- Mosquito-borne diseases and control
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Vector-borne infectious diseases
- COVID-19 epidemiological studies
- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- Viral Infections and Immunology Research
- Viral Infections and Outbreaks Research
- vaccines and immunoinformatics approaches
Faculdade de Medicina de São José do Rio Preto
2020-2025
The emergence of the Brazilian variant concern, Gamma lineage (P.1), impacted epidemiological profile COVID-19 cases due to its higher transmissibility rate and immune evasion ability.
Background Chikungunya virus (CHIKV) has spread across Brazil with varying incidence rates depending on the affected areas. Due to cocirculation of arboviruses and overlapping disease symptoms, CHIKV infection may be underdiagnosed. To understand lack epidemics in São José do Rio Preto (SJdRP), Paulo (SP), Brazil, we evaluated viral circulation by investigating anti-CHIKV IgG seroconversion a prospective study asymptomatic individuals detecting IgM suspected dengue infection, as well...
Pneumonia and diarrhea are the leading causes of death in children under 5 globally, worsened by viral infections. This study investigates agents ≤3 years with respiratory illness Metropolitan Region São Paulo, Brazil, during spring 2021. Twenty paired samples (oropharyngeal swab feces) were tested using in-house qPCR for HBoV HAdV, RT-qPCR RVA, EV, PeV-A, NoV, a commercial kit SARS-CoV-2, Flu A/B, RSV. HAstV was detected conventional nested (RT)-PCR. Positive sequenced molecular...
Ilheus virus is an arbovirus with the potential for central nervous system involvement. Accurate diagnosis a challenge due to similar clinical symptoms and serologic cross-reactivity other flaviviruses. Here, we describe first documented case of fatal outcome following identification in cerebrospinal fluid (CSF) patient cerebral encephalitis Brazil.
Arbovirus infections are increasingly important causes of disease, whose spectrum neurological manifestations not fully known. This study sought to retrospectively assess the incidence arboviruses in cerebrospinal fluid samples patients with symptoms inform diagnosis central and peripheral nervous system disorders. A total 255 (CSF) collected from January 2016 December 2017 were tested for dengue virus (DENV 1-4), Zika (ZIKV), Chikungunya (CHIKV) addition other neurotropic interest, using...
Enterovirus (EV) is commonly associated with central nervous system (CNS) syndromes. Recently, gastroenteric viruses, including rotavirus (RVA), human astrovirus (HAstV), and norovirus (NoV), have also been CNS neurological disorders. The aim of the present study was to investigate presence EV, RVA, HAst, NoV infections undiagnosed etiology in Northwest region São Paulo State, Brazil, conduct molecular characterization positive samples detected. A total 288 cerebrospinal fluid collected from...
Abstract The emergence of the new Brazilian variant concern, P.1 lineage (Gamma), raised concern about its impact on epidemiological profile COVID-19 cases due to higher transmissibility rate and immune evasion ability. Using 272 whole-genome sequences combined with data, we showed that introduction in São José do Rio Preto, Paulo, Brazil, was followed by displacement eight circulating SARS-CoV-2 variants a rapid increase prevalence two months after first detection. Our findings support is...