- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Neurosurgical Procedures and Complications
- Neurological Complications and Syndromes
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Pelvic and Acetabular Injuries
- Diabetes and associated disorders
- Technology and Security Systems
- Spine and Intervertebral Disc Pathology
- Nail Diseases and Treatments
- Fungal Infections and Studies
- Animal Genetics and Reproduction
- Pharmacological Effects and Toxicity Studies
- Anesthesia and Pain Management
- Chromatin Remodeling and Cancer
- Head and Neck Surgical Oncology
- Cerebral Venous Sinus Thrombosis
- Myasthenia Gravis and Thymoma
- Atrial Fibrillation Management and Outcomes
- Medical Imaging and Analysis
- Ocular Oncology and Treatments
Memorial Hospital of South Bend
2025
Kokura Memorial Hospital
2021-2024
Kyoto University
2021-2022
Shizuoka Children's Hospital
2018
Otsu Municipal Hospital
2017
Kobe City Medical Center General Hospital
2013-2016
Johnson & Johnson (United States)
2013
Boston Scientific (United States)
2013
FX Palo Alto Laboratory
2013
Foundation for Biomedical Research and Innovation
2013
Chronic subdural hematoma (CSDH) has been recognized as a benign disease, but its clinical outcome is not well documented. This study aims to expand the knowledge base regarding of CSDH. We retrospectively reviewed characteristics CSDH operated in Kobe City Medical Center General Hospital between June 2005 and 2012. Variants included age at onset, sex, laterality, presence headache, consciousness level, risk factors for hemorrhage such malignancy or intake anticoagulants. A total 368 cases...
In patients with ischemic stroke, DWI lesions can occasionally be reversed by reperfusion therapy. This study aimed to ascertain the relationship between ADC levels and reversal in acute stroke who underwent recanalization treatment.We conducted a retrospective cohort endovascular mechanical thrombectomy successful April 2017 March 2021. was assessed through follow-up MR imaging approximately 24 hours after treatment.In total, 118 were included. confirmed 42 patients. The level significantly...
Abstract Perampanel belongs to a novel class of antiseizure medications (ASMs). Studies examining the effect hemodialysis on perampanel serum levels in clinical settings are lacking. We aimed evaluate changes during hemodialysis. studied patients with seizures who received oral between April 2020 and March 2023 whose concentration was measured before after analyzed concentrations levetiracetam lacosamide for comparison. Fourteen patients, mean age 76.1 ± 7.88 years, were included. The dose...
During Onyx embolization to treat brain arteriovenous malformation (AVM), carefully observing the penetration of nidus is important in order avoid complications such as hemorrhage, ischemia, and difficulty with microcatheter removal. We encountered a case extravasation during cerebellar AVM confirmed by surgical resection pathological analysis. The patient was 44-year-old man Spetzler-Martin grade I who underwent prior AVM. While injecting into using “plug-and-push” technique, observed....
三叉神経の機械的刺激により徐脈, 血圧低下や心停止を起こすことがあり, 三叉迷走神経反射と呼ばれる. 今回われわれはテント上未破裂脳動脈瘤クリッピング術中に, 硬膜の刺激による三叉迷走神経反射が原因と思われる心停止をきたした症例を2例経験したので報告する. 代表症例は63歳の女性で, 未破裂動脈瘤に対して開頭クリッピング術を施行した. クリップを脳動脈瘤に近づけた際に, クリップが硬膜に接触したところ4∼5秒間の心停止を2回きたした. 術中操作の中断ですぐに回復し, 手術後の経過は問題なかった. 硬膜刺激による三叉迷走神経反射はすべての開頭手術で起こる可能性があり, テント上未破裂脳動脈瘤クリッピング術でもその頻度は低くない. 生じた場合はすみやかに術中操作を中断することが最も確実な対処法である.
Carotid artery stenting (CAS) has been established as an effective surgical treatment for internal carotid stenosis and/or common (ICAS/CCAS). Typically, CAS is performed via a transfemoral, transbrachial, or transradial approach. However, direct puncture (DP-CAS) preferred in cases where conventional access routes are challenging, such the presence of cervical vascular tortuosity thoracic aortic aneurysm. Since 2020, our institution selectively adopted DP-CAS, utilizing 3D exoscopy through...
Carotid artery stenosis is a significant cause of ischemic stroke, often necessitating interventions like carotid stenting (CAS) to restore adequate blood flow. However, complications intraprocedural arterial dissection can arise during the procedure. This report presents case CAS using CASPER Rx stent. A 77-year-old male, previously diagnosed with asymptomatic right internal (ICA) two years earlier, was presented our institution transient left upper limb paralysis. stent planned due...
