A5004162519- Complex Network Analysis Techniques
- Opinion Dynamics and Social Influence
- Biomedical Text Mining and Ontologies
- Social Media and Politics
- Opportunistic and Delay-Tolerant Networks
- Bioinformatics and Genomic Networks
- Genetics, Aging, and Longevity in Model Organisms
- Caching and Content Delivery
- Human Mobility and Location-Based Analysis
- Single-cell and spatial transcriptomics
- Mobile Crowdsensing and Crowdsourcing
- Mobile Ad Hoc Networks
- Genetics, Bioinformatics, and Biomedical Research
- Impact of Technology on Adolescents
- Misinformation and Its Impacts
- Gene expression and cancer classification
- Genomics and Phylogenetic Studies
- Genomics and Rare Diseases
- Recommender Systems and Techniques
- Evolution and Genetic Dynamics
- Social Capital and Networks
- Research Data Management Practices
- Scientific Computing and Data Management
- Video Analysis and Summarization
- Natural Language Processing Techniques
California Institute of Technology
2017-2025
Institute of Informatics and Telematics
2011-2021
National Research Council
2013-2017
University of Oxford
2015
National Academies of Sciences, Engineering, and Medicine
2013
We use data on frequencies of bi-directional posts to define edges (or relationships) in two Facebook datasets and a Twitter dataset these create ego-centric social networks. explore the internal structure networks determine whether they have same kind layered as has been found offline face-to-face (which distinctively scaled with successively inclusive layers at 5, 15, 50 150 alters). The are best described by four-layer five-layer structure. absolute sizes mean contact alters within each...
Abstract WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as model system for studies across broad range of basic biological processes. Toward this mission, efforts are arranged in three primary facets: curation, user interface and architecture. In update, we describe progress each these areas. particular, discuss status literature curation recently added data, detail new features web options...
Abstract WormBase (www.wormbase.org) is the central repository for genetics and genomics of nematode Caenorhabditis elegans. We provide research community with data tools to facilitate use C. elegans related nematodes as model organisms studying human health, development, many aspects fundamental biology. Throughout our 22-year history, we have continued evolve reflect progress innovation in science technologies involved study strive incorporate new types richer sets, integrated displays...
WormBase (http://www.wormbase.org) is an important knowledge resource for biomedical researchers worldwide. To accommodate the ever increasing amount and complexity of research data, continues to advance its practices on data acquisition, curation retrieval most effectively deliver comprehensive about Caenorhabditis elegans, genomic information other nematodes parasitic flatworms. Recent notable enhancements include user-directed submission such as micropublication; presentation, including...
Abstract The Alliance of Genome Resources (Alliance) is a consortium the major model organism databases and Gene Ontology that guided by vision facilitating exploration related genes in human well-studied organisms providing highly integrated comprehensive platform enables researchers to leverage extensive body genetic genomic studies these organisms. Initiated 2016, building central portal (www.alliancegenome.org) for access data primary along with gene ontology data. All types represented...
The Alliance of Genome Resources (the Alliance) is a combined effort 7 knowledgebase projects: Saccharomyces Database, WormBase, FlyBase, Mouse the Zebrafish Information Network, Rat and Gene Ontology Resource. seeks to provide several benefits: better service various communities served by these projects; harmonized view data for all biomedical researchers, bioinformaticians, clinicians, students; more sustainable infrastructure. has cross-organism useful comparative views gene function,...
Abstract WormBase has been the major repository and knowledgebase of information about genome genetics Caenorhabditis elegans other nematodes experimental interest for over 2 decades. We have 3 goals: to keep current with fast-paced C. research, provide better integration resources, be sustainable. Here, we discuss state as well progress plans moving core infrastructure Alliance Genome Resources (the Alliance). As an member, will continue interact community, develop new features needed,...
Abstract The Alliance of Genome Resources (Alliance) is an extensible coalition knowledgebases focused on the genetics and genomics intensively studied model organisms. organized as individual knowledge centers with strong connections to their research communities a centralized software infrastructure, discussed here. Model organisms currently represented in are budding yeast, Caenorhabditis elegans, Drosophila, zebrafish, frog, laboratory mouse, rat, Gene Ontology Consortium. project rapid...
Results about offline social networks demonstrated that the relationships an individual (ego) maintains with other people (alters) can be organised into different groups according to ego network model. In this model seen as centre of a series layers increasing size. Social between and alters in close are stronger than those belonging more external layers. Online Networks becoming fundamental medium for humans manage their life, however structure these virtual environments has not been...
The extremely pervasive nature of mobile technologies, together with the user's need to continuously interact her personal devices and be always connected, strengthen user-centric approach design develop new communication computing solutions. Nowadays users not only represent final utilizers technology, but they actively contribute its evolution by assuming different roles: act as humans, sharing contents experiences through social networks, virtual sensors, moving freely in environment...
The growing popularity of Online Social Networks (OSN) is generating a large amount communication records that can be easily accessed and analysed to study human social behaviour. This represents unique opportunity understand properties networks were impossible assess in the past. Although analyses on OSN conducted hitherto revealed some important global networks, there still lack understanding mechanisms underpinning these properties, their relation behaviour, dynamic evolution over time....
Online Social Networks are amongst the most important platforms for maintaining social relationships online, supporting content generation and exchange between users. They therefore natural candidate to be basis of future humancentric networks data systems, in addition novel forms Internet services exploiting properties human relationships. Understanding structural OSN how they influenced by behaviour is thus fundamental design such human-centred systems. In this paper we analyse a real...
Abstract Short paragraphs that describe gene function, referred to as summaries, are valued by users of biological knowledgebases for the ease with which they convey key aspects function. Manual curation while desirable, is difficult sustain. We developed an algorithm uses curated, structured data at Alliance Genome Resources (Alliance; www.alliancegenome.org) automatically generate summaries simulate natural language. The used this purpose include curated associations (annotations) ontology...
Biological knowledgebases are essential resources for biomedical researchers, providing ready access to gene function and genomic data. Professional, manual curation of knowledgebases, however, is labor-intensive thus high-performing machine learning methods that improve biocuration efficiency needed. Here we report on sentence-level classification identify biocuration-relevant sentences in the full text published references two data types: expression protein kinase activity. We performed a...
We present two web apps for interactively performing common tasks with single-cell RNA sequencing data: scdefg differential expression and wormcells-viz visualization of gene expression. deployed these tools public Caenorhabditis elegans datasets curated by WormBase at https://single-cell.wormbase.org. Source code deploying other is available https://github.com/WormBase/scdefg https://github.com/WormBase/wormcells-viz.Supplementary data are Bioinformatics Advances online.
Opportunistic Mobile Social Networks represent the emerging trend in mobile applications combining novel paradigm of opportunistic networking with need users to generate and share contents anywhere anytime. In this demo we present a real implementation context-aware middleware for development optimized Networks. To highlight advantages platform also an innovative application tourists aimed at enriching touristic experience useful information virtual social interactions other users.
Abstract Biological knowledgebases rely on expert biocuration of the research literature to maintain up-to-date collections data organized in machine-readable form. To enter information into knowledgebases, curators need follow three steps: (i) identify papers containing relevant data, a process called triaging; (ii) recognize named entities; and (iii) extract curate accordance with underlying models. WormBase (WB), authoritative repository for Caenorhabditis elegans other nematodes, uses...