- Characterization and Applications of Magnetic Nanoparticles
- Geomagnetism and Paleomagnetism Studies
- Microfluidic and Bio-sensing Technologies
- Acoustic Wave Resonator Technologies
- Particle accelerators and beam dynamics
- Advanced MEMS and NEMS Technologies
- Electrical and Bioimpedance Tomography
- Advanced MRI Techniques and Applications
- Electric Motor Design and Analysis
- Magnetic Field Sensors Techniques
- Magnetic Properties and Applications
Universität Hamburg
2020-2024
University Medical Center Hamburg-Eppendorf
2020-2024
Hamburg University of Technology
2020-2024
Abstract Since the initial patent in 2001, Magnetic Particle Imaging community has endeavored to develop a human-applicable scanner, incorporating contributions from various research fields. Here we present an improved head-sized scanner with low power consumption, operated by open-source software and characterize it emphasis on human safety. The focus is evaluation of technical components phantom experiments for brain perfusion. We achieved 3D single- multi-contrast imaging at 4 Hz frame...
Magnetic Particle Imaging (MPI) is a novel and versatile imaging modality developing towards human application. When up-scaling to size, the sensitivity of systems naturally drops as coil depends on bore diameter. Thus, new methods push limit further have be investigated cope for this loss. In paper dedicated surface mice developed, improving in cerebral applications. Similar MRI developed improves due closer vicinity region interest. With presented work, it possible image tracer samples...
Magnetic nanoparticles are a valuable tool in many biomedical applications and can be used for diagnostic therapeutic purposes. In magnetic particle imaging (MPI) spectroscopy (MPS), the particles subjected to dynamic field magnetization response is simultaneously measured using one or multiple receive coils. Separating signal from feed-through commonly done by advanced passive filtering, which distorts signal. To correct this distortion, transfer function of chain needs known. While...
Magnetic field generators are a key component of Particle Imaging (MPI) systems, and their power consumption is major obstacle on the path to human‐sized scanners. Despite importance, focused discussion these rare, comprehensive description design process currently lacking. This work presents methodology for optimization selection operating with soft magnetic materials outside linear regime in context MPI. Key elements mathematical model generators, formalism defining sequences, relationship...
Abstract Determining the position and orientation of a medical instrument is essential for accurate procedures in endoscopy, surgery, vascular interventions. Recently, novel sensor based on torsional pendulum-like magneto-mechanical motion has been proposed. This passive, wireless inductively coupled to transmit-receive coil array. setup allows determination all 6 degrees freedom using characteristic resonance sensor. Additional physical quantities such as temperature pressure can be...
Since the initial patent in 2001, Magnetic Particle Imaging (MPI) community has been striving to develop an MPI scanner suitable for human applications. Numerous contributions from different research fields, regarding tracer development, reconstruction methods, hardware engineering, and sequence design have employed pursuit of this objective. In work, we introduce thoroughly characterize improved head-sized with emphasis on safety. The is operated by open-source software that enables...