In this nationwide study, we investigate the risk and severity of all road traffic accidents in patients with obstructive sleep apnea (OSA).We used unique Danish registries to identify citizens receiving a diagnosis OSA between 1995 2015. As reference cohort, randomly selected 10 sex- age-matched for each patient. We Poisson regression calculate incidens rate ratio (IRR) (motor vehicle, bicycle, pedestrian) both groups, Cox proportional analysis compare first motor vehicle accident. Lastly,...

To study if minimally invasive repair of pectus excavatum (PE) in adult patients would improve cardiopulmonary function at rest and during exercise as we have found previously young adolescent with PE. Nineteen (>21 year age) were studied bicycle before surgery 1 postoperatively. Lung spirometry was performed rest. Cardiac output, heart rate aerobic capacity measured using a photo-acoustic gas-rebreathing technique exercise. Data are shown mean ± standard deviation. Fifteen completed the...

Abstract Study Objectives In this nationwide study, we used the unique Danish registries to estimate risk of suicide and deliberate self-harm in patients with obstructive sleep apnea (OSA). Methods We identified all citizens receiving a diagnosis OSA between 1995 2015. As reference cohort, randomly selected 10 for each patient, matched by sex birth year. Using Fine Gray competing regression, estimated cumulative incidences suicide, Cox proportional regression analysis was compare cohort....

Development of hypoparathyroidism (hypoPT) after total thyroidectomy (TT) may increase the risk kidney-related morbidity. We aimed to examine hypoPT and chronic kidney disease (CKD) in patients undergoing TT Denmark over a 20-year period.

Objective For the first time, we wish to assess psychiatric burden in adult patients living with small, unrepaired atrial septal defects (ASD) using register-based data, combined self-reported measures on levels emotional distress and educational status. Design A descriptive study both unique Danish registries validated questionnaires scales, including: The Symptom Checklist, Whiteley-7, Brief Illness Perception Questionnaire. Patients Adult ASD, diagnosed between 1953 2011. Outcome Measures...

Objective Fontan circulations have obligatory venous hypertension, depressed cardiac output and abnormal arterial elastance. Ventriculovascular coupling is known to be abnormal, but the underlying mechanisms are poorly defined. We aim describe histopathological features of vascular remodelling encountered in central arteries veins circulation as a possible pathological representation ventriculovascular coupling. Methods Postmortemvasculature (inferior vena cava (IVC), superior (SVC),...

Objective Adult patients with small, unrepaired atrial septal defects have an increased risk of pneumonia, fibrillation, and stroke. Furthermore, they higher late mortality than the background population. The functional capacity is unknown in these patients. Therefore, our objective was to determine exercise adult diagnosed defect compared healthy controls. Design A cross-sectional study. Patients defects, aged 18-65, between 1953 2011. Interventions Cardiopulmonary test performed using...

Complications following the Nuss procedure for correction of pectus excavatum later than 30 days are rare. We report a 40-year old man who developed dyspnoea and was diagnosed with pulmonary stenosis more 2 years after undergoing procedure. This discovered to be caused by displaced bar. Following removal bars, symptoms along right ventricular outflow tract obstruction disappeared.

In recent Danish nationwide register-based study, adults with small, unrepaired atrial septal defects (ASD) have increased risk of pneumonia, fibrillation (AF) and stroke. Moreover, they revealed higher mortality than the background population. this we evaluate hidden burden ventricular arrhythmias in adult patients a ASD without previous diagnosis AF. All patients, aged 18-65, diagnosed between 1953 2011 an no documented AF were invited for 7 days Holter-recording, echocardiography 6 min...

Abstract Objective: To determine the prevalence of pacemaker and conduction disturbances in patients with atrial septal defects. Design: All an defect born before 1994 were identified Danish National Patient Registry, 297 analysed for atrioventricular block, bradycardia, right bundle branch left anterior fascicular posterior pacemaker, mortality. Our results compared pre-existing data from a healthy background population. Further, outcomes between open defects closed by surgery or...

