A5100526593- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Glaucoma and retinal disorders
- Healthcare and Venom Research
- Endoplasmic Reticulum Stress and Disease
- CRISPR and Genetic Engineering
- Cellular transport and secretion
- Acupuncture Treatment Research Studies
- Corporate Finance and Governance
- Traumatic Brain Injury and Neurovascular Disturbances
- Plant and Fungal Interactions Research
- Cassava research and cyanide
- Zebrafish Biomedical Research Applications
- Plant Micronutrient Interactions and Effects
- Protist diversity and phylogeny
- Medical Imaging and Analysis
- Intracerebral and Subarachnoid Hemorrhage Research
- Hearing Loss and Rehabilitation
- Pelvic floor disorders treatments
- Genetic and Kidney Cyst Diseases
- Bluetooth and Wireless Communication Technologies
- Fiscal Policies and Political Economy
- Cervical and Thoracic Myelopathy
- Single-cell and spatial transcriptomics
- Noise Effects and Management
Center for Excellence in Molecular Cell Science
2023-2024
University of Chinese Academy of Sciences
2023-2024
Wuhan University
2023-2024
Beijing Tsinghua Chang Gung Hospital
2020-2023
Tsinghua University
2015-2023
Chinese Academy of Sciences
2010-2022
Changchun Institute of Optics, Fine Mechanics and Physics
2022
Center for Life Sciences
2019-2021
Shanghai Traditional Chinese Medicine Hospital
2020
First Hospital of Jiaxing
2017-2020
Abstract Introduction – It is prerequisite and crucial to extract RNA with high quality integrity in order carry out molecular biology studies any plant species of a family. Euphorbiaceae members are known for levels their waxes, oils polysaccharides, polyphenolics secondary metabolites. These conditions recognised interfere unfavourably various methodologies isolation. Objective To develop simple, rapid reproducible cetyltrimethylamonium bromide (CTAB)‐based protocol, reduce the time cost...
With the development of communication technology, in order to meet smart city's demand for intelligent infrastructure, street lighting system based on NB-IoT is an effective method realize goal. This paper elaborates system's architecture, including perception and control layer, transport platform layer application layer. In addition, actual built verify. uses STM32 build controller, relies China Telecom's network data transmission, finally using IoT management platform-Huawei OceanConnect-...
A growing body of research recently suggested the association between vestibular dysfunction and cognitive impairment. Meniere's disease (MD), a common clinical disorder, is usually accompanied by hearing loss emotional stress, both which may mediate relationship vestibule cognition. It currently unknown whether decline in MD patients could improve through treatment how it relates to multiple characteristics, particularly severity vertigo. Therefore, present study, were followed up for 3, 6,...
In recent years, economic research has increasingly focused on the increase in local government debt, attracting attention of regulators. Using data from 2006 to 2022, this study empirically examines how debt affects financing activities. The results reveal debt' s crowding-out effect financing, particularly for non-state-owned enterprises. Further analysis reveals that negative impact is driven by 'passive crowding-out' rather than 'active choice' Local governments can directly influence...
A variety of causes may induce sudden deafness. However, it remains challenging to determine the exact cause in a clinic. There is no standard treatment for this disease due its unclear etiology.The present study aims investigate clinical efficacy intratympanic injection dexamethasone treating deafness.A total 154 patients with deafness were retrospectively analyzed. The evaluation was based on AAO-HNS evaluative criteria. All initially treated within seven days by an intravenous drip...
with the development of industrial 4.0, higher accuracy is required for optical linear encoder which serves as an important type displacement sensor. The mounting error a great impediment to this quest, especially exposed-type encoders. This paper presents novel approach based on theory multi-slit diffraction increase tolerance. A model amplitude-phase grating designed and simulated MATLAB Virtual Lab Fusion. result shows that sample functional when gap between reading head reflective tape...
Background: Endolymphatic sac decompression surgery (ESDS) is commonly used for intractable Meniere’s disease, but its effect remains controversial because of the low rate vertigo control.Objectives: In present study, we examined ESDS combined with posterior tympanotomy local steroids as a new therapeutic strategy disease.Materials and methods: This retrospective study enrolled 19 patients disease using between 2015 2018. Postoperatively recorded evaluated changes in attack frequency hearing...
