A5031807880- Lung Cancer Research Studies
- Head and Neck Cancer Studies
- Lung Cancer Treatments and Mutations
- Esophageal Cancer Research and Treatment
- MicroRNA in disease regulation
- Head and Neck Surgical Oncology
- Computational Drug Discovery Methods
- Cancer therapeutics and mechanisms
- Cervical Cancer and HPV Research
- Semiconductor materials and devices
- Esophageal and GI Pathology
- Neuroendocrine Tumor Research Advances
- Chromatin Remodeling and Cancer
- RNA modifications and cancer
- Pharmacovigilance and Adverse Drug Reactions
- Breast Cancer Treatment Studies
- Statistical Methods in Clinical Trials
- Cancer Immunotherapy and Biomarkers
- Endometrial and Cervical Cancer Treatments
- Tracheal and airway disorders
- Brain Metastases and Treatment
- Colorectal and Anal Carcinomas
- Cancer Diagnosis and Treatment
- Oral health in cancer treatment
- Lung Cancer Diagnosis and Treatment
South China University of Technology
2022-2025
Southern Medical University
2016-2020
Zhujiang Hospital
2016-2019
Induction chemotherapy added to concurrent chemoradiotherapy significantly improves survival for patients with locoregionally advanced nasopharyngeal carcinoma, but the optimal induction regimen remains unclear.To determine whether paclitaxel, cisplatin, and capecitabine (TPC) vs cisplatin fluorouracil (PF) prior stage IVA IVB carcinoma.This randomized, open-label, phase 3 clinical trial recruited 238 at 4 hospitals in China from October 20, 2016, August 29, 2019. Patients were 18 65 years...
Objective: To compare survival outcomes between cervical adenocarcinoma (ADC) and squamous cell carcinoma (SCC) using a propensity score matching (PSM) analysis based on the Surveillance, Epidemiology, End Results (SEER) Program.Methods: Patients diagnosed with cancer 1998 2016 were identified from SEER database.The Kaplan-Meier method Cox regression used to analyze survival.A subgroup of overall (OS) patients ADC SCC was performed after 1:1 PSM analysis.Results: Of 33,148 patients, 24,591...
Purpose The objective of the study is to systematically identify and evaluate adverse drug reactions (ADRs) associated with combination therapy bevacizumab in patients unresectable hepatocellular carcinoma (HCC). Patients methods Data were extracted from Food Drug Administration (FDA) Adverse Event Reporting System FDA database. Disproportionality analysis was conducted using reporting odds ratio (ROR), proportional (PRR) Bayesian confidence propagation neural network (BCPNN) information...
Current evidence for the combined use of immunotherapy, low-dose chemoradiotherapy, and epidermal growth factor receptor-targeted therapy treatment advanced esophageal squamous cell carcinoma is lacking. We report case a 73-year-old woman with upper middle thoracic esophagus. After undergoing concurrent chemoradiotherapy immunotherapy anti-angiogenic targeted therapy, patient achieved progression-free survival 17 months. To date, has 35 months overall survival, which continues to extend,...
The precise incidence of immune-related adverse events (irAEs) remains unclear. This pharmacovigilance study investigated acute pancreatitis (AP) associated with immune checkpoint inhibitors (ICIs) using real-world data from the FDA Adverse Event Reporting System (FAERS). Disproportionality analysis employing reporting odds ratios (RORs) was conducted to detect AP signals in ICI-treated patients compared entire FAERS database. A total 152,042 individual were included dataset which we...
Rationale: Chemoresistance frequently occurs in patients with small cell lung cancer (SCLC) and leads to a dismal prognosis.However, the mechanisms underlying this process remain largely unclear. Methods:The effects of chromodomain Y-like (CDYL) on chemoresistance SCLC were determined using Western blotting, immunohistochemistry, counting kit-8 assays, flow cytometry, tumorigenicity experiments, investigated mRNA sequencing, chromatin immunoprecipitation-qPCR, electrophoretic mobility shift...
Objective: This study aimed to establish a simplified T classification based on the 8th edition of Union for International Cancer Control/American Joint Committee (UICC/AJCC) staging system nasopharyngeal carcinoma (NPC). Methods: In total, 325 patients with NPC were included in this study. All underwent magnetic resonance imaging, and criteria recorded. These subjected UICC/AJCC NPC. Results: Involvement oropharynx, nasal cavity, adjacent soft tissue (medial pterygoid, lateral prevertebral...
Third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are highly effective against tumors harboring the T790M mutation. However, patients treated with these ultimately develop resistance, and most common mechanism is emergence of EGFR C797S Few treatment regimens have been reported for this condition. In report, we present a successful combination programmed cell death 1 (PD-1) inhibitor sintilimab, anti-vascular endothelial (VEGF) therapy, chemotherapy...
Objective To observe the effect and safety of home-made metallic stent implantation in treatment malignant esophageal stricture. Methods Among 47 cases with stricture, there were 8 superior esophagus, 12 middle esophagus,27 inferior gastric cardia carcinoma. Those not suitable or willing to accept surgical operation. Before stenting, radiotherapies done all cases. Different shape stents used place segment structure via mouth according positions diameters The follow-up periods was 5 ～ 16...
Objective: The aim of this study was to explore the patterns retropharyngeal lymph node (RLN) metastasis in nasopharyngeal carcinoma (NPC) and their impact on clinical target volume (CTV) delineation radiotherapy. Methods: A total 190 patients with untreated, nonmetastatic NPC received MRI scans nasopharynx neck before treatment. imaging characteristics RLN relationships staging system were analysed. Results: 121 developed metastasis. incidence rate 63.7%. metastases distributed evenly...