A5045563749- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- COVID-19 Clinical Research Studies
- Phagocytosis and Immune Regulation
- Heart Failure Treatment and Management
- Respiratory Support and Mechanisms
- Acute Myocardial Infarction Research
- Atherosclerosis and Cardiovascular Diseases
- Quantum Dots Synthesis And Properties
- Diamond and Carbon-based Materials Research
- Cardiomyopathy and Myosin Studies
- Ultrasound in Clinical Applications
- Long-Term Effects of COVID-19
- Non-Invasive Vital Sign Monitoring
- Cardiovascular Issues in Pregnancy
- Sepsis Diagnosis and Treatment
- TiO2 Photocatalysis and Solar Cells
- Paraoxonase enzyme and polymorphisms
- Advanced Photocatalysis Techniques
- Hemodynamic Monitoring and Therapy
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
Beth Israel Deaconess Medical Center
2021-2023
Harvard University
2023
Georgia Institute of Technology
2015
Conventional squaraine dyes exhibit an intense absorption band in the red region of solar spectrum and with appropriate design can also have high energy as well, making them interesting building blocks toward achieving panchromatic for dye sensitized cell (DSSC) applications. In this report, eight thiophene, 4-hexyl-4H-dithieno[3,2-b:2′,3′-d]pyrrole, dithieno[3,2-b:2′,3′-d]thiophene, 4,4-bis(2-ethylhexyl)-4H-silolo[3,2-b:4,5-b′]dithiophene (DTS) π-bridges cyanoacetic acid (CA)...
Endothelial dysfunction accompanies the microvascular thrombosis commonly observed in severe COVID-19. Constitutively, endothelial surface is anticoagulant, a property maintained at least part via signaling through Tie2 receptor. During inflammation, antagonist angiopoietin-2 (Angpt-2) released from cells and inhibits Tie2, promoting prothrombotic phenotypic shift. We sought to assess whether COVID-19 associated with procoagulant alterations Tie2/angiopoietin axis. Primary HUVECs treated...
BackgroundFemale sex is frequently cited as a risk factor for anthracycline cardiotoxicity based on pediatric data, but the role of in development has not been clearly established adults.ObjectivesTo assess effect female incident heart failure (HF) adult patients treated with anthracyclines.MethodsThis was retrospective cohort study 1,525 no prior history HF or cardiomyopathy who were anthracyclines between 1992 and 2019. The primary outcome new within 5 years first dose anthracyclines....
Anthracyclines are effective chemotherapies that limited by cardiotoxicity. The spatial ventricular gradient (SVG) is a marker of electrical heterogeneity linked to adverse cardiovascular outcomes, including sudden cardiac death and heart failure (HF). purpose this study was assess if SVG values before chemotherapy associated with the risk anthracycline-associated HF or cardiomyopathy (CM). We analyzed 12-lead electrocardiograms obtained within 6 months initiation anthracyclines in...
Profound endothelial dysfunction accompanies the microvascular thrombosis commonly observed in severe COVID-19. In quiescent state, surface is anticoagulant, a property maintained at least part via constitutive signaling through Tie2 receptor. During inflammation, antagonist angiopoietin-2 (Angpt-2) released from activated cells and inhibits Tie2, promoting prothrombotic phenotypic shift. We sought to assess whether COVID-19 associated with procoagulant of endothelium alterations...
Introduction and Hypothesis: Female sex has long been considered a risk factor for anthracycline-associated cardiotoxicity, based largely on data in childhood cancer survivors. However, preclinical experiments suggest that female hormones present adulthood may protect against doxorubicin cardiotoxicity. We therefore hypothesized would be associated with decreased odds of heart failure adult patients treated anthracyclines. Methods: conducted retrospective cohort study 871 (44% women 56% men)...