A5054183434- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Respiratory Support and Mechanisms
- Dermatological and COVID-19 studies
- Chronic Lymphocytic Leukemia Research
- Systemic Lupus Erythematosus Research
- Sepsis Diagnosis and Treatment
- Erythrocyte Function and Pathophysiology
- COVID-19 Impact on Reproduction
- Hematological disorders and diagnostics
- Erythropoietin and Anemia Treatment
- Thermal Regulation in Medicine
- Cancer Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Eosinophilic Disorders and Syndromes
- Sarcoma Diagnosis and Treatment
- Iron Metabolism and Disorders
- Inflammasome and immune disorders
- Urticaria and Related Conditions
- Diabetes and associated disorders
- SARS-CoV-2 and COVID-19 Research
- Systemic Sclerosis and Related Diseases
- Complement system in diseases
Assistance Publique Hôpitaux de Marseille
2020-2025
Hôpital de la Conception
2020-2022
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2022
Aix-Marseille Université
2020-2022
Unité de recherche sur les maladies cardiovasculaires et métaboliques
2022
Inserm
2021-2022
Around the tenth day after diagnosis, ∼20% of patients with coronavirus disease 2019 (COVID-19)−associated pneumonia evolve toward severe oxygen dependence (stage 2b) and acute respiratory distress syndrome 3) associated systemic inflammation often termed a “cytokine storm.” Because interleukin-1 (IL-1) blocks production IL-6 other proinflammatory cytokines, we treated COVID-19 early in IL-1 receptor antagonist, anakinra. We retrospectively compared 22 from three different centers France...
Abstract Beside the commonly described pulmonary expression of coronavirus disease 2019 (COVID-19), major vascular events have been reported. The objective this study was to investigate whether increased levels circulating endothelial cells (CECs) might be associated with severe forms COVID-19. Ninety-nine patients COVID-19 were enrolled in retrospective study. Patients intensive care units (ICU) had significantly higher CEC counts than non-ICU and extent injury correlated putative markers...
ABSTRACT Introduction The causes of cytopenias are numerous, and the bone marrow aspirate helps to identify them. In rare cases, these due metastases from solid cancers. techniques used in hematology laboratories limited characterizing cells. Interaction with cytopathology laboratory becomes critical for tumor cells completing a comprehensive diagnosis aspirate. Methods This article describes series 38 aspirates 36 patients bicytopenias who underwent aspiration whom hematologists sent sample...
During SARS-CoV-2 infection, eosinopenia may reflect a hyperactive immune response. In this study of hospitalized COVID-19 patients, we aimed to better understand the prognostic value severe (absolute eosinophil count = 0 G/L) and decipher its underlying mechanisms. We retrospectively analyzed records patients from March June 2020 in three university hospitals Marseille, France. assessed association between composite poor outcome these including need for oxygen supplementation at >6 L/min,...
Background Tocilizumab and anakinra are anti-interleukin drugs to treat severe coronavirus disease 2019 (COVID-19) refractory corticosteroids. However, no studies compared the efficacy of tocilizumab versus guide choice therapy in clinical practice. We aimed compare outcomes COVID-19 patients treated with or anakinra. Methods Our retrospective study was conducted three French university hospitals between February 2021 2022 included all consecutive hospitalized a laboratory-confirmed acute...
Dexamethasone has demonstrated efficacy in reducing mortality COVID-19. However, its practical use is badly defined. We aimed to investigate factors associated with dexamethasone real life. Our retrospective study was conducted two university hospitals between September and November 2020 included all the consecutive hospitalized patients a laboratory-confirmed SARS-CoV-2 infection assessed by RT-PCR, treated intravenous (6 mg/day). Among 111 patients, 10.6% necessitated transfer into...