A5085174270- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- Phytoestrogen effects and research
- Animal Behavior and Welfare Studies
- Biochemical Analysis and Sensing Techniques
- Effects of Environmental Stressors on Livestock
- RNA modifications and cancer
- MicroRNA in disease regulation
- Animal Nutrition and Physiology
- Ruminant Nutrition and Digestive Physiology
- Alkaloids: synthesis and pharmacology
- Genetic Associations and Epidemiology
- Sirtuins and Resveratrol in Medicine
- Bee Products Chemical Analysis
- Genetics and Plant Breeding
- Circular RNAs in diseases
- Berberine and alkaloids research
- Dermatology and Skin Diseases
- Gut microbiota and health
- Traditional and Medicinal Uses of Annonaceae
- Reproductive Physiology in Livestock
Shanghai Jiao Tong University
2020-2024
University of Veterinary and Animal Sciences
2021-2022
Lahore Garrison University
2021
The research on genetic characterization of Chinese indigenous pig breeds is essential to promote scientific conservation and sustainable development pigs. Here, we systematically surveyed the genomes 75 unrelated Diannan small-ear (DSE) pigs that were from 3 diverse regions (Yingjiang County, Jinping County Sipsongpanna in Yunnan Province) describe their population structure, diversity, inbreeding coefficient, selection signatures. First, these individuals sequenced genotyped following...
Abstract Background China is the country with most abundant swine genetic resources in world. Through thousands of years domestication and natural selection, pigs have developed unique characteristics. Finding characteristics modules each breed an essential part their precise conservation. Results In this study, we used partial least squares method to identify significant specific SNPs 19 local Chinese pig breeds 5 Western breeds. A total 37,514 ( p < 0.01) were obtained from these...
Abstract Excessive fat deposition can trigger metabolic diseases, and it is crucial to identify factors that break the link between diseases. Healthy obese Laiwu pigs (LW) are high in content but resistant In this study, we compared fecal microbiome, blood metabolome, genome of LW Lulai (LU) block Our results show significant differences Spirochetes Treponema , which involved carbohydrate metabolism, LU. The metabolome composition was similar, some anti-metabolic disease components...
Summary Anqing six‐end‐white (AQ) pig performs well on resistance to coarse fodder and disease, reproduction meat quality, offering high potential for exploitation. Environmental conditions strict selections from local farmers have cultivated the AQ be an outstanding unique breed. Thus we aim detect genetic positive selection signatures within population explore underlying mechanisms. A relative extended haplotype homozygosity (REHH) test was performed in of 79 pigs seek evidence...
Statistical models play a significant role in designing competent breeding programs related to complex traits. Recently; the holo-omics framework has been productively utilized trait prediction; but it contains many complexities. Therefore; is desirable establish prediction accuracy while combining host’s genome and microbiome data. Several methods can be used combine two data model study their effectiveness by estimating accuracy. We validate our interaction with analysis from publicly...
Genome-wide association studies (GWAS) significantly enhance our ability to identify trait-associated genomic variants by considering the host genome. Moreover, hologenome refers organism’s collective genetic material and its associated microbiome. In this study, we utilized framework, called Hologenome-wide (HWAS), dissect architecture of complex traits, including milk yield, methane emissions, rumen physiology in cattle, gut microbial composition pigs. We employed four statistical models:...
Both selection and mating systems are essential tools for breeders to conserve the genetic variance improve performance of livestock animals. How effectively balance gain inbreeding has always been an important issue in quantitative genetics research. In this study, a total 11 methods, including random truncation selection, six conventional three different optimal contribution (OCS) methods strategies mating, minimum-coancestry based on pedigree (MCPed) genomic information (MCmarker), were...
Genomic selection (GS) techniques have improved animal breeding by enhancing the prediction accuracy of values, particularly for traits that are difficult to measure and low heritability, as well reducing generation intervals. However, requirement establish genetic reference populations can limit application GS in pig breeds with small populations, especially when make up most worldwide. We aimed propose a kinship index based (KIS) method, which defines an ideal individual information on...
Construction of kinship matrices among individuals is an important step for both association studies and prediction based on different levels omic data. Methods constructing are becoming diverse methods have their specific appropriate scenes. However, software that can comprehensively calculate a variety scenarios still in urgent demand.
Abstract Background China has rich and vast genetic resources of indigenous pig breeds. Currently, great attention is paid to either crossbreeding or conservation these breeds, insufficient the combination breeding along with their long-term effects on diversity. The diversity livestock essential increase productivity respond future challenges such as climate change. stability product consistency breeds should be focused further improved. Therefore, objective this study compare using...