mortality rates. However, its pathogenesis remains unclear. The current study aimed to explore potential biomarkers and suppressor genes for diagnosing treating OC. Methods: Biochemical bioinformatics approaches were used detect differentially expressed (DEGs) in ovarian tissues via integration analysis. Kaplan-Meier plot analysis was performed assess progression-free survival overall according DEGs....

10.2174/1386207326666230301141912 article EN Combinatorial Chemistry & High Throughput Screening 2023-03-01

It is known that nutrition and immunity are connected, but the mechanism not very clear. Endogenous retroviruses (ERV) account for 8 to 10% of human mouse genomes play an important role in some biological processes animals. Recent studies indicate activation ERV can affect expression immunity- or inflammation-related genes, activities subjected regulation many factors including nutritional factors. Therefore, we hypothesize status genes via ERV. To verify this hypothesis, animals was altered...

10.1016/j.psj.2020.11.057 article EN cc-by-nc-nd Poultry Science 2020-12-02

Objective: The current study was to evaluate the prevalence of increased carotid artery intimal-medial thickness (IMT) and plaque in young individuals factors associated with IMT were also assessed. Methods: Individuals between 18 44 years old who underwent an annual health examination without cardiovascular disease included. value ≥ 0.1 cm defined as 0.15 plaque. Based on IMT, participants divided into normal abnormal groups. Results: A total 551 included mean age 38.9 old, women accounting...

10.2147/ijgm.s360437 article EN cc-by-nc International Journal of General Medicine 2022-05-01

Background: There are few studies focusing on biomechanism of spinal cord injury according to the ossification posterior longitudinal ligament (OPLL) during cervical rotatory manipulation (CRM). This study aimed explore biomechanical effects CRM cord, dura matter and nerve roots with OPLL in vertebral canal. Methods: Three validated FE models craniocervical spine complex were constructed by adding mild, moderate, severe healthy model, respectively. We simulated static compression dynamic...

10.3389/fbioe.2023.1095587 article EN cc-by Frontiers in Bioengineering and Biotechnology 2023-01-13

This study aimed to analyze the molecular characteristics of gastric adenocarcinoma fundic-gland type (GAFG) and explore possible mechanism tumor development. Samples from 10 Chinese patients with GAFG were collected at Peking University International Hospital Liaocheng People's between January 2015 March 2022. The nucleic acid sequence Epstein Barr virus-encoded RNA (EBV-EBER) was detected by in situ hybridization. Genetic mutation information for GNAS, KRAS, NRAS, BRAF, PIK3CA, TP53, APC,...

10.3892/mco.2023.2678 article EN Molecular and Clinical Oncology 2023-08-31

Little information is available concerning the biomechanism involved in spinal cord injury after cervical rotatory manipulation (CRM). The primary purpose of this study was to explore biomechanical and kinematic effects CRM on a healthy cord.A finite element (FE) model basilaris cranii, C1-C7 vertebral bodies, nerve root complex canal contents constructed validated against vivo vitro published data. FE simulated flexion, extension neutral positions. stress distribution, forma relative...

10.1186/s13018-021-02885-6 article EN cc-by Journal of Orthopaedic Surgery and Research 2021-12-24

Breast cancer can metastasize to other organs following initial treatment.Bones, liver, and the lung are most common sites of breast metastases.The digestive tract, on hand, is rarely involved.The incidence mesorectal metastasis (a special category rectal metastases) from has not been described before.The case reported herein concerns a 68-year-old woman who underwent mastectomy.A pelvic mass with no symptoms was subsequently identified by computed tomography in patient.We ultimately...

10.3748/wjg.v21.i14.4408 article EN cc-by-nc World Journal of Gastroenterology 2015-01-01

Introduction CD8 + T cell tolerance plays an important role in tumor escape. Recent studies have shown that CD45 erythroid progenitor cells (CD45 EPCs) generated through splenic extramedullary erythropoiesis suppress immunity. However, the mechanism underlying how EPCs mediate remains incompletely understood and requires further research. Methods In this study, antigen-processing abilities of was verified both vitro vivo experiments. We used method co-culture adoptive transfer experiments to...

10.3389/fimmu.2024.1381919 article EN cc-by Frontiers in Immunology 2024-05-10
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