A5054198905- Fibromyalgia and Chronic Fatigue Syndrome Research
- Rheumatoid Arthritis Research and Therapies
- Osteoarthritis Treatment and Mechanisms
- Bone health and osteoporosis research
- Systemic Lupus Erythematosus Research
- Inflammatory mediators and NSAID effects
- Spondyloarthritis Studies and Treatments
- Gout, Hyperuricemia, Uric Acid
- Human Health and Disease
- Vitamin D Research Studies
- Global Health Care Issues
- Autoimmune and Inflammatory Disorders Research
- Occupational Health and Performance
- Global Public Health Policies and Epidemiology
- Health and Wellbeing Research
- Quantum Computing Algorithms and Architecture
- Physical Education and Training Studies
- Vasculitis and related conditions
- Bone Metabolism and Diseases
- Global Maternal and Child Health
- Musculoskeletal synovial abnormalities and treatments
- Climate Change and Health Impacts
- Bone health and treatments
- Alkaline Phosphatase Research Studies
- Pharmacological Effects of Natural Compounds
Era's Lucknow Medical College and Hospital
2021-2025
Methodist Hospital
2024
Deutsche Telekom (Germany)
2024
Houston Methodist
2024
Centurion University of Technology and Management
2024
Indian Institute of Information Technology Design and Manufacturing Jabalpur
2022-2023
Visvesvaraya National Institute of Technology
2022
Georgia Institute of Technology
2022
King George's Medical University
2008-2021
University of North Texas
2021
18% of the world's population lives in India, and many states India have populations similar to those large countries. Action effectively improve health requires availability reliable comprehensive state-level estimates disease burden risk factors over time. Such not been available so far for all major diseases factors. Thus, we aimed estimate every state as part Global Burden Disease (GBD) Study 2016.Using data sources, State-Level Initiative estimated (metrics were deaths,...
Infection with hepatitis E virus (HEV) is a major cause of acute viral in several developing countries. Although usually self-limiting and benign, the disease particularly severe among pregnant women, mortality rates reaching 15-20%.Immune parameters women (P-HEV) were investigated compared those non-pregnant patients (N-HEV), healthy (PC) (NPC) women.Peripheral blood mononuclear cells (PBMC) from P-HEV had lower lymphocyte proliferation response to phytohemagglutinin (PHA) than PC NPC...
Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology and mainly characterized by the progressive erosion cartilage leading to chronic polyarthritis joint distortion. Although exact pathogenesis has yet not been elucidated, however, studies suggest that cellular proliferation synoviocytes result in pannus formation which damages bone. Recent reports also support role free radicals its pathogenesis. Apart from conventional treatment strategies using nonsteroidal...
Abstract Background/Purpose To compare the performance of Disease Assessment Score 28 joints – C‐reactive protein ( DAS ‐28‐ CRP ), Clinical Activity Index CDAI ) and Simplified SDAI composite measures to assess status patients with rheumatoid arthritis RA on methotrexate, versus ‐28 as gold standard. Methods One hundred thirty‐five per 2010 American College Rheumatology/European League Against Rheumatism criteria were included in prospective study. The disease activity was assessed at...
<h3>Objective</h3> To determine whether serial ANA testing predicts biological disease modifying antirheumatic drugs (bDMARD)-associated ANA/dsDNA production in patients with rheumatoid arthritis (RA). <h3>Methods</h3> Serial autoantibody profiles, bDMARD treatment sequences and clinical data were collected from identified our database that since 2005 received (i) a first (tumour necrosis factor inhibitor (TNFi)) (ii) tocilizumab and/or abatacept. <h3>Results</h3> Of over 1000 patients, 454...
Objectives Patients with fibromyalgia syndrome (FMS) often experience problems such as poor quality of life (QoL), loss self-efficacy (SE), inappropriate coping behavior, and chronic widespread pain along other symptoms. Recent studies have indicated that sense SE effective strategies (CSs) are the crux on which management enrichment QoL FMS patients depend. Realizing importance this subject for rehabilitation people FMS, study aimed at analyzing correlation between severity QoL, SE, CSs...
