A5046081796- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Hormonal and reproductive studies
- Gut microbiota and health
- Trace Elements in Health
- Cancer-related molecular mechanisms research
- Advanced Radiotherapy Techniques
- Radiopharmaceutical Chemistry and Applications
- Folate and B Vitamins Research
Kindai University
2024-2025
Kindai University Hospital
2024
The efficacy of abiraterone acetate varies among patients with high-risk metastatic castration-sensitive prostate cancer (mCSPC). Both androgen receptor (AR) and cytokeratin 18 (CK18) are markers the luminal lineage cancer, their expression levels have been suggested to affect response deprivation therapy (ADT). This study aimed predict in mCSPC via immunohistochemical staining biopsy specimens obtained at time diagnosis. We retrospectively analyzed 44 treated combination ADT. AR CK18 were...
Abstract Background Prostate cancer is a complex disease that develops over time and influenced by several lifestyle factors also impact gut microbes. Gut dysbiosis intricately linked to prostate carcinogenesis, but the precise mechanisms remain poorly understood. Mice are crucial for studying relationships between microbes cancer, discovering similarities humans mice may aid in elucidating new mechanisms. Methods We used 16s rRNA sequencing data from stool samples of tumor‐bearing...
Abstract Gut microbiota plays a crucial role in the development and progression of prostate cancer, with previous studies indicating that certain bacterial taxa are more abundant castration‐resistant cancer (CRPC) compared to hormone‐sensitive (HSPC). Notably, composition gut can vary significantly by geographic region, Japanese individuals have distinct microbial profile. However, research exploring these differences within populations remains limited. This study investigated between men...