A5102882818- 3D Printing in Biomedical Research
- Neuroscience and Neural Engineering
- Advanced Combustion Engine Technologies
- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Nerve injury and regeneration
- Additive Manufacturing and 3D Printing Technologies
- Engineering Applied Research
- Vehicle emissions and performance
- Internet of Things and Social Network Interactions
- Tissue Engineering and Regenerative Medicine
- Anatomy and Medical Technology
- Graphene and Nanomaterials Applications
- Advanced Materials and Mechanics
- Combustion and flame dynamics
- IPv6, Mobility, Handover, Networks, Security
- Caching and Content Delivery
- Advanced Sensor and Energy Harvesting Materials
- IoT and Edge/Fog Computing
- Vehicular Ad Hoc Networks (VANETs)
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Military Defense Systems Analysis
- Service-Oriented Architecture and Web Services
University of Ulsan
2011-2023
George Washington University
2015-2021
Sungkyunkwan University
2015-2018
Keio University
2014-2018
Korea Electronics Technology Institute
2017
William & Mary
2012
Ulsan University Hospital
2012
Four dimensional (4D) printing is an emerging technology with great capacity for fabricating complex, stimuli-responsive 3D structures, providing potential tissue and organ engineering applications. Although the 4D concept was first highlighted in 2013, extensive research has rapidly developed, along more-in-depth understanding assertions regarding definition of 4D. In this review, we begin by establishing criteria printing, followed summary state-of-the-art technological advances field....
Nanomaterials, such as carbon nanotubes (CNTs), have been introduced to modify the surface properties of scaffolds, thus enhancing interaction between neural cells and biomaterials. In addition superior electrical conductivity, CNTs can provide nanoscale structures similar those present in natural environment. The primary objective this study is investigate proliferative capability differential potential stem (NSCs) seeded on a CNT incorporated scaffold.Amine functionalized multi-walled...
4D printing represents one of the most advanced fabrication techniques for prospective applications in tissue engineering, biomedical devices, and soft robotics, among others. In this study, a novel multiresponsive architecture is developed through stereolithography-based printing, where universal concept stress-induced shape transformation applied to achieve reprogramming. The light-induced graded internal stress followed by subsequent solvent-induced relaxation, driving an autonomous...
A 4D cardiac patch with physiological adaptability may improve iPSC cell therapy for the treatment of myocardial infarction.
Three-dimensional (3D) bioprinting is a rapidly emerging technique in the field of tissue engineering to fabricate extremely intricate and complex biomimetic scaffolds range micrometers. Such customized 3D printed constructs can be used for regeneration tissues such as cartilage, vessels, nerves. However, printing techniques often offer limited control over resolution compromised mechanical properties due short selection printable inks. To address these limitations, we combined...
Three-dimensional (3D) functional constructs with biomimetic mechanical and chemical properties are ideal for various regenerative medicine applications. These of 3D fabricated mainly depend on the intrinsic characteristics materials fabrication method. In this respect, current use hydrogels musculoskeletal tissue repair is not due to lack suitable properties, as well high requirement success. To overcome limitation, we developed a novel functionalized hydrogel bioactive gold nanoparticles...
Central nerve repair and regeneration remain challenging problems worldwide, largely because of the extremely weak inherent regenerative capacity accompanying fibrosis native nerves. Inadequate solutions to unmet needs for clinical therapeutics encourage development novel strategies promote regeneration. Recently, 3D bioprinting techniques, as one a set valuable tissue engineering technologies, have shown great promise toward fabricating complex customizable artificial scaffolds. Gelatin...
4D printing is a highly innovative additive manufacturing process for fabricating smart structures with the ability to transform over time. Significantly different from regular techniques, this study focuses on creating novel hierarchical micropatterns using unique photolithographic-stereolithographic-tandem strategy (PSTS) soybean oil epoxidized acrylate (SOEA) inks effectively regulating human bone marrow mesenchymal stem cell (hMSC) cardiomyogenic behaviors. The effect refers autonomous...
Abstract Nano-based drug delivery devices allowing for effective and sustained targeted of therapeutic agents to solid tumors have revolutionized cancer treatment. As an emerging biomedical technique, cold atmospheric plasma (CAP), ionized non-thermal gas mixture composed various reactive oxygen species, nitrogen species UV photons, shows great potential Here we seek develop a new dual method by integrating promising CAP novel loaded core-shell nanoparticles evaluate its underlying mechanism...
Abstract Current therapies for nerve regeneration within injured tissues have had limited success due to complicated neural anatomy and inhibitory barriers in situ. Recent advancements 3D bioprinting technologies enabled researchers develop novel scaffolds with complex architectures an effort mitigate the challenges that beset reliable defined tissue regeneration. Among several possible neuroregenerative treatment approaches are being explored today, bioprinted unique advantage of highly...
A traumatic injury of peripheral nerves is serious clinical problem that may lead to major loss nerve function, affecting quality patient's life. Currently, autograft widely used reconstruct the gap. However, such surgical procedure suffers from many disadvantages including donor site morbidity and limited availability. In order address these issues, neural tissue engineering has focused on development synthetic scaffolds support bridging a larger gap improving generation. For this purpose,...
As the most versatile and promising cell source, stem cells have been studied in regenerative medicine for two decades. Currently available culturing techniques utilize a 2D or 3D microenvironment supporting growth proliferation of cells. However, these culture systems fail to fully reflect supportive biological environment which reside vivo, contain dynamic biophysical cues. Herein, 4D programmable substrate with self-morphing capability is presented as means enhance induce differentiation...
Although the process by which cortical tissues of brain fold has been subject considerable study and debate over past few decades, a single mechanistic description phenomenon yet to be fully accepted. Rather, two competing explanations folding have arisen in recent years; known as axonal tension differential tangential expansion models. In present review, these models are introduced analyzing computational, theoretical, materials-based, cell studies yielded them. Then Four-dimensional...
Abstract The effects of low intensity pulsed ultrasound (LIPUS) on proliferation and chondrogenic differentiation human mesenchymal stem cells (hMSCs) seeded 3D printed poly‐(ethylene glycol)‐diacrylate (PEG‐DA) scaffolds with varying pore geometries (square hexagonal channels) were investigated. scaffold square pores resulted in higher hMSC growth than a solid or hexagonally porous scaffold. optimal LIPUS parameters at 1.5 MHz found to be 100 mW/cm 2 20% duty cycle. stimulation increased by...
Like the morphology of native tissue fiber arrangement (such as skeletal muscle), unidirectional anisotropic scaffolds are highly desired a means to guide cell behavior in engineering. In contrast, contour-like staircases exhibit directional topographical cues and judged an inevitable defect fused deposition modeling (FDM). this study, we will translate staircase into effective bioengineering strategy by integrating FDM with surface coating technique (FCT) investigate effect on regulating...
Adipose-derived stem cells (ADSCs) have the capacity to differentiate into neural precursor which can be used for nerve regeneration. However, their inherently low neurogenic differentiation efficiency limits further clinical applications. This study was designed promote efficacy of ADSCs by integrating conductive hydrogel-based microwells with electrical stimulation (ES). We hypothesize that will more efficiently when electrically stimulated in hydrogel microwells. To make microwell,...