Aleena Mushtaq
A5040228960- Genomics and Phylogenetic Studies
- Molecular Biology Techniques and Applications
- RNA and protein synthesis mechanisms
- Bioinformatics and Genomic Networks
- Genomics and Rare Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Fire effects on ecosystems
- Plant responses to elevated CO2
- Genetic Associations and Epidemiology
- Food composition and properties
- Lipid metabolism and biosynthesis
- Genetic Mapping and Diversity in Plants and Animals
- Diet and metabolism studies
- Nutritional Studies and Diet
- Genetics, Bioinformatics, and Biomedical Research
- Gene expression and cancer classification
- Adipose Tissue and Metabolism
- Microbial Community Ecology and Physiology
- Birth, Development, and Health
- Global Health and Epidemiology
- Forest Insect Ecology and Management
- CRISPR and Genetic Engineering
European Bioinformatics Institute
2021-2025
University of East Anglia
2021
King's College London
2017
University of Agriculture Faisalabad
2014
Ensembl (https://www.ensembl.org) is unique in its flexible infrastructure for access to genomic data and annotation. It has been designed efficiently deliver annotation at scale all eukaryotic life, it also provides deep comprehensive key species. Genomes representing a greater diversity of species are increasingly being sequenced. In response, we have focussed our recent efforts on expediting the new assemblies. Here, report release greatest annual number newly annotated genomes history...
Ensembl (https://www.ensembl.org) has produced high-quality genomic resources for vertebrates and model organisms more than twenty years. During that time, our resources, services tools have continually evolved in line with both the publicly available genome data downstream research applications utilise platform. In recent years we witnessed a dramatic shift landscape. There been large increase number of reference genomes through global biodiversity initiatives. parallel, there major...
Abstract Ensembl Genomes (https://www.ensemblgenomes.org) provides access to non-vertebrate genomes and analysis complementing vertebrate resources developed by the project (https://www.ensembl.org). The two collectively present genome annotation through a consistent set of interfaces spanning tree life presenting sequence, annotation, variation, transcriptomic data comparative analysis. Here, we our largest increase in plant, metazoan fungal since project's inception creating one world's...
Abstract Ensembl (https://www.ensembl.org) is a freely available genomic resource that has produced high-quality annotations, tools, and services for vertebrates model organisms more than two decades. In recent years, there been dramatic shift in the landscape, with large increase number phylogenetic breadth of reference genomes, alongside major advances pan-genome representations higher species. order to support these efforts accelerate downstream research, continues focus on scaling rapid...
Ensembl (www.ensembl.org) is an open platform integrating publicly available genomics data across the tree of life with a focus on eukaryotic species related to human health, agriculture and biodiversity. This year has seen continued expansion in number represented, >4800 >31 300 prokaryotic genomes available. The new site, currently beta, develop, holding >2700 genome assemblies. site provides genome, gene, transcript, homology variation views, will replace current Rapid Release site; this...
The Ensembl Variant Effect Predictor (VEP) is a freely available, open-source tool for the annotation and filtering of genomic variants. It predicts variant molecular consequences using Ensembl/GENCODE or RefSeq gene sets. also reports phenotype associations from databases such as ClinVar, allele frequencies studies including gnomAD, predictions deleteriousness tools Sorting Intolerant From Tolerant Combined Annotation Dependent Depletion. VEP includes options to customize prioritization....
Ensembl creates and imports genome annotations, including data on genes, variations, regulation, comparative genomics, for vertebrates, non-vertebrates, key model organisms, providing this information freely online. This webinar will provide an introduction to the new browser platform demonstrate how navigate website retrieve genomic data. The is also home all that would previously have been shared Rapid Release site. highlight improvements in these enhancements can significantly aid...
Climate change is the most debated issue of time-posing hazardous impacts on life earth. Like other living entities, insects are also influenced by rising temperatures, elevated carbon dioxide (CO2) and fluctuating precipitating patterns as range expansion, increased epizootics (insect outbreaks) new species introduction in regions where previously these were not reported. Increasing temperature CO2 have substantial plant–insect interaction integrated pest management programmes. Rising...
Refined foods are commonly depleted in certain bioactive components that abundant ‘natural’ (plant) foods. Identification and addition of these ‘missing’ bioactives the diet is, therefore, necessary to counteract deleterious impact convenience food. In this study, multiomics approaches were employed assess popular supplementary soluble dietary fibers inulin psyllium, both isolation combination with a refined animal feed. A 16S rRNA sequencing 1H NMR metabolomic investigation revealed that,...
Pregnancy is associated with profound maternal metabolic changes, necessary for the growth and development of fetus, mediated by reproductive signals acting on organs. However, role brown adipose tissue (BAT) in regulating gestational metabolism unknown. We show that BAT phenotype lost murine pregnancy, while there a gain white (WAT)-like features. This characterised reduced thermogenic capacity mitochondrial content, accompanied increased levels markers WAT lipid accumulation. Surgical...
The Ensembl Variant Effect Predictor (VEP) is a freely available, open source tool for the annotation and filtering of genomic variants. It predicts variant molecular consequence using Ensembl/GENCODE or RefSeq gene sets. also reports phenotype associations from databases such as ClinVar, allele frequencies studies including gnomAD, predictions deleteriousness tools SIFT CADD. VEP includes options to customise prioritisation. well supported updated roughly quarterly incorporate latest gene,...
Background: COPD (Chronic obstructive pulmonary disease) is a chronic inflammatory disease that causes obstructed airflow from the lungs. Many studies have been done to investigate association of between smokers and non-smokers. Most showed are more prone COPD; much comorbidity also associated with such as hypertension, Diabetes etc. Objectives: To determine frequency in terms percentage among non-smokers, observed prevalence comorbidities COPD, evaluate general characteristics selected...