A5064839004- Management of metastatic bone disease
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Systemic Lupus Erythematosus Research
- Neurofibromatosis and Schwannoma Cases
- Cytomegalovirus and herpesvirus research
- Meningioma and schwannoma management
- T-cell and B-cell Immunology
- Diabetes and associated disorders
- Celiac Disease Research and Management
- Parvovirus B19 Infection Studies
- Liver Diseases and Immunity
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cancer Treatment and Pharmacology
- Glioma Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Cancer Diagnosis and Treatment
- Spinal Hematomas and Complications
- Pain Management and Opioid Use
- Bone Tumor Diagnosis and Treatments
- Toxoplasma gondii Research Studies
- Autoimmune Bullous Skin Diseases
- Lung Cancer Treatments and Mutations
- Galectins and Cancer Biology
- Sarcoma Diagnosis and Treatment
Memorial Sloan Kettering Cancer Center
2017-2025
AO Foundation
2023
AOSpine
2023
Neurological Surgery
2017-2022
Cornell University
2017-2022
Oxford University Press (United Kingdom)
2020
Neurology, Inc
2017-2019
Tel Aviv Sourasky Medical Center
2012-2018
Tel Aviv University
2007-2018
Vancouver Coastal Health
2017
OBJECTIVE An analysis of factors contributing to durable radiographic control spinal metastases was undertaken, drawing from a large single-institution database in an attempt elucidate indications and dose requirements for successful treatment. METHODS All patients treated at single institution with stereotactic radiosurgery (SRS) the spine as first-line therapy were assessed local progression site, defined enlargement tumor and/or biopsy-proven evidence active cells. followed CT, PET, or MR...
To date, it is believed that the origin of autoimmune diseases one a multifactorial background. A genetic predisposition, an immune system malfunction or even backfire, hormonal regulation, and environmental factors all play important roles in pathogenesis diseases. Among these factors, role infection known to be major one. Epstein-Barr virus (EBV) cytomegalovirus (CMV) are considered notorious as they consistently associated with multiple cohort 1595 serum samples, 23 different disease...
Awake craniotomy for removal of intraaxial tumors within or adjacent to eloquent brain regions is a well-established procedure. However, awake failures have not been well characterized. In the present study, authors aimed analyze and assess incidence causes failed craniotomy.The database craniotomies performed at Tel Aviv Medical Center between 2003 2010 was reviewed. considered failure if conversion general anesthesia required, adequate mapping monitoring could achieved.Of 488 patients...
Awake craniotomy (AC) for removal of intra-axial brain tumors is a well-established procedure. However, the occurrence and consequences intraoperative seizures during AC have not been well characterized.To analyze incidence, risk factors, AC.The database at Tel Aviv Medical Center between 2003 to 2011 was reviewed. Occurrences were analyzed with respect medical history, medications, tumor characteristics, postoperative outcome.Of 549 ACs performed index period, 477 complete records...
Study Design: Literature review. Objective: To provide an overview of the recent advances in spinal oncology, emphasizing key role surgeon treatment patients with metastatic tumors. Methods: Results: Therapeutic led to longer survival times among cancer patients, placing significant emphasis on durable local control, optimization quality life, and daily function for Recent integration modern diagnostic tools, precision oncologic treatment, widespread use new technologies has transformed...
Infections can act as environmental triggers that induce or promote systemic lupus erythematosus (SLE) in genetically predisposed individuals. New technologies, developed recently, enable simultaneous assessment of multiple antibodies. Antibodies to specific infectious agents may shed light into the mechanisms induction SLE. The aim this study was investigate prevalence seropositivity and titers antibodies bacterial, viral, parasitic SLE patients compared with non-autoimmune controls. Sera...
Abstract BACKGROUND Despite major advances in radiation and systemic treatments, surgery remains a critical step the multidisciplinary treatment of metastatic spinal cord tumors. OBJECTIVE To describe indications, rationale, technique “hybrid therapy” (separation concomitant spine stereotactic radiosurgery [SRS]) along with practical nuances. METHODS Separation describes posterolateral approach for circumferential epidural decompression stabilization. The goal is to decompress cord,...
Over the last 2 decades, advances in systemic therapy have increased expected overall survival for patients with cancer. It is unclear whether same benefit has been conferred to requiring surgery metastatic spinal disease.To examine trends postoperative over a 20-yr period surgically treated disease.Data were obtained 1515 who underwent epidural cord compression or tumor-related mechanical instability. Postoperative was calculated all included using Kaplan-Meier methodology from date of...
A bstract : The BioPlex™ 2200 ANA Screen is a fully automated system that determines levels for 13 different autoimmune antibodies of established clinical significance. objective this study was to determine the specificity assay and analyze antibody profile samples collected from healthy subjects against comparative ELISA IIF screening methods. total 510 specimens were randomly selected cohort apparently blood bank donors. Samples distributed five age brackets. All tested using Bio‐Rad's...
Infections may act as environmental triggers for the induction of systemic lupus erythematosus (SLE). In this study, we determine relationship between disease manifestations SLE patients and titers five Epstein–Barr virus (EBV) Abs. We evaluated early antigen IgG (EAG), nuclear IgG, viral capsid (VCA) IgM, heterophile using BioPlex 2200 multiplexed immunoassay method in 260 sera (120 140 controls). EAG were significantly elevated ( P < 0.024) with cutaneous symptoms increased anti‐Ro...
Type 1 diabetes mellitus (T1DM) is an autoimmune disease with complex interactions between genetic and environmental factors. We compared antibody levels to various infectious agents of autoimmune-associated autoantibodies Colombian T1DM patients, their close family members healthy controls. Significantly lower antibodies against several were detected in the patients. These included Helicobacter pylori (P = 0.01), cytomegalovirus 0.001), Epstein-Barr virus 0.02) Toxoplasma 0.001). patients...
The aim of this study was to reevaluate the role infection in inflammatory bowel disease (IBD). Sera from 119 patients with IBD [80 Crohn's (CD); 39 ulcerative colitis] and 98 healthy controls were assessed using Bio-Rad BioPlex 2200 for presence Toxoplasma gondii, cytomegalovirus, Epstein-Barr virus, Treponema pallidum, Saccharomyces cerevisiae. Hepatitis B hepatitis C virus (HCV), anti-Helicobacter pylori antibodies by ELISA. In addition, sera tested a panel associated thrombophilia as...