A5086432270- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Mycology
- Viral gastroenteritis research and epidemiology
- Dental Research and COVID-19
- Advanced Proteomics Techniques and Applications
- Yersinia bacterium, plague, ectoparasites research
- Microbial Inactivation Methods
- Plant and Fungal Interactions Research
- Digital Imaging for Blood Diseases
- Enterobacteriaceae and Cronobacter Research
- Gut microbiota and health
- Humic Substances and Bio-Organic Studies
- Microfluidic and Bio-sensing Technologies
- Electromagnetic Fields and Biological Effects
- Clostridium difficile and Clostridium perfringens research
- Infection Control and Ventilation
- Bacteriophages and microbial interactions
University of Ghana
2015-2024
Noguchi Memorial Institute for Medical Research
2015-2024
Cardiff University
2016-2023
Efforts to control the spread of Buruli ulcer – an emerging ulcerative skin infection caused by Mycobacterium ulcerans - have been hampered our poor understanding reservoirs and transmission. To help address this issue, we compared whole genomes from 18 clinical M. isolates a 30km2 region within Asante Akim North District, Ashanti region, Ghana, with 15 other elsewhere in Ghana surrounding countries Ivory Coast, Togo, Benin Nigeria. Contrary expectations finding minor DNA sequence variations...
Identifying the source reservoirs of Mycobacterium ulcerans is key to understanding mode transmission this pathogen and controlling spread Buruli ulcer (BU). In Australia, native possum can harbor M. in its gastrointestinal tract shed high concentrations bacteria feces. To date, an analogous animal reservoir Africa has not been identified. Here we tested hypothesis that common domestic animals BU endemic villages Ghana are species Australian possum. Using linear-transects at 10-meter...
Viruses represent a major threat to human health and are capable of spreading either via direct exposure or contamination inanimate surfaces. Certain viruses have been shown remain viable on surfaces dental implants devices, fabrics plastics for hours, days weeks representing source continuous viral transmission which must be mitigated. In this study, we compared the effect varying concentrations gaseous ozone (40, 20, 10, 5, 1 ppm) Herpes Simplex Virus (HSV-1) coated clear polystyrene...
Microwaves are a form of non-ionizing radiation composed electric (E) and magnetic (H) fields absorbed by biological tissues with high water content. Our study investigated the effect E field, H combination both (E + H) field’s exposure structurally diverse micro-organisms, at frequency 2.45 GHz. We observed that to microwave field an amplitude 9.3 kV/m had no significant on cell viability; however, it did increase membrane permeability Mycobacterium smegmatis propidium iodide range...
INTRODUCTION Buruli ulcer caused by Mycobacterium ulcerans is a devastating necrotic skin disease. PCR, recommended for confirmation of WHO, requires an adequately equipped laboratory, often delaying diagnosis and treatment patients in remote or humanitarian settings. We aimed to assess loop- mediated isothermal amplification (LAMP), which molecular assay DNA suggested timely low-resource METHODS This study combines quantitative qualitative methods. First, we evaluated simple rapid syringe...
Clostridium difficile is a major cause of hospital acquired infection that poses significant diagnostic challenges. In this paper, new type resonant microwave applicator proposed for the liberation DNA from C. spores via disruption, followed by rapid detection using sandwich hybridization assay. A split-ring resonator designed to operate at 2.4 GHz with 3 mm active gap region contains an isolate volume approximately 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML"...