A5028616305- Suicide and Self-Harm Studies
- Sleep and related disorders
- Sleep and Wakefulness Research
- Obstructive Sleep Apnea Research
- Functional Brain Connectivity Studies
- Neuroscience of respiration and sleep
- Advanced Neuroimaging Techniques and Applications
- Mental Health Research Topics
- Advanced MRI Techniques and Applications
- Health and Wellbeing Research
- Mental Health Treatment and Access
- Heart Rate Variability and Autonomic Control
- Treatment of Major Depression
- Psychosomatic Disorders and Their Treatments
- Sleep and Work-Related Fatigue
- Schizophrenia research and treatment
- Neurotransmitter Receptor Influence on Behavior
- Bipolar Disorder and Treatment
- Dementia and Cognitive Impairment Research
- Homicide, Infanticide, and Child Abuse
- Medical Imaging Techniques and Applications
- Pathogenesis and Treatment of Hiccups
- Health disparities and outcomes
- Obsessive-Compulsive Spectrum Disorders
- Posttraumatic Stress Disorder Research
Gachon University
2018-2025
Gachon University Gil Medical Center
2015-2023
Seoul National University Bundang Hospital
2022
Ewha Womans University
2022
Harvard University
2022
Maria Fertility Hospital
2020-2022
National Medical Center
2020-2022
Brigham and Women's Hospital
2022
Massachusetts General Hospital
2022
CHA Bundang Medical Center
2021
Nowadays, an infectious disease outbreak is considered one of the most destructive effects in sustainable development process. The new coronavirus (COVID-19) as showed that it has undesirable social, environmental, and economic impacts, leads to serious challenges threats. Additionally, investigating prioritization parameters vital importance reducing negative impacts this global crisis. Hence, main aim study prioritize analyze role certain environmental parameters. For purpose, four cities...
Panic disorder is a highly prevalent psychiatric that substantially impairs quality of life and psychosocial function. arises from neurobiological substrates developmental factors distinguish it other anxiety disorders. Differential diagnosis between panic disorders has only been conducted in terms phenomenological spectrum.Through machine learning-based approach with heart rate variability (HRV) as input, we aimed to build algorithms can differentiate Five were used: random forest (RF),...
This study aimed to investigate the applicability of machine learning predict obstructive sleep apnea (OSA) among individuals with suspected OSA in South Korea. A total 92 clinical variables for were collected from 279 Koreans (OSA, n = 213; no OSA, 66), which seven major indices selected. The data randomly divided into training 149; 46) and test 64; 20). Using indices, prediction models trained using four types models—logistic regression, support vector (SVM), random forest, XGBoost...
Objective This study aimed to introduce a 4-week long fully immersive virtual reality-based cognitive training (VRCT) program that could be applied for both cognitively normal elderly population and patients with mild impairment (MCI). In addition, we attempted investigate the neuropsychological effects of VRCT in each group.Methods A total 56 participants, 31 MCI group 25 group, underwent eight sessions 4 weeks. order evaluate VRCT, Korean version Consortium Establish Registry Alzheimer’s...
Patients with simple snoring (SS) often complain of poor sleep quality despite a normal apnoea-hypopnoea index (AHI). We aimed to identify the difference in power spectral density electroencephalography (EEG) between patients SS and those obstructive apnoea (OSA). compared absolute values standard EEG frequency bands (n = 42) OSA 129) groups during non-rapid eye movement (NREM) period, after controlling for age sex. also analysed partial correlation AHI bands. The beta delta were higher...
Suicide poses a serious problem globally, especially among the elderly population. To tackle issue, this study aimed to develop model for predicting suicide by using machine learning based on obtain large sample, used big data health screening cohort provided National Health Insurance Sharing Service. By applying technique, predictive that comprehensively utilized various factors was developed select aged > 65 years at risk of suicide. A total 48,047 subjects were included in analysis....
Depression is one of the leading causes disability worldwide. Given socioeconomic burden depression, appropriate depression screening for community dwellers necessary. We used data from 2014 and 2016 Korea National Health Nutrition Examination Surveys. The dataset was as a training set, whereas hold-out test set. synthetic minority oversampling technique (SMOTE) to control class imbalances between non-depression groups in dataset. least absolute shrinkage selection operator (LASSO) feature...
The habenula (Hb) has been hypothesized to play an essential role in major depressive disorder (MDD) as it is considered be important node between fronto-limbic areas and midbrain monoaminergic structures based on animal studies. In this study, we aimed investigate the differences volume T1 value of Hb patients with MDD healthy control (HC) subjects. Analysis for volumes was performed using high-resolution 7-T magnetic resonance (MR) image data from 33 36 Two researchers blinded clinical...
Insomnia is a common disorder that affects vast number of patients; the hyperarousal theory insomnia postulates patients with are physiologically activated not only at nighttime but also during daytime. We aimed to investigate differences in resting-state functional connectivity (RSFC) thalamus cortical areas between and healthy controls.All participants completed clinical questionnaires underwent portable polysomnography fMRI.Patients group (n = 50) showed increased RSFC right medial...
Previous spectral analysis studies on obstructive sleep apnea (OSA) involved small samples, and the results were inconsistent. We performed a of EEG based different severities OSA using Sleep Heart Health Study data. This study aimed to determine difference in power during non-OSA group with general population.The participants (n = 5,804) underwent polysomnography, they classified into non-OSA, mild OSA, moderate severe groups. The fast Fourier transformation was used compute spectrum for...
Abstract Background Cognitive reserve (CR) is a concept proposed to account for discrepancies between the extent of brain pathology and clinical manifestations that pathology. This study aimed explore associations CR effects cognitive training using fully immersive virtual reality (VR). Methods A total 44 older adults (22 cognitively normal, 22 with mild impairment) underwent eight sessions VR period 4 weeks. was assessed Reserve Index questionnaire (CRIq). To evaluate baseline function...
Abstract The habenula is one of the most important brain regions for investigating etiology psychiatric diseases such as major depressive disorder (MDD). However, challenging to delineate with naked human eye in imaging due its low contrast and tiny size, manual segmentation results vary greatly depending on observer. Therefore, there a great need automatic quantitative analytic methods research purposes. Here we propose an automated volume estimation method 7 Tesla magnetic resonance based...
Abnormalities in myelin are believed to be one of the important causes major depressive disorder, and it is becoming more accurately quantify vivo magnetic resonance imaging disorder patients. We aimed investigate difference concentration white matter subcortical areas using new quantitative myelin-related maps high-resolution 7 Tesla (7 T) between patients with healthy controls. Myelin-related comparisons nearby regions were conducted controls (n = 36) 34). Smoothed ratio (sq-Ratio) created...
Continuous positive airway pressure (CPAP) is the preferred treatment for obstructive sleep apnea (OSA). However, compliance with CPAP therapy varies among studies, and studies on its predictors are insufficient in Korea. This study aimed to identify factors that predict patients OSA.
Abstract Previous spectral analysis studies on insomnia have shown inconsistent results due to their heterogeneity and small sample sizes. We compared the difference of electroencephalogram (EEG) power during sleep among participants without insomnia, insomniacs with no hypnotic use, users complaints, complaints using Sleep Heart Health Study data, which is large size has good quality control. The fast Fourier transformation was used calculate EEG spectrum for total duration within...