要旨 【目的】大腿静脈穿刺による経静脈的塞栓術(transvenous embolization; TVE)が困難な海綿静脈洞部硬膜動静脈瘻(cavernous sinus dural arteriovenous fistula; CSdAVF)に対して,シルビウス静脈を直接穿刺しTVE を行った症例を経験したので報告する.【症例】72 歳,女性.眼球結膜充血の精査でCSdAVF と診断した.主な流出路はシルビウス静脈への逆流であり,右側頭葉に無症候性の脳内出血を認めた.下錐体静脈洞経由など大腿静脈からはアクセスできず,開頭下にシルビウス静脈を留置針で直接穿刺し,術中脳血管撮影を併用してTVE を行い,シャントを閉塞した.【結論】シルビウス静脈への逆流が多く大腿静脈穿刺によるTVE が困難なCSdAVF は,シルビウス静脈の直接穿刺がアプローチルートとして有用であると考えられた.
Fenestration of the cavernous segment internal carotid artery (ICA) is an extremely rare variant with unknown clinical significance. We present two cases this variant, both which were associated a persistent primitive trigeminal (PPTA). Large dual channels ICA seen extending from part immediately distal to origin PPTA C3 ICA. speculate that coexistence vascular anomalies might be due failed regression or remnant arterial network during same early gestation period in development PTA takes...
要旨 【目的】大腿静脈穿刺による経静脈的塞栓術(transvenous embolization; TVE)が困難な海綿静脈洞部硬膜動静脈瘻(cavernous sinus dural arteriovenous fistula; CSdAVF)に対して,シルビウス静脈を直接穿刺しTVE を行った症例を経験したので報告する.【症例】72 歳,女性.眼球結膜充血の精査でCSdAVF と診断した.主な流出路はシルビウス静脈への逆流であり,右側頭葉に無症候性の脳内出血を認めた.下錐体静脈洞経由など大腿静脈からはアクセスできず,開頭下にシルビウス静脈を留置針で直接穿刺し,術中脳血管撮影を併用してTVE を行い,シャントを閉塞した.【結論】シルビウス静脈への逆流が多く大腿静脈穿刺によるTVE が困難なCSdAVF は,シルビウス静脈の直接穿刺がアプローチルートとして有用であると考えられた.
Background and objective It has long been believed that the bony carotid canal no plasticity a small represents hypoplastic internal artery. We aimed to show whether can narrow according morphological changes in Materials methods The diameter was longitudinally measured seven individuals who underwent artery ligation. As moyamoya disease is known be associated with negative remodeling of artery, 106 patients disease, an association outer or correlation stage investigated. by computed...
Introduction: Recently, we reported that apparent diffusion coefficient (ADC) values are independently associated with diffusion-weighted imaging (DWI) reversal, and DWI lesions mean ADC ≥ 520 х 10 -6 mm 2 /s salvageable by mechanical thrombectomy. These areas regain neurological function. This study aimed to determine the effectiveness of thrombectomy in especially large ischemic regions /s. Materials Methods: We conducted a retrospective cohort including patients acute stroke who underwent...
【目的】頚動脈ステント留置(carotid artery stenting;CAS)時にMo. Ma Ultra(以下Mo. Ma)を使用し, ステントデリバリーシステムの回収に難渋した症例を経験したので,その機序と安全に回収するために行うべき手技について報告する.【症例】代表症例1:81歳,男性.症候性頚動脈狭窄にMo. Maを用いてCASを行ったが,ステントデリバリーシステムの回収に難渋した.【結論】Mo. Ma使用時にステントデリバリーシステムが回収困難になる原因は,ステント先端マーカーがMo. Maの出口ポートで引っかかることである.Preciseステントのアウターシースを確実にリシースすることによりシステムを回収することができた.
現在の脳動脈瘤に対する血管内治療は離脱型コイルをできるだけタイトに瘤内に塞栓することにより出血を防ぐことが基本である. いわゆるシンプルテクニックでは十分な結果が期待できない場合は, アドバンスト手技を用いる. ダブル (マルチプル) カテーテル法は, 不規則な形状で, バルーンやステントが使いづらい血管構築やアクセスが困難な場合に選択する. バルーンアシスト法は, ハイパーコンプライアントバルーンによりネックをカバーしながらコイル塞栓する. ステントアシスト法は, 頭蓋内ステントを留置しコイル塞栓する. 血管内治療の適応拡大と長期成績の向上に寄与しているが, 複雑な手技や抗血栓療法に伴う合併症に留意しなければならない.