A5009720710- Pectus Deformity Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Sympathectomy and Hyperhidrosis Treatments
- Infective Endocarditis Diagnosis and Management
- Trauma Management and Diagnosis
- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Reconstructive Surgery and Microvascular Techniques
- Cardiac Structural Anomalies and Repair
- Medical Imaging Techniques and Applications
- Aortic Disease and Treatment Approaches
- Anesthesia and Pain Management
- Cardiac Imaging and Diagnostics
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac electrophysiology and arrhythmias
- Traumatic Ocular and Foreign Body Injuries
- Cardiac Arrhythmias and Treatments
- Foreign Body Medical Cases
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Venous Thromboembolism Diagnosis and Management
- Musculoskeletal pain and rehabilitation
- Musicians’ Health and Performance
Aarhus University Hospital
2012-2023
Odense University Hospital
2023
Aarhus University
1991-2022
University College Hospital
2016
University College London
2016
King's College School
2016
King's College London
2016
Danish Society of Cardiology
2007
Vejle Sygehus
1997
University of California, San Diego
1989
The aims of the study were to examine prognostic value pre-operative left ventricular systolic and diastolic function on early, late mortality after valve replacement for aortic stenosis, identify possible underlying mechanisms. Ninety-one prospectively recruited consecutive patients with a mean age 61 years underwent stenosis concomitant coronary artery bypass grafting in 32 minimum postoperative observation period 5·4 years. There six early (≤30 days postoperatively) 19 deaths, 18 deaths...
Several studies have shown that placebo analgesia effects can be obtained in healthy volunteers, as well patients suffering from acute postoperative pain and chronic conditions such irritable bowel syndrome. However, it is unknown whether elicited with a known pathophysiology nerve injury. Nineteen who had developed neuropathic after thoracotomy were exposed to manipulation which they received either open or hidden administrations of lidocaine. Before the treatment, rated their levels...
Research on placebo analgesia and nocebo hyperalgesia has primarily included healthy subjects or acute pain patients, it is unknown whether these effects can be obtained in ongoing patients with chronic caused by an identifiable nerve injury. Eighteen postthoracotomy neuropathic were exposed to manipulations, which they received open hidden administrations of pain-relieving (lidocaine) pain-inducing (capsaicin) treatment controlled for the natural history pain. Immediately after...
Background Variability in patients' postoperative pain experience and response to treatment challenges effective management. reflects individual differences inhibitory modulation psychological sensitivity, which turn may be clinically relevant for the disposition acquire pain. The aim of this study was investigate effects conditioned situational catastrophizing on persistency. Methods Preoperatively, 42 healthy males undergoing funnel chest surgery completed Spielberger's State-Trait Anxiety...
In a prospective study 99 consecutive patients with operative indication due to severe aortic stenosis (AS) were put on surgical waiting list. The waiting-time valve replacement (AVR) averaged 6.3 months (0.5-19 months). There 58 men and 41 women mean age of 61 years (21-82 years). divided into three groups: group I (n = 81) an uneventful stay the list (including one patient who declined AVR offer); II 11) significant worsening prognostic index; III 7) died during waiting-time. waiting-list...
The prevalence of pectus excavatum is low but many patients are disabled from this thoracic deformity. Nuss operation a well-established surgical correction, however, until recently it has been rarely used in Europe. We have performed the regularly between 2001 and 2006 where total 383 were operated on for excavatum. indication surgery was disabling cosmetic appearance as described by patient. Patient records reviewed retrospective analysis. median age 16 years (range 7-43) 86% males. A...
Patients with pectus excavatum have compromised cardiac function during exercise. We hypothesized that the Nuss technique would improve cardiopulmonary investigated 75 teenagers (49 patients and 26 controls) at rest bicycle exercise prior to surgery 1 year postoperative. Prior surgery, had a lower index 6.6 ± 1.1 l/min/m2 when compared controls 8.1 1.0 submaximal exercise, P = 0.0001. There was no difference in heart rate or increase between two groups. One after significantly increased...
Key points We studied the effects of antihypertensive calcium channel blockers on Ca V 1.2, predominantly expressed L‐type in largest human lymphatic vessel, thoracic duct. Human collecting vessels, both large and small, are highly‐sensitive vitro to blockers; exposure these drugs inhibits endogenous contractile activity action potentials diminishes noradrenaline‐induced phasic contractions. In vivo administration blocker nifedipine healthy volunteers did not reduce despite all subjects...
To evaluate the effect of perioperative gabapentin treatment for prevention persistent post-thoracotomy pain and to establish whether has a significant therapeutic impact on acute postoperative pain. Consecutive patients with pulmonary malignancies scheduled anterior thoracotomy were enrolled in this randomized, double-blinded, placebo-controlled trial. Patients given 1200 mg or placebo 2 h before surgery followed by increasing doses during 5 days: 600 day 1; 900 2; days 3–5. Effective...
The impact of correction pectus excavatum (PE) on adolescents' health-related quality life (HRQL) has only been investigated in prospective designs using disease-specific measures and without controls. aim this study was to evaluate the HRQL before after surgical PE a generic measure, compare reported level surgery with an age-comparable control group.Patients (n=107) one their parents (n=106) completed measure: Child Health Questionnaire before, 3 months, 6 months for PE. A group (n=183)...
Patients with mechanical heart valves require lifelong oral anticoagulant treatment which entails frequent blood sampling and dosage adjustment. The purpose of this study was to investigate the feasibility letting valve operated patients manage specimen analysis adjustment themselves.A total 21 were enrolled in followed for at least 9 months postoperatively. Immediately after operation they trained operating a CoaguChek international normal ratio (INR) monitor analyze capillary whole...
Introduction: This study evaluated health-related quality of life (HRQoL) in children and adolescents undergoing cosmetic surgery for pectus excavatum (PE) compared to a group healthy children.
In 1998 The Danish Lung Cancer Group published the first edition of guidelines for diagnosis and treatment lung cancer. A national registry was implemented in year 2000 with primary objective to monitor implementation these nationwide secure improve quality clinical management results this effort are reported special focus on surgery.Through systematic registration a total 24,153 patients have been included period 2000-2007. Indicators describing staging, surgical procedures, complications...
The current study characterizes the mechanical properties of human thoracic duct and demonstrates a role for adrenoceptors, thromboxane, endothelin receptors in lymph vessel function. With ethical permission informed consent, portions (2-5 cm) were resected retrieved at T(7)-T(9) during esophageal cardia cancer surgery. Ring segments (2 mm long) mounted myograph isometric tension (N/m) measurement. diameter-tension relationship was established using ducts from 10 individuals. Peak active...