- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- EEG and Brain-Computer Interfaces
- Advanced Neuroimaging Techniques and Applications
- Neural dynamics and brain function
- Non-Invasive Vital Sign Monitoring
- Atomic and Subatomic Physics Research
- Neurological disorders and treatments
- Medical Imaging Techniques and Applications
- Medical Image Segmentation Techniques
- Hemodynamic Monitoring and Therapy
- Sleep and Work-Related Fatigue
- Surgical site infection prevention
- Blind Source Separation Techniques
- Retinal and Macular Surgery
- Brain Tumor Detection and Classification
- Diphtheria, Corynebacterium, and Tetanus
- Indoor and Outdoor Localization Technologies
- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Reconstructive Surgery and Microvascular Techniques
- Surgical Sutures and Adhesives
- Heart Rate Variability and Autonomic Control
- Orthopedic Infections and Treatments
- Pressure Ulcer Prevention and Management
Swiss Center for Electronics and Microtechnology (Switzerland)
2020-2024
École Polytechnique Fédérale de Lausanne
2014-2023
Centro Hospitalar de Lisboa Central
2015-2021
Centre d'Imagerie BioMedicale
2017-2020
University of Lausanne
2017-2020
Hospital Curry Cabral
2015-2019
University of Lisbon
2011-2018
INESC TEC
2012-2018
Instituto Superior Técnico
2011-2015
Instituto Politécnico de Lisboa
2012
Massed synchronised neuronal firing is detrimental to information processing. When networks of task-irrelevant neurons fire in unison, they mask the signal generated by task-critical neurons. On a macroscopic level, such synchronisation can contribute alpha/beta (8-30 Hz) oscillations. Reducing amplitude these oscillations, therefore, may enhance Here, we test this hypothesis. Twenty-one participants completed an associative memory task while undergoing simultaneous EEG-fMRI recordings....
Both electroencephalography (EEG) and functional Magnetic Resonance Imaging (fMRI) are non-invasive methods that show complementary aspects of human brain activity. Despite measuring different proxies activity, both the measured blood-oxygenation neurophysiological recordings indirectly coupled. The electrophysiological BOLD signal can map underlying connectivity structure at whole scale timescales. Previous work demonstrated a moderate but significant correlation between resting-state...
The central vein sign (CVS) is an efficient imaging biomarker for multiple sclerosis (MS) diagnosis, but its application in clinical routine limited by inter‐rater variability and the expenditure of time associated with manual assessment. We describe a deep learning‐based prototype automated assessment CVS white matter MS lesions using data from three different centers. retrospectively analyzed 3 T magnetic resonance images acquired on four scanners two vendors, including adults ( n = 42),...
The thalamus is a central component of the brain that involved in variety functions, from sensory processing to high-order cognition. Its structure and function first weeks extrauterine life, including its connections different cortical subcortical areas, have not yet been widely explored. Here, we used resting state functional magnetic resonance imaging data 730 newborns developing Human Connectome Project study organization 37 44 post-conceptual weeks. We introduce KNIT: K-means for Nuclei...
Purpose Physiological noise often dominates the blood‐oxygen level–dependent (BOLD) signal fluctuations in high‐field functional MRI (fMRI) data. Therefore, to optimize fMRI protocols, it becomes crucial investigate how physiological impact various acquisition and reconstruction schemes at different speeds. In particular, further differences can arise between 2D 3D acquisitions due encoding strategies, thereby impacting sensitivity potentially significant ways. Methods The amount of be...
Surgery is the first choice therapeutic approach in case of drug-resistant epilepsy. Unfortunately, up to 43% patients referred for presurgical assessment do not have a lesion detectable by routine 3T magnetic resonance imaging (MRI) (MRI-negative), although most them likely an underlying epileptogenic lesion. Thus, new MRI modalities with increased sensibility lesions are required. This paper describes magnetization-prepared two rapid acquisition gradient echoes (MP2RAGE) and...
Abstract The ventro-intermediate nucleus (Vim), as part of the motor thalamic nuclei, is a commonly used target in functional stereotactic neurosurgery for treatment drug-resistant tremor. As it cannot be directly visualized on routinely magnetic resonance imaging (MRI), its clinical targeting performed using indirect methods. Recent literature suggests that Vim can susceptibility-weighted (SWI) acquired at 7 T. Our work aims to assess distinguishable T SWI both healthy-population and...
Abstract External stimuli and tasks often elicit negative BOLD responses in various brain regions, growing experimental evidence supports that these phenomena are functionally meaningful. In this work, the high sensitivity available at 7T was explored to map characterize both positive (PBRs) (NBRs) visual checkerboard stimulation, occurring regions within beyond cortex. Recently‐proposed accelerated fMRI techniques were employed for data acquisition, procedures exclusion of large draining...
Blood pressure (BP) is a crucial biomarker giving valuable information regarding cardiovascular diseases but requires accurate continuous monitoring to maximize its value. In the effort of developing non-invasive, non-occlusive and BP devices, photoplethysmography (PPG) has recently gained interest. Researchers have attempted estimate based on analysis PPG waveform morphology, with promising results, yet often validated small number subjects moderate variations. This work presents an...
Conventional sleep monitoring is time-consuming, expensive and uncomfortable, requiring a large number of contact sensors to be attached the patient. Video data commonly recorded as part laboratory assessment. If accurate staging could achieved solely from video, this would overcome many problems traditional methods. In work we use heart rate, breathing rate activity measures, all derived near-infrared video camera, perform stage classification. We deep transfer learning approach scarcity,...
The thalamus is an important brain structure and neurosurgical target, but its constituting nuclei are challenging to image non-invasively. Recently, susceptibility-weighted imaging (SWI) at ultra-high field has shown promising capabilities for thalamic mapping. In this work, several methodological improvements were explored enhance SWI quality contrast, specifically ability imaging.High-resolution was performed 7T in healthy participants, the following techniques applied: (a) monitoring...
Abstract Simultaneous EEG‐fMRI allows multiparametric characterisation of brain function, in principle enabling a more complete understanding responses; unfortunately the hostile MRI environment severely reduces EEG data quality. Simply eliminating segments containing gross motion artefacts [MAs] (generated by movement system and head scanner's static magnetic field) was previously believed sufficient. However recently importance removal all MAs has been highlighted new methods developed. A...