A5073385481- Neuroscience of respiration and sleep
- Neonatal Respiratory Health Research
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Neonatal and fetal brain pathology
- Emergency and Acute Care Studies
- Restraint-Related Deaths
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Vaccine Coverage and Hesitancy
- Health, Medicine and Society
- Influenza Virus Research Studies
- Trauma and Emergency Care Studies
- Pediatric Pain Management Techniques
- Radiation Dose and Imaging
- Respiratory and Cough-Related Research
- Autopsy Techniques and Outcomes
- Diabetes and associated disorders
- Sepsis Diagnosis and Treatment
- S100 Proteins and Annexins
- Clinical Reasoning and Diagnostic Skills
- Spinal Fractures and Fixation Techniques
- Bacterial Infections and Vaccines
- Viral gastroenteritis research and epidemiology
- Prenatal Substance Exposure Effects
Centre Hospitalier Universitaire de Nantes
2014-2024
Nantes Université
2017-2024
Inserm
2018-2024
Centre d'Investigation Clinique de Nantes
2018-2024
Centre d'Immunologie et des Maladies Infectieuses
2021
Hôpital Femme Mère Enfant
2018-2020
Hôpital Mère-Enfant
2012-2018
Université de Montpellier
2018
Centre Hospitalier Universitaire de Montpellier
2018
Hôpital Antoine-Béclère
2018
ABSTRACT In September 2023, France was one of the first countries that started a national immunisation campaign with nirsevimab, new monoclonal antibody against respiratory syncytial virus (RSV). Using data from network paediatric intensive care units (PICUs), we aimed to estimate nirsevimab effectiveness severe cases RSV bronchiolitis in France. We conducted case–control study based on test‐negative design and included 288 infants reported by 20 PICUs. estimated at 75.9% (48.5–88.7) main...
<h3>Importance</h3> In several countries, 5 years after 13-valent pneumococcal conjugate vaccine (PCV13) implementation, serotype replacement has been reported for invasive disease, which raises concerns about the long-term outcome of PCV13 implementation. The effect vaccination on community-acquired pneumonia (CAP) remains unknown. <h3>Objective</h3> To assess implementation CAP in children. <h3>Design, Setting, and Participants</h3> This quasi-experimental, population-based, interrupted...
Abstract We describe here changes in the bacterial causes of pleural empyema before and after implementation 13-valent pneumococcal conjugate vaccine (PCV13) program France (2009–2017). For 220 (39.3%) 560 children, a cause was found. The frequency infection decreased during study from 79.1% 2009 to 36.4% 2017 (P < .001). Group A streptococcus is now leading documented (45.5%).
Introduction Even after ‘back-to-sleep’ campaigns, sudden unexpected infant death (SUID) continues to be the leading cause of for infants 1 month year old in developed countries, with devastating social, psychological and legal implications families. To sustainably tackle this problem decrease number SUIDs, a French SUID registry was initiated 2015 (1) inform prevention standardised data, (2) understand mechanisms contribution already known or newly suggested risk factors (3) gather...
Misuse of antibiotics is largely responsible for the emergence bacterial resistance. Children represent a subset population who frequently receive antibiotics. The objectives were to calculate frequency antibiotic prescriptions that do not comply with best practice recommendations in paediatrics primary care and examine thoughts feelings physicians parents about prescription from national health authorities. We included children admitted at paediatric emergency room (PER) NANTES university...
Minor head trauma is a common reason for consultation in pediatric emergency departments. In 2009, the Pediatric Emergency Care Applied Research Network (PECARN) published clinical decision rule its management. It aimed to help clinicians identify children with very low risk of developing intracranial lesions, so that unnecessary cranial computed tomography (CCT) scan radiation could be avoided, as such exposure associated rising cancer this young population. meantime, serum S100β...
Lower respiratory tract infection is a common cause of consultation and antibiotic prescription in paediatric practice. The misuse antibiotics major the emergence multidrug-resistant bacteria. aim this study was to evaluate frequency, changes over time, determinants non-compliance with recommendations for children admitted emergency department (PED) community-acquired pneumonia (CAP). We conducted prospective two-period using data from French network that included all CAP, aged one month 15...
Objective(s): Blood cultures (BC), when performed in children seen the emergency department with community-acquired pneumonia (CAP), are most of time sterile. We described diagnostic accuracy white blood cells (WBC), absolute neutrophils count (ANC), C-reactive protein (CRP), and procalcitonin (PCT) to predict culture (BC) result childhood CAP. Study Design: Secondary analysis a prospective study carried out eight pediatric departments (France, 2009-2018), including (≤15 years) Analyses...
Non-pharmaceutical interventions (NPIs) against coronavirus disease 2019 were implemented in March 2020. These measures followed by a major impact on viral and non-viral diseases. We aimed to assess the of NPI implementation France hospitalized community-acquired pneumonia (hCAP) frequency clinical biological characteristics remaining cases children. performed quasi-experimental interrupted time-series analysis. Between June 2014 December 2020, eight pediatric emergency departments...