A5086611624- Neural dynamics and brain function
- Face Recognition and Perception
- Visual perception and processing mechanisms
- Functional Brain Connectivity Studies
- Multisensory perception and integration
- Memory and Neural Mechanisms
- EEG and Brain-Computer Interfaces
- Visual Attention and Saliency Detection
- Neural and Behavioral Psychology Studies
- Neuroscience and Neuropharmacology Research
- Child and Animal Learning Development
- Neuroscience and Music Perception
- Action Observation and Synchronization
- Memory Processes and Influences
- Face recognition and analysis
- Categorization, perception, and language
- Aesthetic Perception and Analysis
- Sleep and Wakefulness Research
- Evolutionary Psychology and Human Behavior
- Obsessive-Compulsive Spectrum Disorders
- Neuroendocrine regulation and behavior
- Advanced Memory and Neural Computing
- Image Retrieval and Classification Techniques
- Hearing Loss and Rehabilitation
- Cell Image Analysis Techniques
Université de Montréal
1994-2025
University of Birmingham
2017-2024
Mila - Quebec Artificial Intelligence Institute
2024
University of Cambridge
2014-2019
MRC Cognition and Brain Sciences Unit
2012-2019
Medical Research Council
2013-2018
University of Glasgow
2007-2013
Wellcome Centre for Human Neuroimaging
2009-2013
fMRI studies increasingly examine functions and properties of non-primary areas human auditory cortex. However there is currently no standardized localization procedure to reliably identify specific across individuals such as the standard 'localizers' available in visual domain. Here we present an 'voice localizer' scan allowing rapid reliable voice-sensitive 'temporal voice areas' (TVA) We describe results obtained using this localizer a large cohort normal adult subjects. Most participants...
Significance Everyone is different. Understanding the unique way an individual perceives world a fundamental goal of psychology and brain science. Using novel methods for analyzing functional MRI (fMRI) data, we show that each person viewing set objects represents uniquely in his or her brain. Moreover, given individual’s measured brain-activity patterns, idiosyncrasies perception similarities among can be predicted. Prediction accuracy modest using current technology. However, our results...
Massed synchronised neuronal firing is detrimental to information processing. When networks of task-irrelevant neurons fire in unison, they mask the signal generated by task-critical neurons. On a macroscopic level, such synchronisation can contribute alpha/beta (8-30 Hz) oscillations. Reducing amplitude these oscillations, therefore, may enhance Here, we test this hypothesis. Twenty-one participants completed an associative memory task while undergoing simultaneous EEG-fMRI recordings....
Advances in artificial intelligence have inspired a paradigm shift human neuroscience, yielding large-scale functional magnetic resonance imaging (fMRI) datasets that provide high-resolution brain responses to thousands of naturalistic visual stimuli. Because such experiments necessarily involve brief stimulus durations and few repetitions each stimulus, achieving sufficient signal-to-noise ratio can be major challenge. We address this challenge by introducing GLMsingle , scalable,...
Deep feedforward neural network models of vision dominate in both computational neuroscience and engineering. The primate visual system, by contrast, contains abundant recurrent connections. Recurrent signal flow enables recycling limited resources over time, so might boost the performance a physically finite brain or model. Here we show: (1) convolutional outperform matched their number parameters large-scale recognition tasks on natural images. (2) Setting confidence threshold, at which...
The degree to which we perceive real-world objects as similar or dissimilar structures our perception and guides categorization behavior. Here, investigated the neural representations enabling perceived similarity using behavioral judgments, fMRI MEG. As different object dimensions co-occur partly correlate, understand relationship between brain activity it is necessary assess unique role of multiple dimensions. We thus behaviorally assessed in relation shape, function, color background....
Significance How do we adaptively switch from perceiving the external world to retrieving goal-relevant internal memories? To tackle this question, used—in a cued-recall paradigm—direct intracranial recordings human hippocampus complemented by high-density scalp electroencephalography (EEG). We found that hippocampal signal ∼500 ms after perceptual cue marks conversion (perceptual) (mnemonic) representations. This sets in motion recall cascade involving posterior parietal and medial...
Memory consolidation-the transformation of labile memory traces into stable long-term representations-is facilitated by post-learning sleep. Computational and biophysical models suggest that sleep spindles may play a key mechanistic role for consolidation, igniting structural changes at cortical sites involved in prior learning. Here, we tested the resulting prediction are most pronounced over learning-related areas extent this learning-spindle overlap predicts behavioral measures...