This study aimed to analyze the abnormal rates of immune related factors in serum sudden deafness (SD) patients, and discuss correlation between these indicators degree pathological changes SD patients.From March 2018 January 2021, 90 patients with who were hospitalized Beijing Tsinghua Changgeng Hospital enrolled as participants, 60 healthy examinees served control group. Antinuclear antibody (ANA), anticardiolipin immunoglobulin G (ACA-IgG), M (ACA-IgM), anti-β-glucoprotein (anti-β-GP)...
Maintaining chromosome euploidy in zebrafish embryonic cells is challenging because of the degradation genomic integrity during cell passaging. In this study, we report derivation lines from single blastomeres. These have a stable status attributed to BMP4 and exhibit continuous proliferation vitro. Twenty are successfully established Single-cell transcriptome sequencing analysis confirms fidelity gene expression profiles throughout long-term culturing at least 45 passages. The cultured...
Sudden sensorineural hearing loss (SSNHL) is a prevalent emergency in ear, nose, and throat practice. Previous studies have demonstrated that intratympanic steroid therapy (IST) can serve as salvage treatment for SSNHL after the failure of systemic (SST). This study aimed to analyze efficacy modified IST involving insertion tympanic tube gelfoam patients with SSNHL, explore its associated factors. Totally, 74 who were aged 22–81 years enrolled allocated either control group (n = 25) or 49)...
Age-related hearing loss (ARHL) may limit communication, which is closely associated with cognitive decline of the elderly and negatively affects their quality life. In ARHL patients who suffer chronic otitis media (COM), impairment worsen affect cognition It currently unknown whether restoration conductive in mixed through middle ear surgeries can improve both function life patients. Therefore, present study, were followed up for 6 months after COM, functions assessed using Montreal...
As an important root crop, cassava ( Manihot esculenta Crantz) is not only vital to food security in tropics and subtropics but also the predominant raw material of starch industry. Ensuring a high stable yield with better quality always main objective breeders. Nowadays, breeding faces transition phase from traditional cross-breeding genetic engineering. Therefore, it essential understand specific economic traits biological features order effectively improve crop through application...
Cilia are organelles for cellular signaling and motility. They assembled in G0/G1 disassembled prior to mitosis. Compared what is known about ciliary assembly, less understood disassembly. To uncover new mechanisms of disassembly, we performed an unbiased chemical screen. Chlamydomonas reinhardtii cells were experimentally induced disassembly by treatment with sodium pyrophosphate. An FDA approved drug library (HY-L022P-1, MedChemExpress) was used the screening. Primary screening further...
Abstract Regulated ER-to-Golgi trafficking is a fundamental cellular process that enables ER-resident transcription factors to sense perturbations in the ER environment and activates transcriptional programs restore homeostasis. Current models suggest sensor activation initiated by dissociation from its binding partners. Here we challenge this model demonstrating unfolded protein ATF6 sorted Golgi as newly synthesized peripheral membrane beyond reach of retainer, translocon inhibition alone...
In emerging market countries with an imperfect direct financial system, the issuance of government debt may impact corporate financing. This paper, based on a sample Chinese listed corporations from 2006 to 2018, finds that reduces amount financing and increases finance cost. Regarding influencing mechanism, commercial bank loans are primary source funds for various entities, local governments compete in ordinary by issuing through platforms. Due comparative advantage, banks hold more debt....
Objective To explore the effect of pour ‘T' fixed method on subarachnoid hemorrhage treatment lumbar cistern.Methods Totals 120 cases with cistern drainage were randomly divided into observation group( n =60) and control group(n =60),and group adopted to fix tube while ‘ —' fixe tube.Tape roll edge or shift,tube falling off number,pressure,impeded drainage,tape allergic two groups observed compared.Results The incidence tape shift during 48 h after h,the pressure occurred...
Objective To observe the clinical efficacy of traditional Chinese medicine(TCM) directing therapy in treatment pelvic inflammatory disease sequelae (SPID) with syndrome Qi stagnation and blood stasis. Methods From April 2016 to 2018, 60 patients SPID stasis Traditional Medicine Hospital Pudong New Area Shanghai were randomly divided into group control according digital table, 30 cases each group.The was treated FukeQianjin capsules, TCM therapy, a course 1 month.The observed, score...