In the present study we examined involvement of oxidative and antioxidative parameters in women with fibromyalgia syndrome (FMS) also evaluated their correlation Fibromyalgia Impact Questionnaire Revised (FIQR).Oxidative stress was determined by measuring levels lipid peroxides (LPO) protein carbonyls plasma like catalase, glutathione peroxidase (GPx) reductase (GR) blood lysate 30 female patients satisfying American College Rheumatology (ACR) criteria for FMS healthy females without FMS....
Abstract Objective To determine if colchicine added to nimesulide may have a beneficial effect on osteoarthritis (OA) of the knee. Methods Colchicine 0.5 mg twice daily or placebo was (a nonsteroidal antiinflammatory drug) in 36 patients with OA knee randomized, double‐blind, placebo‐controlled trial over 5‐month period. Results The 30% improvement rate at 20 weeks higher group than control receiving placebo, as measured by total Western Ontario and McMaster University Osteoarthritis scores...
Abstract Objective To investigate whether methotrexate ( MTX ) administered orally to rheumatoid arthritis RA patients in split doses at 2–3 days’ interval, would result equal or better efficacy, tolerability and compliance, without increasing toxicity compared single weekly dose given parenterally. Materials methods One hundred thirty‐five fulfilling the American College of Rheumatology ACR 2010 criteria for , on 7.5 mg orally, with Simplified Disease Activity Index SDAI > 11 were...
Tuberculin skin test has been used as an indicator of latent tuberculosis in patients with Rheumatoid Arthritis (RA) before administration biologicals. Effect Disease modifying antirheumatic drugs (DMARDs) and steroids on the result tuberculin (TST) may have important implications interpretation results this test. Objectives. To find prevalence positive TST rheumatoid effect standard treatment TST. Method. In cross-sectional study two hundred fifty RA above 18 years age, classified using...
Fibromyalgia syndrome (FMS) is characterized by altered pain perception with chronic, widespread musculoskeletal pain. The relationship between nitric oxide, oxidative stress and the severity of FMS has not been studied. This study evaluated NO levels in plasma, LPO products antioxidants Red Cell lysate patients correlated it disease severity.105 who fulfilled 1990 ACR Criteria 105 age- sex-matched healthy controls were recruited over two years from 2013 to 2015. Antioxidative enzyme...
Abstract Objective To compare ultrasound‐detected abnormalities, namely double contour sign ( DCS ) and hyperechoic aggregates HAG s), at two sites (knee first metatarsophalangeal [1st MTP ] joints) versus six joint, 1st radiocarpal talar patellar tendon triceps tendon) in gout patients. Methods Forty‐seven clinically diagnosed patients 50 subjects (serum uric acid < 7 mg/dL) as controls were included. was looked for three articular cartilage (first metatarsal, tibiotalar femoral...
To determine sexual dysfunctions and urinary symptoms in male ankylosing spondylitis (AS) patients their association with various disease patient factors.In this prospective case control study conducted at a tertiary care teaching institution, 100 males AS were compared to controls using International Index of Erectile Function-15 (IIEF), Prostate Symptom Score (IPSS), Hospital Anxiety Depression Scale (HADS) global question for overall relationship partners. Bath Functional (BASFI), visual...
Objective: Hydroxychloroquine (HCQ) has been used for a long time worldwide as therapy rheumatoid arthritis (RA). This trial was designed to determine whether HCQ efficacious and safe in Indian patients with RA.Research design methods: The multicentre, placebo controlled, randomized double-blind study. One hundred twenty-two RA were enrolled 3 different centres the (26 males 96 females age group of 18–60 years). Patients receive either hydroxychloroquine tablets (n = 61) two 200 mg daily or...