Tamara Da Silva

ORCID: 0000-0002-4010-0992
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About
Contact & Profiles
Research Areas
  • Long-Term Effects of COVID-19
  • Periodontal Regeneration and Treatments
  • Shoulder Injury and Treatment
  • Knee injuries and reconstruction techniques
  • Dermatological and COVID-19 studies
  • HIV/AIDS drug development and treatment
  • Osteoarthritis Treatment and Mechanisms
  • HIV Research and Treatment
  • Stress and Burnout Research
  • COVID-19 Clinical Research Studies
  • Respiratory Support and Mechanisms
  • HIV/AIDS Research and Interventions

University Hospital of Geneva
2024

Hospital Naval Almirante Nef
2022

University of Valparaíso
2022

SARS-CoV-2 mainly infects respiratory endothelial cells, which is facilitated through its spike protein binding to heparan sulphate. Calcium dobesilate (CaD) a well-established, widely available vasoactive and angioprotective drug interacting with sulphate, the potential interfere uptake of by epithelial cells. The CADOVID trial aims evaluate efficacy safety CaD in reducing viral load non-hospitalised adult patients diagnosed COVID-19, confirmed positive PCR, including reduce impact...

10.1136/bmjopen-2023-079574 article EN cc-by-nc BMJ Open 2024-05-01

<sec> <title>BACKGROUND</title> Available evidence on the conservative treatment of osteoarthritis still leaves place for questioning efficacy Platelet-Rich Plasma (PRP) and whether Stromal Vascular Fraction (SVF) offers a superior therapeutic tool. </sec> <title>OBJECTIVE</title> To assess clinical SVF as adjuvant therapy to PRP functionality tissue regeneration osteoarthritis. <title>METHODS</title> In multi-centric, randomized, triple-blind controlled trial, 130 individuals with will be...

10.2196/preprints.62659 preprint EN cc-by 2024-06-11

Abstract The SIMPL’HIV study investigated whether switching to dolutegravir (DTG) + emtricitabine (FTC) was noninferior continuing combined antiretroviral therapy for maintaining HIV-1 suppression at 144 weeks. demonstrated that viral suppression, CD4 gains, adverse events, quality of life, and patient satisfaction were comparable between groups, confirming DTG FTC’s safety efficacy long-term management infection.

10.1093/ofid/ofae618 article EN cc-by Open Forum Infectious Diseases 2024-10-16

Available evidence on the conservative treatment of knee osteoarthritis still leaves questions about efficacy platelet-rich plasma (PRP) and whether stromal vascular fraction (SVF) offers a superior therapeutic tool. This study aims to assess clinical SVF as adjuvant therapy PRP functionality tissue regeneration for osteoarthritis. In multicenter, randomized, triple-blind, controlled trial, 108 individuals with will be block-randomized in 1:1 ratio. Patients receive an initial single or +...

10.2196/62659 article EN cc-by JMIR Research Protocols 2024-06-11

<b>Introduction:</b> The SARS-CoV 2 pandemic has brought a high burden of disease. Its long-term repercussions are still under investigation. objective this report was to evaluate the occupational, clinical, and functional respiratory recovery at 3 months patients hospitalized for COVID-19, related ventilatory therapy received. Materials methods: Prospective cohort 116 from Hospital Naval Almirante Nef de Viña del Mar, Chile, with clinical follow-up months. <b>Results:</b> Median 100 days....

10.1183/13993003.congress-2022.1485 article EN 10.01 - Respiratory infections and bronchiectasis 2022-09-04
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