Previous electrophysiological studies have identified a "voice specific response" (VSR) peaking around 320 ms after stimulus onset, latency markedly longer than the 70 needed to discriminate living from non-living sound sources and 150 200 for processing of voice paralinguistic qualities. In present study, we investigated whether an early difference between non-voice stimuli could be observed. ERPs were recorded 32 healthy volunteers who listened long three categories - voices, bird songs...
Aims: Emotional facial expression (EFE) decoding impairment has been repeatedly reported in alcoholism (e.g. Philippot et al., 1999). Nevertheless, several questions are still under debate concerning this alteration, notably its generalization to other emotional stimuli and variation according the valence of stimuli. Methods: Eighteen recently detoxified alcoholic subjects 18 matched controls performed a test consisting intensity ratings on various (faces, voices, body postures written...
The functional role of the superior temporal sulcus (STS) has been implicated in a number studies, including those investigating face perception, voice and face-voice integration. However, nature STS preference for these 'social stimuli' remains unclear, as does location within specific types information processing. aim this study was to directly examine properties terms selective response social stimuli. We used magnetic resonance imaging (fMRI) scan participants whilst they were presented...
It is presently unknown whether our response to affective vocalizations specific those generated by humans or more universal, triggered emotionally matched other species. Here, we used functional magnetic resonance imaging in normal participants measure cerebral activity during auditory stimulation with affectively valenced animal vocalizations, some familiar (cats) and others not (rhesus monkeys). Positively versus negatively from cats monkeys elicited different responses despite the...
Normal listeners effortlessly determine a person's gender by voice, but the cerebral mechanisms underlying this ability remain unclear. Here, we demonstrate 2 stages of processing during voice categorization. Using morphing along with an adaptation-optimized functional magnetic resonance imaging design, found that secondary auditory cortex including anterior part temporal areas in right hemisphere responded primarily to acoustical distance previously heard stimulus. In contrast, network...
Sleep stabilizes newly acquired memories, a process referred to as memory consolidation. According recent studies, sleep-dependent consolidation processes might be deployed different extents for types of memories. In particular, weaker memories benefit greater from post-learning sleep than stronger However, under standard testing conditions, effects obscured by ceiling effects. To test this possibility, we devised new paradigm (Memory Arena) in which participants learned temporospatial...
GLMdenoise is a denoising technique for task-based fMRI. In GLMdenoise, estimates of spatially correlated noise (which may be physiological, instrumental, motion-related, or neural in origin) are derived from the data and incorporated as nuisance regressors general linear model (GLM) analysis. We previously showed that outperforms variety other techniques terms cross-validation accuracy GLM (Kay et al., 2013a). However, practical impact experimental studies remains unclear. Here we examine...
Abstract Extensive sampling of neural activity during rich cognitive phenomena is critical for robust understanding brain function. We present the Natural Scenes Dataset (NSD), in which high-resolution fMRI responses to tens thousands richly annotated natural scenes are measured while participants perform a continuous recognition task. To optimize data quality, we develop and apply novel estimation denoising techniques. Simple visual inspections NSD reveal clear representational...
Abstract Converging, cross-species evidence indicates that memory for time is supported by hippocampal area CA1 and entorhinal cortex. However, limited characterizes how these regions preserve temporal memories over long timescales (e.g., months). At timescales, memoranda may be encountered in multiple contexts, potentially creating interference. Here, using 7T fMRI, we measured activity patterns as human participants viewed thousands of natural scene images distributed, repeated, across...
This study proposes a data-driven framework for enhancing the accuracy and efficiency of scientific peer review through an open, bottom-up process that estimates reviewer quality. Traditional closed systems, while essential quality control, are often slow, costly, subject to biases can impede progress. Here, we introduce method evaluates individual reliability by quantifying agreement with community consensus scores applying Bayesian weighting refine paper assessments. We analyze open data...
Binge drinking is now considered a central public health issue and associated with emotional interpersonal problems, but the neural implications of these deficits remain unexplored. The present study aimed at offering first insights into effects binge on processing vocal affect. On basis an alcohol-consumption screening phase (204 students), 24 young adults (12 drinkers 12 matched controls, mean age: 23.8 years) were selected performed categorisation task morphed stimuli (drawn from...