Anne Eagle

ORCID: 0000-0002-6271-5250
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About
Contact & Profiles
Research Areas
  • Biomedical Text Mining and Ontologies
  • Genetics, Bioinformatics, and Biomedical Research
  • Bioinformatics and Genomic Networks
  • Genomics and Phylogenetic Studies
  • Single-cell and spatial transcriptomics
  • Genomics and Rare Diseases
  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • Gene expression and cancer classification
  • Machine Learning in Bioinformatics
  • Mitochondrial Function and Pathology
  • Cancer-related molecular mechanisms research
  • Research Data Management Practices
  • Zebrafish Biomedical Research Applications

University of Oregon
2012-2022

ZFIN, the Zebrafish Model Organism Database (http://zfin.org), is central resource for zebrafish genetic, genomic, phenotypic and developmental data. ZFIN curators manually curate integrate comprehensive data involving genes, mutants, transgenics, phenotypes, genotypes, gene expressions, morpholinos, antibodies, anatomical structures publications. Integrated views of these data, as well gathered through collaborations exchanges, are provided a wide selection web-based search forms. Among...

10.1093/nar/gks938 article EN cc-by-nc Nucleic Acids Research 2012-10-15

Abstract The Alliance of Genome Resources (Alliance) is a consortium the major model organism databases and Gene Ontology that guided by vision facilitating exploration related genes in human well-studied organisms providing highly integrated comprehensive platform enables researchers to leverage extensive body genetic genomic studies these organisms. Initiated 2016, building central portal (www.alliancegenome.org) for access data primary along with gene ontology data. All types represented...

10.1093/nar/gkz813 article EN cc-by Nucleic Acids Research 2019-09-19

The Zebrafish Information Network (zfin.org) is the central repository for Danio rerio genetic and genomic data. has served zebrafish research community since 1994, expertly curating, integrating, displaying Key data types available at include, but are not limited to, genes, alleles, human disease models, gene expression, phenotype, function. makes Findable, Accessible, Interoperable, Reusable through nomenclature, curatorial annotation activities, web interfaces, downloads. Recently, 6...

10.1093/genetics/iyac016 article EN cc-by-nc-nd Genetics 2022-02-15
Julie Agapite Laurent‐Philippe Albou Suzi Aleksander Micheal Alexander Anna V. Anagnostopoulos and 95 more Giulia Antonazzo Joanna Argasinska Valerio Arnaboldi Helen Attrill Andrés Becerra Susan M. Bello Judith A. Blake Olin Blodgett Yvonne M. Bradford Carol J. Bult Scott Cain Brian R. Calvi Seth Carbon Juancarlos Chan Wen J. Chen J. Michael Cherry Jaehyoung Cho Karen Christie Madeline A. Crosby Paul A. Davis Eduardo da Veiga Beltrame Jeffrey L De Pons Peter D’Eustachio Stavros Diamantakis M. Eileen Dolan Gilberto dos Santos Eric Douglass Barbara Dunn Anne Eagle Dustin Ebert Stacia R. Engel David Fashena Saoirse Foley Ken Frazer Sibyl Gao Adam C Gibson Felix Gondwe Josh Goodman L. Sian Gramates Christian A Grove Paul Hale Todd Harris G. Thomas Hayman David P. Hill Douglas G. Howe Kevin Howe Yanhui Hu Sagar Jha James A. Kadin Thomas C. Kaufman Patrick Kalita Kalpana Karra Ranjana Kishore Anne E. Kwitek Stanley J. F. Laulederkind Raymond Lee Ian Longden Manuel Luypaert Kevin MacPherson Ryan Martin Steven J Marygold Beverley Matthews Monica McAndrews Gillian Millburn Stuart R. Miyasato Howie Motenko Sierra Moxon Hans‐Michael Müller Chris Mungall Anushya Muruganujan Tremayne Mushayahama Harika S Nalabolu Robert S Nash Patrick Ng Paulo Nuin Holly Paddock Michael Paulini Norbert Perrimon Christian Pich Mark Quinton-Tulloch Daniela Raciti Sridhar Ramachandran Joel E. Richardson Susan Russo Gelbart Leyla Ruzicka Kevin Schaper Gary Schindelman Mary Shimoyama Matt Simison David Shaw Ajay Shrivatsav Amy Singer Marek S. Skrzypek Constance M. Smith Cynthia L. Smith

The Alliance of Genome Resources (the Alliance) is a combined effort 7 knowledgebase projects: Saccharomyces Database, WormBase, FlyBase, Mouse the Zebrafish Information Network, Rat and Gene Ontology Resource. seeks to provide several benefits: better service various communities served by these projects; harmonized view data for all biomedical researchers, bioinformaticians, clinicians, students; more sustainable infrastructure. has cross-organism useful comparative views gene function,...

