Andrey G Azov
- Genomics and Phylogenetic Studies
- Molecular Biology Techniques and Applications
- Bioinformatics and Genomic Networks
- RNA and protein synthesis mechanisms
- Infectious Diseases and Tuberculosis
- CRISPR and Genetic Engineering
- RNA modifications and cancer
- Helicobacter pylori-related gastroenterology studies
- Genetic Mapping and Diversity in Plants and Animals
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Microbial Community Ecology and Physiology
- Biomedical Text Mining and Ontologies
European Bioinformatics Institute
2019-2024
Aarhus University Hospital
2005
Sechenov University
2005
Ensembl (https://www.ensembl.org) is unique in its flexible infrastructure for access to genomic data and annotation. It has been designed efficiently deliver annotation at scale all eukaryotic life, it also provides deep comprehensive key species. Genomes representing a greater diversity of species are increasingly being sequenced. In response, we have focussed our recent efforts on expediting the new assemblies. Here, report release greatest annual number newly annotated genomes history...
Abstract The Ensembl project (https://www.ensembl.org) annotates genomes and disseminates genomic data for vertebrate species. We create detailed comprehensive annotation of gene structures, regulatory elements variants, enable comparative genomics by inferring the evolutionary history genes genomes. Our integrated are made available in a variety ways, including genome browsers, search interfaces, specialist tools such as Variant Effect Predictor, download files programmatic interfaces....
The Ensembl (https://www.ensembl.org) is a system for generating and distributing genome annotation such as genes, variation, regulation comparative genomics across the vertebrate subphylum key model organisms. pipeline capable of integrating experimental reference data from multiple providers into single integrated resource. Here, we present 94 newly annotated re-annotated genomes, bringing total number genomes offered by to 227. This represents largest expansion resource since its...
Ensembl (https://www.ensembl.org) has produced high-quality genomic resources for vertebrates and model organisms more than twenty years. During that time, our resources, services tools have continually evolved in line with both the publicly available genome data downstream research applications utilise platform. In recent years we witnessed a dramatic shift landscape. There been large increase number of reference genomes through global biodiversity initiatives. parallel, there major...
Abstract Ensembl Genomes (https://www.ensemblgenomes.org) provides access to non-vertebrate genomes and analysis complementing vertebrate resources developed by the project (https://www.ensembl.org). The two collectively present genome annotation through a consistent set of interfaces spanning tree life presenting sequence, annotation, variation, transcriptomic data comparative analysis. Here, we our largest increase in plant, metazoan fungal since project's inception creating one world's...
Abstract Ensembl (https://www.ensembl.org) is a freely available genomic resource that has produced high-quality annotations, tools, and services for vertebrates model organisms more than two decades. In recent years, there been dramatic shift in the landscape, with large increase number phylogenetic breadth of reference genomes, alongside major advances pan-genome representations higher species. order to support these efforts accelerate downstream research, continues focus on scaling rapid...
Ensembl (www.ensembl.org) is an open platform integrating publicly available genomics data across the tree of life with a focus on eukaryotic species related to human health, agriculture and biodiversity. This year has seen continued expansion in number represented, >4800 >31 300 prokaryotic genomes available. The new site, currently beta, develop, holding >2700 genome assemblies. site provides genome, gene, transcript, homology variation views, will replace current Rapid Release site; this...
Traditional histological diagnosis of mycobacterial infection in formalin‐fixed and paraffin‐embedded (FFPE) tissues is insensitive poorly specific. To improve this, we developed nested polymerase chain reaction (PCR) protocols for detecting a Mycobacterium genus‐specific 65‐kDa heat shock protein (HSP65) sequence the M. tuberculosis complex‐specific insertion IS6110 FFPE sections. Protocols were optimized on from 20 patients with final clinical infection. Amplicons controlled by sequencing...