To assess the validity of diagnoses atrial fibrillation (AF) and flutter (AFL) for men women recorded in Danish National Patient Registry, to relative distribution AF AFL.Review medical records incident cases and/or AFL Diet, Cancer, Health cohort study. Participants were enrolled 1993-97 with 13.6 years follow-up until 30 December, 2009.The positive predictive value combined diagnosis was 92.6% (95% CI 88.8%; 95.2%) no significant difference between sexes (men 93.7% (133/142), 90.8%...

To determine whether patients with major depressive disorder (MDD) display morphologic, functional, and metabolic brain abnormalities in limbic-cortical regions at a baseline magnetic resonance (MR) scan these changes are normalized MDD remission follow-up scan.A longitudinal 3.0-Tesla (T) imaging (MRI) study was carried out cortical thickness measurements surface-based approach, perfusion three-dimensional (3D) pseudo-continuous arterial spin labeling (pCASL), spectroscopy (1H-MRS) the...

Abstract Background Omega-3 fatty acids (n-3 FAs) may have beneficial clinical effects, and n-3 FA supplements improve outcome after surgery. Methods In a randomized double-blind placebo-controlled trial in single centre, patients referred for elective colorectal cancer surgery received either an FA-enriched oral nutritional supplement (ONS) (Supportan®, 200 ml twice daily) providing 2·0 g eicosapentaenoic acid (EPA) 1·0 docosahexaenoic (DHA) per day, or standard isocaloric isonitrogenous...

In this nationwide study, we investigate the risk and severity of all road traffic accidents in patients with obstructive sleep apnea (OSA).We used unique Danish registries to identify citizens receiving a diagnosis OSA between 1995 2015. As reference cohort, randomly selected 10 sex- age-matched for each patient. We Poisson regression calculate incidens rate ratio (IRR) (motor vehicle, bicycle, pedestrian) both groups, Cox proportional analysis compare first motor vehicle accident. Lastly,...

Journal Article A state space model for multivariate longitudinal count data Get access B Jørgensen, Jørgensen Search other works by this author on: Oxford Academic Google Scholar S Lundbye-Christensen, Lundbye-Christensen PX-K Song, Song L Sun Biometrika, Volume 86, Issue 1, March 1999, Pages 169–181, https://doi.org/10.1093/biomet/86.1.169 Published: 01 1999

PURPOSE: The study examined if preoperative plasma D-dimer level was associated with the postoperative cumulative incidence of deep venous thrombosis in patients colorectal cancer admitted for intended curative surgery. METHODS: In 176 consecutive newly-diagnosed and absence thrombosis, we measured levels performed compression ultrasonography prior to surgery, as well one week, month, year after RESULTS: up surgery 20 percent (95 confidence interval, 12 31 percent) positive group compared 5...

Omega-3 fatty acids (n-3 FA) may have beneficial clinical and immune-modulating effects in surgical patients. In a randomized, double-blind, prospective, placebo-controlled trial, 148 patients referred for elective colorectal cancer surgery received an n-3 FA-enriched oral nutritional supplement (ONS) providing 2.0 g of eicosapentaenoic acid (EPA) 1.0 docosahexaenoic (DHA) per day or standard ONS seven days before surgery. On the operation, there was significant increase production...

Previous studies have suggested a lower risk of atrial fibrillation (AF) with higher intakes fish and marine n-3 polyunsaturated fatty acids (PUFAs), but the results been inconsistent. The aim was to investigate association between consumption PUFA development AF.A total 57 053 Danish participants 50-64 years age were enrolled in Diet, Cancer, Health Cohort Study 1993 1997. Dietary intake assessed by semi-quantitative food frequency questionnaire. In total, 3345 incident cases AF occurred...

Background and Purpose— We hypothesized that total marine n-3 polyunsaturated fatty acids (PUFA), in particular eicosapentaenoic acid (EPA) docosahexaenoic (DHA) the diet adipose tissue (biomarkers of long-term intake endogenous exposure) were inversely associated with risk ischemic stroke its subtypes. Methods— The Diet, Cancer Health cohort consisted 57 053 participants aged 50 to 65 years at enrolment. All filled a food frequency questionnaire had an biopsy taken baseline. Information on...

Objective The study aimed to examine the association between socioeconomic factors (SEFs) and oral anticoagulation (OAC) therapy whether it was influenced by changing guidelines. We hypothesised that inequities in initiation of OAC reduced over time as more detailed explicit clinical guidelines were issued. Design Register-based observational study. Settings All Danish patients with an incident hospital diagnosis atrial fibrillation (AF), aged ≥30 years old high risk stroke from 1 May 1999 2...

Tissue levels of n-3 polyunsaturated fatty acids (PUFAs) have been inversely related with risk myocardial infarction (MI). Whether ratios to n-6 PUFAs, reflecting both dietary intake PUFAs and competing are better predictors future MI than PUFA fractions is unclear. We aimed at investigating whether such in adipose tissue predict fractions.Subcutaneous biopsies were obtained a random sample (n = 3,500) the Diet, Cancer Health cohort 57,053). Adipose content eicosapentaenoic acid (EPA),...

The purpose was to elucidate the association between parity and incidence of diabetes using national register data.The study population consisted all Danish women with a singleton delivery in 1982/1983 (n = 100,669), who subsequently had 74,966 deliveries. included were followed up via registries until end 2006 for subsequent deliveries, diagnosis death/emigration.A total 2021 cases (2.0%) diagnosed connection hospitalization or outpatient treatment during follow-up. Analyses adjusted fetal...

Abstract Introduction The present study investigates the association between single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 ( CHI3L1) gene and serum concentrations of YKL-40 Danish patients with rheumatoid arthritis (RA) healthy controls as well RA population. CHI3L1 is located on chromosome 1q32.1 encodes glycoprotein. are elevated compared to subjects, has been suggested be an auto-antigen may play a role development inflammation. Methods Eight SNPs promotor were genotyped...

Background: Although results from blood gas analyzers are frequently used in clinical work surprisingly few and small studies have examined reference intervals for arterial gases acid-base status. We established values based on a large group of healthy people with wide age distribution.

BackgroundThere have been discrepant findings on whether coffee consumption is associated with the rate of developing atrial fibrillation (AF).

Background. Several characteristics appear to be important for estimating the likelihood of reentering workforce after surgery. The aim present study was describe work status in a two-year time period around cardiac surgery and estimate probability returning workforce. Methods. We included 681 patients undergoing coronary artery bypass grafting and/or heart valve procedures from 2003 2007 North Denmark Region. linked hospital data DREAM database which holds information everyone receiving...

Easily accessible biomarkers for Alzheimer’s dementia (AD) are lacking and established clinical markers limited in applicability. Blood is a common biofluid biomarker discoveries, extracellular vesicles (EVs) may provide matrix exploring AD related biomarkers. Thus, we investigated proteins to neurological inflammatory processes plasma EVs. By proximity extension assay (PEA), 182 were measured EVs from patients with (n = 10), Mild Cognitive Impairment (MCI, n healthy controls 10)....