A5100751809- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and Carotid Artery Diseases
- Radiomics and Machine Learning in Medical Imaging
- Acute Ischemic Stroke Management
- Neurosurgical Procedures and Complications
- Spine and Intervertebral Disc Pathology
- Lung Cancer Diagnosis and Treatment
- Proteins in Food Systems
- Neurological Disorders and Treatments
- Polysaccharides Composition and Applications
- Polysaccharides and Plant Cell Walls
- Coronary Artery Anomalies
- Chronic Kidney Disease and Diabetes
- Helicobacter pylori-related gastroenterology studies
- Vitamin D Research Studies
- Kawasaki Disease and Coronary Complications
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Issues in Pregnancy
- Cardiac Arrhythmias and Treatments
- Advanced X-ray and CT Imaging
- Functional Brain Connectivity Studies
- Neurological disorders and treatments
- Lung Cancer Treatments and Mutations
Wenzhou Medical University
2015-2024
First Affiliated Hospital of Wenzhou Medical University
2015-2024
Shangqiu Normal University
2024
Chinese Center For Disease Control and Prevention
2023
Harbin Medical University
2023
Tianjin Nankai Hospital
2018-2022
Renji Hospital
2022
Shanghai Jiao Tong University
2022
Robert Morris University
2022
Shenzhen Second People's Hospital
2022
Abstract BACKGROUND Despite advances in the treatment of poor-grade aneurysmal subarachnoid hemorrhage (aSAH), predicting long-term outcome aSAH remains challenging, although essential. OBJECTIVE To predict outcomes after using decision tree modeling. METHODS This was a retrospective analysis prospective multicenter observational registry patients with World Federation Neurosurgical Societies (WFNS) grade IV or V. Outcome assessed by modified Rankin Scale (mRS) at 12 mo, and an unfavorable...
Ultrasound induced cavitation has been explored as a method of dissolving intravascular and microvascular thrombi in acute myocardial infarction. The purpose this study was to determine the type required for success, whether longer pulse duration therapeutic impulses (sustaining cavitation) could restore both epicardial flow with technique. Accordingly, 36 hyperlipidemic atherosclerotic pigs, thrombotic occlusions were mid-left anterior descending artery. Pigs then randomized either a) ½...
Abstract Objectives Construct and validate a nomogram model integrating the radiomics features clinical risk factors to differentiating axial spondyloarthritis (axSpA) in low back pain patients undergone sacroiliac joint (SIJ)-MRI. Methods A total of 638 confirmed as axSpA (n = 424) or non-axSpA 214) who were randomly divided into training 447) validation cohorts 191). Optimal signatures constructed from 3.0 T SIJ-MRI using maximum relevance–minimum redundancy (mRMR) least absolute shrinkage...
β-Secretase, the β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1), is a key hydrolytic in pathway of β-amyloid (Aβ) production brain patient with Alzheimer's disease (AD). BACE1 considered promising biomarker for early detection AD. A ferrocene probe (Fc-Probe) synthesized, where aldehyde group on can specifically recognize N terminus APP peptide fragment. The sensor's design involves gold nanoparticles (AuNPs) glassy carbon electrode (GCE) surface, which allows binding When...
Hypertension is a common comorbidity in patients with unruptured intracranial aneurysms and closely associated the rupture of aneurysms. However, only few studies have focused on risk comorbid hypertension. This retrospective study aimed to construct prediction models for middle cerebral artery (MCA) aneurysm hypertension using machine learning (ML) algorithms, constructed were externally validated multicenter datasets.We included 322 MCA who being treated four hospitals. All participants...
Background: Several studies have investigated the role of off-label non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation (AF). We aimed to compare effectiveness and safety outcomes between underdose or overdose vs. on-label dose NOACs AF patients. Methods: The PubMed database was systematically searched until August 2021. Observational cohorts were included if they compared risk ratios (RRs) 95% confidence intervals (CIs) pooled using a fixed-effects...
Abstract Background: The coronavirus disease-19 (COVID-19) is a highly infectious disease. Moreover, 14% of the discharged patients tested virus positive again. However, underlying clinical mechanisms are still under investigation. Case presentation: current study summarized course, radiological features and laboratory test results two COVID-19 who again during quarantine after hospital discharge. We found that while all symptoms were relieved, their lesions in lungs not fully recovered,...
Objective Small intracranial aneurysms are increasingly being detected; however, a prediction model for their rupture is rare. Random forest modeling was used to predict the status of small middle cerebral artery (MCA) with morphological features. Methods From January 2009 June 2020, we retrospectively reviewed patients MCA (<7 mm). The were randomly split into training (70%) and internal validation (30%) cohorts. Additional independent datasets external 78 from another four...
Background/Objective: Hematoma expansion (HE) predicts poor outcome and is an appealing treatment target in spontaneous intracerebral hemorrhage (ICH). Clinical evidence has shown association of HE with peripheral white blood cells (WBC) count, but the individual contributions leukocyte subtypes between literatures are described inconsistently. Our aim was to determine relationship admission absolute differential counts by using different growth definitions. Methods: We analyzed ICH patients...
Background Aneurysmal subarachnoid haemorrhage (SAH) is a devastating disease. Anterior communicating artery (ACoA) aneurysm the most frequent location of intracranial aneurysms. The purpose this study was to predict clinical outcome at discharge after rupture ACoA using random forest machine learning technique. Methods A total 607 patients with ruptured aneurysms were included in between December 2007 and January 2016. In addition basic variables, 12 morphologic parameters evaluated....
Stage I lung adenocarcinoma is a heterogeneous group. Previous studies have shown the prognostic evaluation value of PET/CT in this cohort; however, few focused on stage invasive manifesting as solid nodules. This study aimed to evaluate recurrence risk for patients with nodules based 18F-FDG PET/CT, CT imaging signs, and clinicopathological parameters.We retrospectively enrolled 230 who underwent examination between January 2013 July 2019. Metabolic parameters: maximum standard uptake...
To evaluate the reliability and validity of Patient Health Questionnaire-9 (PHQ-9) in patients with acne. Three hundred acne were enrolled from January 2019 to December 2019. PHQ-9 Hamilton Depression Scale(HAMD) survey was conducted their depression status. Cronbach's α coefficient test-retest after 1 week used analyze PHQ-9. Factor analysis, Spearman correlation receiver operating characteristic curve (ROC curve) for analysis PHQ-9.The screening analyzed different subgroups. Two...
Background and Purpose: We aimed to compare blend sign (BS) with other noncontrast computed tomography (NCCT) markers predict the extent of hematoma expansion (EHE) in patients spontaneous intracerebral hemorrhage (sICH). Methods: Patients sICH who admitted our Neurology Emergency Department from September 2013 January 2019 were enrolled. The EHE was calculated as absolute increase volume between baseline follow-up CT (within 72 h). also categorized into 4 groups: "no growth"; "minimal...
Study Design: Descriptive retrospective study. Objective: DDH is a common lower limb deformity. It has been reported that this deformity can change the sagittal alignment of spine and pelvis. Sacral obliquity (SO) iliac (IO) have proven simple reliable pelvic-lower coronal parameters to evaluate balance To study spine-pelvic compensation mechanism pelvic in patients with developmental dysplasia hip (DDH). Methods: We collected data 110 our hospital from January 2009 December 2019, who...