Andrés Becerra
- Bioinformatics and Genomic Networks
- Biomedical Text Mining and Ontologies
- Genomics and Phylogenetic Studies
- Genetics, Aging, and Longevity in Model Organisms
- Evolution and Genetic Dynamics
- Molecular Biology Techniques and Applications
- Microbial Community Ecology and Physiology
- Protein Structure and Dynamics
- Gene expression and cancer classification
- Genetics, Bioinformatics, and Biomedical Research
- HIV Research and Treatment
- Single-cell and spatial transcriptomics
- CRISPR and Genetic Engineering
- Genomics and Rare Diseases
- RNA and protein synthesis mechanisms
European Bioinformatics Institute
2021-2024
Wellcome Trust
2022-2024
Universidad del Valle
2017
Abstract Ensembl Genomes (https://www.ensemblgenomes.org) provides access to non-vertebrate genomes and analysis complementing vertebrate resources developed by the project (https://www.ensembl.org). The two collectively present genome annotation through a consistent set of interfaces spanning tree life presenting sequence, annotation, variation, transcriptomic data comparative analysis. Here, we our largest increase in plant, metazoan fungal since project's inception creating one world's...
Abstract WormBase (www.wormbase.org) is the central repository for genetics and genomics of nematode Caenorhabditis elegans. We provide research community with data tools to facilitate use C. elegans related nematodes as model organisms studying human health, development, many aspects fundamental biology. Throughout our 22-year history, we have continued evolve reflect progress innovation in science technologies involved study strive incorporate new types richer sets, integrated displays...
The Alliance of Genome Resources (the Alliance) is a combined effort 7 knowledgebase projects: Saccharomyces Database, WormBase, FlyBase, Mouse the Zebrafish Information Network, Rat and Gene Ontology Resource. seeks to provide several benefits: better service various communities served by these projects; harmonized view data for all biomedical researchers, bioinformaticians, clinicians, students; more sustainable infrastructure. has cross-organism useful comparative views gene function,...
Abstract WormBase has been the major repository and knowledgebase of information about genome genetics Caenorhabditis elegans other nematodes experimental interest for over 2 decades. We have 3 goals: to keep current with fast-paced C. research, provide better integration resources, be sustainable. Here, we discuss state as well progress plans moving core infrastructure Alliance Genome Resources (the Alliance). As an member, will continue interact community, develop new features needed,...
Abstract The Alliance of Genome Resources (Alliance) is an extensible coalition knowledgebases focused on the genetics and genomics intensively studied model organisms. organized as individual knowledge centers with strong connections to their research communities a centralized software infrastructure, discussed here. Model organisms currently represented in are budding yeast, Caenorhabditis elegans, Drosophila, zebrafish, frog, laboratory mouse, rat, Gene Ontology Consortium. project rapid...
Short linear motifs in host organisms proteins can be mimicked by viruses to create protein-protein interactions that disable or control metabolic pathways. Given viral motif instances of regular expressions found chance, it is necessary develop filtering methods functional motifs. We conduct a systematic comparison computational approach for predicting motif-mediated between human and the immunodeficiency virus 1 (HIV-1). implemented three obtain sets: 1) conserved (C), 2) located...
Abstract The Alliance of Genome Resources (Alliance) is an extensible coalition knowledgebases focused on the genetics and genomics intensively-studied model organisms. organized as individual knowledge centers with strong connections to their research communities a centralized software infrastructure, discussed here. Model organisms currently represented in are budding yeast, C. elegans , Drosophila zebrafish, frog, laboratory mouse, rat, Gene Ontology Consortium. project rapid development...