10.1093/genetics/iyac022 article EN cc-by Genetics 2022-02-25

The Zebrafish Model Organism Database (ZFIN; https://zfin.org) is the central resource for genetic, genomic, and phenotypic data zebrafish (Danio rerio) research. ZFIN continuously assesses trends in research, adding new types providing repositories tools that members of research community can use to navigate data. many advantages flexibility manipulation have made them an increasingly attractive animal model study human disease.To facilitate disease-related developed support provide disease...

10.1093/ilar/ilw040 article EN cc-by-nc ILAR Journal 2016-12-20

The Zebrafish Information Network (ZFIN) (https://zfin.org/) is the database for model organism, zebrafish (Danio rerio). ZFIN expertly curates, organizes and provides a wide array of genetic genomic data, including genes, alleles, transgenic lines, gene expression, function, mutant phenotypes, orthology, human disease models, nomenclature reagents. New features at include increased support regions non-coding more expressive Gene Ontology annotations. has recently taken over maintenance...

10.1093/nar/gky1090 article EN cc-by-nc Nucleic Acids Research 2018-10-26

Zebrafish, a popular organism for studying embryonic development and modeling human diseases, has so far lacked systematic functional annotation program akin to those in other animal models. To address this, we formed the international DANIO-CODE consortium created central repository store process zebrafish developmental genomic data. Our data coordination center ( https://danio-code.zfin.org ) combines total of 1,802 sets unpublished re-analyzed published data, which used improve existing...

10.1038/s41588-022-01089-w article EN cc-by Nature Genetics 2022-07-01

The Zebrafish Model Organism Database (ZFIN; http://zfin.org) is the central resource for genetic and genomic data from zebrafish (Danio rerio) research. ZFIN staff curate detailed information about genes, mutants, genotypes, reporter lines, sequences, constructs, antibodies, knockdown reagents, expression patterns, phenotypes, gene product function, orthology publications. Researchers can submit mutant, transgenic, expression, phenotype directly to use Community Wiki share antibody protocol...

10.1002/dvg.22868 article EN genesis 2015-06-20

The Zebrafish Model Organism Database (ZFIN; http://zfin.org) is the central resource for zebrafish (Danio rerio) genetic, genomic, phenotypic and developmental data. ZFIN curators provide expert manual curation integration of comprehensive data involving genes, mutants, transgenic constructs lines, phenotypes, genotypes, gene expressions, morpholinos, TALENs, CRISPRs, antibodies, anatomical structures, models human disease publications. We integrate curated, directly submitted,...

10.1093/nar/gkw1116 article EN cc-by-nc Nucleic Acids Research 2016-10-27

The Zebrafish Information Network (ZFIN) (https://zfin.org/) is the database for model organism, zebrafish (Danio rerio). ZFIN expertly curates, organizes, and provides a wide array of genetic genomic data, including genes, alleles, transgenic lines, gene expression, function, mutant phenotypes, orthology, human disease models, nomenclature, reagents. New features at include major updates to home page page, two most used pages ZFIN. Data mutants function continue be contributed Alliance...

10.1093/nar/gkaa1010 article EN cc-by Nucleic Acids Research 2020-10-14

Abstract Zebrafish, a popular model for embryonic development and modelling human diseases, has so far lacked systematic functional annotation programme akin to those in other animal models. To address this, we formed the international DANIO-CODE consortium created first central repository store process zebrafish developmental genomic data. Our Data Coordination Center ( https://danio-code.zfin.org ) combines total of 1,802 sets unpublished reanalysed published genomics data, which used...

10.1101/2021.08.09.454869 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-08-09

Abstract The Zebrafish Information Network (ZFIN, zfin.org ) is the central repository for zebrafish genetic and genomic data. ZFIN expertly curates, integrates, displays data including genes, alleles, human disease models, gene expression, phenotype, function, orthology, morpholino, CRISPR, TALEN, antibodies. makes research Findable, Accessible, Interoperable, Reusable (FAIR) through nomenclature, curatorial annotation activities, web interfaces, downloads. a founding member of Alliance...

10.1101/2021.09.22.461443 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2021-09-24
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