Objective To investigate in vitro fertilisation (IVF) women with atrial septal defect (ASD), and to examine the maternal characteristics outcome of pregnancy, as well fetal infants born by ASD. Methods We used population-based registries this nationwide cohort study, including Danish individuals before 1994 who received an ASD diagnosis between 1959 2014. Patients were compared a random reference sample (ratio 10 citizens per patient) matched sex age. The Medical Birth Register (DMBR)...

A woman in her mid-80’s collapsed while home due to a sudden onset of swelling on neck compromising the airway. She was intubated on-site and brought trauma-centre where she diagnosed with an intrathyroidal bleeding compression trachea. subacute left sided thyroid lobectomy performed, giving immediate relief displaced compressed The patient discharged after 3 days. final histopathological examination revealed microfollicular adenoma extensive bleeding.

In a recent nationwide cohort study, we have discovered that patients living with an atrial septal defect (ASD) shorter life expectancy, increased risk of fibrillation, pneumonia, and psychiatric issues compared to the general population. The pathophysiological mechanisms are still unknown. objective this study is investigate if group burdened by mutations in genes associated ASD. We included 147 unrepaired curated list ASD candidate genes, were analyzed for genetic variants these using...

Background In this nationwide study, we used the unique Danish registries to estimate risk of suicide and deliberate self-harm in patients with congenital heart disease (CHD). Methods Results We identified all citizens receiving a diagnosis CHD between 1977 2007. As reference cohort, randomly selected 10 for each patient, matched by sex birth year. Using Fine Gray competing regression, estimated cumulative incidences self-harm, Cox proportional regression analysis was compare cohort. 14 433...

To explore the prevalence of synchronous and metachronous tonsillar cancer in patients with base tongue cancer, as well identifying potential risk factors linked to these secondary malignancies. We aim answer following question: Should bilateral tonsillectomy be recommended diagnosed cancer?

Abstract Objective Total thyroidectomy (TT) carries a risk of hypoparathyroidism (hypoPT). Recently, hypoPT has been associated with higher overall mortality rates. We aimed to evaluate the frequency and in patients undergoing TT Denmark covering 20 years. Design Retrospective Cohort study. Patients measurements Using population‐based registries, we identified all Danish individuals who had undergone between January 1998 December 2017. included comparison cohort by randomly selecting 10...

In this nationwide study, we used Danish population registries to estimate the excess risk of receiving permanent social security benefits for patients with obstructive sleep apnea (OSA) and track their labour force participation.We identified all citizens a diagnosis OSA between 1995 2015. As reference cohort, randomly selected 10 each patient, matched by sex birth year. Using Fine Gray competing regression, estimated cumulative incidences benefits. Cox proportional hazard models were...

Assessment of ischemic but potentially viable myocardium plays an important role in the planning coronary revascularization. Until now SPECT, PET, and MRI have been used to identify myocardium. Computed tomography (CT) is increasingly diagnose atherosclerosis.To evaluate feasibility CT enhancement as a viability marker by investigating myocardial contrast distribution over time pigs with experimentally induced antero-septal infarctions.Twelve were subjected 60 min balloon occlusion left...

This case describes the first documented clinical presentation of Sweet's syndrome with unilateral swelling neck, severe pain and fever. The radiological manifestation resembled necrotising fasciitis patient underwent acute neck dissection. was ultimately diagnosed a new subtype called syndrome, quickly recovered after treatment intravenous administration prednisolone.

Small, unrepaired atrial septal defects are considered a benign lesion with good prognosis. Recently, clinical and register-based studies discovered increased long-term mortality morbidity. The nature of these findings is not fully understood. Therefore, MRI was performed to evaluate cardiac function at rest during exercise.Adults open or spontaneously closed healthy, matched controls underwent for evaluation chamber volume. Quantitative flow scans measured blood in the ascending aorta...

Background: Assessment of ischemic but potentially viable myocardium plays an important role in the planning revascularization patients with critical coronary atherosclerosis. Traditionally, imaging modalities such as SPECT, PET, and MRI have been used for this purpose, however these methods all limitations impose logistic challenges, they are not widely clinically available. Cardiac computed tomography (CT) is being increasingly morphological functional analysis cardiovascular diseases...